Protein Alignment CG3603 and HSD17B14

DIOPT Version :9

• Sequence 1: NP_001259199.1
• Gene: CG3603 / 31289
• FlyBaseID: FBgn0029648
• Length: 249
• Species: Drosophila melanogaster
• Sequence 2: NP_057330.2
• Gene: HSD17B14 / 51171
• HGNCID: 23238
• Length: 270
• Species: Homo sapiens
• Alignment Length: 259
• Identity: 82/259 - (31%)
• Similarity: 137/259 - (52%)
• Gaps: 23/259 - (8%)

  Fly     1 MSVGV-LAGKVALVTGAGSGIGRATCRLLARDGAKVIAVDRNLKAAQETVQELGSERSAALEVDV 64
            |:.|. .||||.:|||.|.|||....|.....||:|:..|::....:...|||..  :..:..||
Human     1 MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPG--AVFILCDV 63

  Fly    65 SSAQSVQFSVAEALKKFQQAPTIVVNSAGITRDGYLLKMPE----RDYDDVYGVNLKGTFLVTQA 125
            :....|:..|:|.:::|.:. ..|||:||.....   :.||    :.:..:..:||.||:.:|:.
Human    64 TQEDDVKTLVSETIRRFGRL-DCVVNNAGHHPPP---QRPEETSAQGFRQLLELNLLGTYTLTKL 124

  Fly   126 YAKAMIEQKLENGTIVNLSSIVAKMNNVGQANYAATKAGVISFTEVASKEFGKFGIRVNCILPGY 190
               |:...:...|.::|:||:|..:.......|.|||..|.:.|:..:.:...:|:|||||.||.
Human   125 ---ALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGN 186

  Fly   191 IDTP----MVAVVPD---SVKQEVVQRCPLGRLGQPEEIAEVIAFLASPQSSYVNGAAIEVTGG 247
            |.||    :.|::||   ::::.::.: ||||:|||.|:.....|||| ::::..|..:.||||
Human   187 IWTPLWEELAALMPDPRATIREGMLAQ-PLGRMGQPAEVGAAAVFLAS-EANFCTGIELLVTGG 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3603	NP_001259199.1	fabG	6..248	CDD:235546	80/253 (32%)
		BKR_SDR_c	9..248	CDD:187594	78/250 (31%)
HSD17B14	NP_057330.2	RDH_SDR_c	1..256	CDD:187638	82/259 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000019
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1710
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.940