DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3603 and hsd17b8

DIOPT Version :9

Sequence 1:	NP_001259199.1	Gene:	CG3603 / 31289	FlyBaseID:	FBgn0029648	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	NP_001016671.1	Gene:	hsd17b8 / 549425	XenbaseID:	XB-GENE-490296	Length:	255	Species:	Xenopus tropicalis

Alignment Length:	247	Identity:	121/247 - (48%)
Similarity:	162/247 - (65%)	Gaps:	4/247 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LAGKVALVTGAGSGIGRATCRLLARDGAKVIAVDRNLKAAQETVQ----ELGSERSAALEVDVSS 66
            |...:|||||.|||||||.|:.|:.:||.|:.||.::.:|..|:|    .|..:..||...|||.
Frog     7 LKSMLALVTGGGSGIGRAICQRLSVEGASVVVVDLDISSANATLQTLSHNLSGQEHAAFATDVSK 71

  Fly    67 AQSVQFSVAEALKKFQQAPTIVVNSAGITRDGYLLKMPERDYDDVYGVNLKGTFLVTQAYAKAMI 131
            |..|...:.:...::...|.|.::|||||:|.:||::.|..:|.|..|||||.||:|||.|:|::
Frog    72 ANHVNSLMQKIQGRYSVPPRIAISSAGITKDEFLLRLSEESFDSVLNVNLKGPFLITQAVARAIV 136

  Fly   132 EQKLENGTIVNLSSIVAKMNNVGQANYAATKAGVISFTEVASKEFGKFGIRVNCILPGYIDTPMV 196
            ......|:|:|:.|||.|:.|:||:||||:||||...|:.|:||..|||||.|.:|||:|.|||.
Frog   137 ASGEHGGSIINIGSIVGKVGNLGQSNYAASKAGVEGLTKTAAKELAKFGIRCNTVLPGFISTPMT 201

  Fly   197 AVVPDSVKQEVVQRCPLGRLGQPEEIAEVIAFLASPQSSYVNGAAIEVTGGL 248
            ..||..|..:.....||||||.||:||:|.|||||..|.|:.||:|||||||
Frog   202 DKVPQKVLDKFAGMVPLGRLGYPEDIADVCAFLASDDSKYITGASIEVTGGL 253

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3603	NP_001259199.1	fabG	6..248	CDD:235546	119/245 (49%)
CG3603	NP_001259199.1	BKR_SDR_c	9..248	CDD:187594	118/242 (49%)
hsd17b8	NP_001016671.1	BKR_SDR_c	11..254	CDD:187594	120/243 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	213	1.000	Domainoid score	I2704
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H56588
Inparanoid	1	1.050	217	1.000	Inparanoid score	I3499
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1226147at2759
OrthoFinder	1	1.000	-	-		FOG0000019
OrthoInspector	1	1.000	-	-		oto103064
Panther	1	1.100	-	-	LDO	PTHR42760
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1710
SonicParanoid	1	1.000	-	-		X181
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.190