Protein Alignment rst and LOC1272050

DIOPT Version :10

• Sequence 1: NP_525058.2
• Gene: rst / 31290
• FlyBaseID: FBgn0003285
• Length: 764
• Species: Drosophila melanogaster
• Sequence 2: XP_061506935.1
• Gene: LOC1272050 / 1272050
• VectorBaseID: AGAMI1_009952
• Length: 941
• Species: Anopheles gambiae
• Alignment Length: 855
• Identity: 403/855 - (47%)
• Similarity: 509/855 - (59%)
• Gaps: 160/855 - (18%)

  Fly     7 LLLLATIVGMVRSSPYT---SYQ-NQRFAMEPQDQTAVVGARVTLPCRVINKQGTLQWTKDDFGL 67
            |.||..:.|..:.||..   |.| .||||||||||||:||:||||||||:||.|.||||||||||
Mosquito    30 LFLLLRVGGGAKVSPAAGSGSRQLEQRFAMEPQDQTAIVGSRVTLPCRVVNKSGQLQWTKDDFGL 94

  Fly    68 GTSRDLSGFERYAMVGSDEEGDYSLDIYPVMLDDDARYQCQVSPGPEGQPAIRSTFAGLTVLVPP 132
            ||.|:|||||||.|||||||||:||||.||||||||:|||||.||..|.|.|||.||.|||||||
Mosquito    95 GTHRNLSGFERYTMVGSDEEGDFSLDISPVMLDDDAKYQCQVGPGRGGTPGIRSRFAKLTVLVPP 159

  Fly   133 EAPKITQGDVIYATEDRKVEIECVSVGGKPAAEITWIDGLGNVLTDNIEYTVIPLPDQRRFTAKS 197
            |||||.|||.:..||||::|:||||||||||||||||||||.|||..|||...||.|.||:||||
Mosquito   160 EAPKIVQGDFMVTTEDREIELECVSVGGKPAAEITWIDGLGTVLTRGIEYMKEPLRDARRYTAKS 224

  Fly   198 VLRLTPKKEHHNTNFSCQAQNTADRTYRSAKIRVEVKYAPKVKVNVMGSLPGGAGGSVGGAGGGS 262
            :|:||||||||||.|:|||||||||||||.::::|||||||||:.|:|          |...||
Mosquito   225 ILKLTPKKEHHNTTFTCQAQNTADRTYRSVRLKLEVKYAPKVKIAVIG----------GALNGG- 278

  Fly   263 VHMSTGSRIVEHSQVRLECRADANPSDVRYRWFINDEPIIGGQKTEMVIRNVTRKFHDAIVKCEV 327
                   ||:|.::|||.|||||||.||.||||:.:|...|...:|::|.|::||:|...|:|||
Mosquito   279 -------RILEGTEVRLSCRADANPPDVTYRWFVGEELSDGSHASELLIANISRKYHGTTVRCEV 336

  Fly   328 QNSVGKSEDSETLDISYAPSFRQRPQSMEADVGSVVSLTCEVDSNPQPEIVWIQHPSDRVVGTST 392
            :|:|||||:|.||||||.||||..|||:|||..:.|:|.|:||.||.|:::||..|||:||.::.
Mosquito   337 RNAVGKSEESVTLDISYGPSFRAPPQSVEADPDTTVTLGCDVDGNPAPDVLWIHEPSDQVVSSAA 401

  Fly   393 NLTFSVSNETAGRYYCKANVPGYAEISADAYVYLKGSPAIGSQRTQYGLVGDTARIECFASSVPR 457
            |:|..|:..|||||||||:|.|:||:.|||.|||:|.|||.|.|.|||.|.|:|::||.|.|:|:
Mosquito   402 NVTLVVTPATAGRYYCKASVQGFAEVEADATVYLRGPPAISSPRQQYGAVHDSAQLECVALSIPK 466

