DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3603 and cbr4

DIOPT Version :9

Sequence 1:	NP_001259199.1	Gene:	CG3603 / 31289	FlyBaseID:	FBgn0029648	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	NP_001007873.1	Gene:	cbr4 / 493259	XenbaseID:	XB-GENE-5935857	Length:	236	Species:	Xenopus tropicalis

Alignment Length:	242	Identity:	93/242 - (38%)
Similarity:	133/242 - (54%)	Gaps:	12/242 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 KVALVTGAGSGIGRATCRLLARDGAKVIAVDRNLKAAQETVQELGSERSAALEVDVSSAQSVQFS 73
            ||..|.|...|||:|..:|||:...||..:.|:|:.|:....|:|:.  .||..|||....:|.:
Frog     3 KVCAVFGGSRGIGKAVSKLLAQRDYKVAVISRDLEVAKAAAAEVGAH--LALSCDVSKENEIQDT 65

  Fly    74 VAEALKKFQQAPTIVVNSAGITRDGYLLKMPERDYDDVYGVNLKGTFLVTQAYAKAMIEQKLENG 138
            ..|........ ..:||||||.||..||:....|...:..|||.||....:...::||:|  :.|
Frog    66 FKEITNNLGNV-DYLVNSAGIRRDALLLRTRSEDIRSLLSVNLVGTIQTCKLALRSMIQQ--QGG 127

  Fly   139 TIVNLSSIVAKMNNVGQANYAATKAGVISFTEVASKEFGKFGIRVNCILPGYIDTPM-VAVVPDS 202
            .|||:.|||....|:||:.|.|:|.|:|.|::..:||..|..||||.:.||:|.|.| :.:..||
Frog   128 AIVNIGSIVGHKGNIGQSIYGASKEGLIGFSKSLAKEVAKRNIRVNVVAPGFIHTDMTLGLEEDS 192

  Fly   203 VKQEVVQRCPLGRLGQPEEIAEVIAFLASPQSSYVNGAAIEVTGGLK 249
            :.:.|    ||||.|.|||:|:.:.||.  :|.|:.|..:.|.|||:
Frog   193 LTKMV----PLGRFGDPEEVAQSVLFLL--ESPYITGHVLVVDGGLQ 233

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3603	NP_001259199.1	fabG	6..248	CDD:235546	91/239 (38%)
CG3603	NP_001259199.1	BKR_SDR_c	9..248	CDD:187594	91/239 (38%)
cbr4	NP_001007873.1	NADB_Rossmann	3..232	CDD:389744	91/239 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1226147at2759
OrthoFinder	1	1.000	-	-		FOG0000019
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1710
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.950