Protein Alignment CG3603 and Hsd17b14

DIOPT Version :10

• Sequence 1: NP_570046.1
• Gene: CG3603 / 31289
• FlyBaseID: FBgn0029648
• Length: 249
• Species: Drosophila melanogaster
• Sequence 2: NP_001178040.1
• Gene: Hsd17b14 / 691018
• RGDID: 1588673
• Length: 270
• Species: Rattus norvegicus
• Alignment Length: 256
• Identity: 76/256 - (29%)
• Similarity: 128/256 - (50%)
• Gaps: 20/256 - (7%)

  Fly     2 SVGVLAGKVALVTGAGSGIGRATCRLLARDGAKVIAVDRNLKAAQETVQELGSERSAALEVDVSS 66
            :||..:|||.:|||...|||.|..|.....||:|:..|::....:...|||..  :..:..||:.
  Rat     3 AVGRYSGKVVVVTGGSRGIGAAIVRAFVDSGAQVVFCDKDEAGGRAVEQELLG--TVFIPGDVTQ 65

  Fly    67 AQSVQFSVAEALKKFQQAPTIVVNSAGITRDGYLLKMPE----RDYDDVYGVNLKGTFLVTQAYA 127
            ...:|..::|.:.:|... ..|||:||.....   ::||    :.:..:...||.|.:.:.:.
  Rat    66 EGDLQTLISETVSRFGHL-DCVVNNAGYHPPA---QLPEETSAQGFRQLLEENLLGAYTLIKL-- 124

  Fly   128 KAMIEQKLENGTIVNLSSIVAKMNNVGQANYAATKAGVISFTEVASKEFGKFGIRVNCILPGYID 192
             |:...:...|.|:|:||:|..:.......|.|||..|.:.|:..:.:..::|:|||||.||.|.
  Rat   125 -ALPHLRKSKGNIINISSLVGAIGQSQALTYVATKGAVTAMTKALALDESRYGVRVNCISPGNIW 188

  Fly   193 TPM---VAVVPDSVKQEVVQRC---PLGRLGQPEEIAEVIAFLASPQSSYVNGAAIEVTGG 247
            ||:   :|......:..:::..   ||||:|||.|:.....|||| ::::..|..:.:|||
  Rat   189 TPLWQELAAATSDPRATILEGTLAQPLGRMGQPAEVGAAAVFLAS-EATFCTGLELFMTGG 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3603	NP_570046.1	BKR_SDR_c	9..248	CDD:187594	73/249 (29%)
Hsd17b14	NP_001178040.1	Rossmann-fold NAD(P)(+)-binding proteins	1..256	CDD:473865	76/256 (30%)