  Fly   458 ARHVSWTFNGQEI--SSE-SGHDYSILVDAVPGGVKSTLIIRDSQAYHYGKYNCTVVNDYGNDVA 519
            .|||.|:|||:||  |:| :..:|..|...:|.||:|||||...|..|:|:||||||||||.|..
Mosquito   467 PRHVLWSFNGREINVSAEPNAAEYRALDSPIPNGVRSTLIIHHCQREHFGRYNCTVVNDYGIDYL 531

  Fly   520 EIQLQAKKSVSLLMTIVGGISVVAFLLVLTILVVVYIKCKKRTK-LPPADVI------------- 570
            ||:..:|:...|.:.::|.:..:..|::|.::.:.....:.|.| |||||||
Mosquito   532 EIEFVSKEPNLLPVIVLGSLGGITILIILVVIAICLCSRRNRKKHLPPADVIPKYDVPGKDCGEH 596

  Fly   571 -----SEHQI--------------------------------TKNGGVSCKLE--PGDRTSNYSD 596
                 |:|:|                                |....:|..|.  .||.|::||.
Mosquito   597 GGTTVSDHKIDRIDDMLDGEHPRDTITTNIALNVRSGVAGPQTGTTAISSSLTALKGDTTTDYSR 661

  Fly   597 LKVDI----------------------------------SGGYVPYGDYSTHYSPPPQYLTTCST 627
            ...|.                                  |.|||||.:|:..||||.|:|  ...
Mosquito   662 YSGDFSDSLSHLQCPKVGGGPTGTSGNSTSSTGNSTSNNSNGYVPYVNYARDYSPPTQHL--MQF 724

  Fly   628 KSNGSSTIMQNNHQNQLQLQ-QQQQQSHHQHHTQTTTL-----PMTFLTNSSGGSLTGSIIGSRE 686
            |::.||    |:..|.|..: ..:..::.|..|.|.||     |..  ...:||:
Mosquito   725 KASSSS----NSIGNALTAKPPARPPANGQLPTGTMTLTRKRTPAA--PPDAGGA---------- 773

  Fly   687 IRQDNGLPSLQSTTASVVSSSPNGSCSNQSTTAATTTTTHVVVPSSMALSVDPRYSAIYGNPYLR 751
                  |||:||:    |||.|||            ...|.::  ...|.:|.|:.|.||..:.|
Mosquito   774 ------LPSIQSS----VSSIPNG------------LMNHPML--GCHLGLDTRFGANYGTLHGR 814

  Fly   752 SSNSSLLPPP 761
            ..:...||||
Mosquito   815 GPSPMQLPPP 824

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rst	NP_525058.2	Ig	29..110	CDD:472250	69/80 (86%)
		Ig strand B	45..49	CDD:409353	3/3 (100%)
		Ig strand E	90..94	CDD:409353	2/3 (67%)
		Ig strand F	104..109	CDD:409353	3/4 (75%)
		C2-set_2	135..225	CDD:400489	68/89 (76%)
		Ig strand B	151..155	CDD:409353	1/3 (33%)
		Ig strand C	165..169	CDD:409353	3/3 (100%)
		Ig strand E	197..201	CDD:409353	2/3 (67%)
		Ig strand F	211..216	CDD:409353	2/4 (50%)
		Ig strand G	226..229	CDD:409353	1/2 (50%)
		Ig	271..340	CDD:472250	37/68 (54%)
		Ig_3	346..411	CDD:464046	36/64 (56%)
		Ig	428..524	CDD:472250	54/98 (55%)
		Ig strand B	446..450	CDD:409353	1/3 (33%)
		Ig strand C	460..464	CDD:409353	2/3 (67%)
		Ig strand E	491..495	CDD:409353	3/3 (100%)
		Ig strand F	505..510	CDD:409353	3/4 (75%)
		Ig strand G	518..521	CDD:409353	0/2 (0%)
LOC1272050	XP_061506935.1	None