DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3603 and NRE1

DIOPT Version :9

Sequence 1:	NP_001259199.1	Gene:	CG3603 / 31289	FlyBaseID:	FBgn0029648	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	NP_012301.3	Gene:	NRE1 / 854853	SGDID:	S000001474	Length:	254	Species:	Saccharomyces cerevisiae

Alignment Length:	205	Identity:	48/205 - (23%)
Similarity:	90/205 - (43%)	Gaps:	22/205 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 GKVALVTGAGSGIGRATCRLL-ARDGAKVIAVDRNLKAAQETVQELGSERSAALEVDVSSAQSVQ 71
            |||.||||...|||::...:| :.|...|:......:|..:.::|...:|...:..|::....::
Yeast     2 GKVILVTGVSRGIGKSIVDVLFSLDKDTVVYGVARSEAPLKKLKEKYGDRFFYVVGDITEDSVLK 66

  Fly    72 FSVAEALKKFQQAPTIVVNSAGITRDGYLLKMPERDYDDV--------YGVNLKGTFLVTQAYAK 128
            ..|..|:|...:..::|.| ||:..       |.::.:::        |.:|.   |.:......
Yeast    67 QLVNAAVKGHGKIDSLVAN-AGVLE-------PVQNVNEIDVNAWKKLYDINF---FSIVSLVGI 120

  Fly   129 AMIEQKLENGTIVNLSSIVAKMNNVGQANYAATKAGVISFTEVASKEFGKFGIRVNCILPGYIDT 193
            |:.|.|..||.:|.:||....|.......|.::||.:..|....:.|  :..::...:.||.:||
Yeast   121 ALPELKKTNGNVVFVSSDACNMYFSSWGAYGSSKAALNHFAMTLANE--ERQVKAIAVAPGIVDT 183

  Fly   194 PMVAVVPDSV 203
            .|...:.::|
Yeast   184 DMQVNIRENV 193

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3603	NP_001259199.1	fabG	6..248	CDD:235546	48/205 (23%)
CG3603	NP_001259199.1	BKR_SDR_c	9..248	CDD:187594	47/204 (23%)
NRE1	NP_012301.3	SPR-like_SDR_c	4..246	CDD:187625	46/203 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000019
OrthoInspector	1	1.000	-	-		otm46682
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1710
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.940