DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3603 and Cbr4

DIOPT Version :9

Sequence 1:	NP_001259199.1	Gene:	CG3603 / 31289	FlyBaseID:	FBgn0029648	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	NP_872613.1	Gene:	Cbr4 / 359725	RGDID:	727826	Length:	236	Species:	Rattus norvegicus

Alignment Length:	247	Identity:	93/247 - (37%)
Similarity:	131/247 - (53%)	Gaps:	22/247 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 KVALVTGAGSGIGRATCRLLARDGAKVIAVDRNLKAAQETVQELGSERSA-----ALEVDVSSAQ 68
            ||..|.|...|||:|..:|:|:.|.::..|.|||:.|:.|..|||....|     |.|.||
  Rat     3 KVCAVFGGSRGIGKAVAQLMAQKGYRLAIVARNLEVAKATASELGGIHLAFRCNIAKEGDV---- 63

  Fly    69 SVQFSVAEALKKFQQAPTIVVNSAGITRDGYLLKMPERDYDDVYGVNLKGTFLVTQAYAKAMIEQ 133
               .|..|.::|.......:||:|||.||..|::....|.......||.||.|..:|..:.||:|
  Rat    64 ---HSTFEEMEKHLGPVNFLVNAAGINRDSLLVRTKTEDMLSQLHTNLLGTMLTCRAAMRTMIQQ 125

  Fly   134 KLENGTIVNLSSIVAKMNNVGQANYAATKAGVISFTEVASKEFGKFGIRVNCILPGYIDTPMVAV 198
               .|:|||:.||:....|||||.|:|||.|:|.|:...:||..:..||||.:.||:|.|.|.
  Rat   126 ---GGSIVNVGSIIGLKGNVGQAAYSATKGGLIGFSRSLAKEVARKKIRVNVVAPGFIHTDMT-- 185

  Fly   199 VPDSVKQEVVQR-CPLGRLGQPEEIAEVIAFLASPQSSYVNGAAIEVTGGLK 249
              ..:|:|..:: .||||.|:..|:|..:.||.  :|.|:.|..:.|.|||:
  Rat   186 --KHLKEEHFKKNIPLGRFGEALEVAHAVVFLL--ESPYITGHVLIVDGGLQ 233

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3603	NP_001259199.1	fabG	6..248	CDD:235546	91/244 (37%)
CG3603	NP_001259199.1	BKR_SDR_c	9..248	CDD:187594	91/244 (37%)
Cbr4	NP_872613.1	NADB_Rossmann	3..232	CDD:419666	91/244 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1226147at2759
OrthoFinder	1	1.000	-	-		FOG0000019
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100272
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.720