DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3603 and Mfe2

DIOPT Version :9

Sequence 1:	NP_001259199.1	Gene:	CG3603 / 31289	FlyBaseID:	FBgn0029648	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	NP_001285318.1	Gene:	Mfe2 / 32582	FlyBaseID:	FBgn0030731	Length:	598	Species:	Drosophila melanogaster

Alignment Length:	252	Identity:	84/252 - (33%)
Similarity:	123/252 - (48%)	Gaps:	30/252 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 GKVALVTGAGSGIGRATCRLLARDGAKVIAVD---------RNLKAAQETVQEL---GSERSAAL 60
            |:||:|||||:|:||....|.|..||||:..|         .:.:||...|.|:   |.|..|..
  Fly    12 GRVAVVTGAGAGLGREYALLFAERGAKVVVNDLGGTHSGDGASQRAADIVVDEIRKAGGEAVADY 76

  Fly    61 EVDVSSAQSVQFSVAEALKKFQQAPTIVVNSAGITRDGYLLKMPERDYDDVYGVNLKGTFLVTQA 125
            ...:..|:.::    .|:|.|.:. .|:||:|||.||..|:|..|:|::.|..|:|||:|..|||
  Fly    77 NSVIDGAKVIE----TAIKAFGRV-DILVNNAGILRDRSLVKTSEQDWNLVNDVHLKGSFKCTQA 136

  Fly   126 YAKAMIEQKLENGTIVNLSSIVAKMNNVGQANYAATKAGVISFTEVASKEFGKFGIRVNCILPGY 190
            ....|  :|...|.|:..||......|.||.||.|.|.|:|......:.|..:..:..|.|:|..
  Fly   137 AFPYM--KKQNYGRIIMTSSNSGIYGNFGQVNYTAAKMGLIGLANTVAIEGARNNVLCNVIVPTA 199

  Fly   191 IDTPMVAVVPDSVKQEVVQRCPLGRLGQPEEIAEVIAFLASPQSSYVNGAAIEVTGG 247
            .......::||.:..|:          :|:.||.|:|:|.. :|...||:.||...|
  Fly   200 ASRMTEGILPDILFNEL----------KPKLIAPVVAYLCH-ESCEDNGSYIESAAG 245

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3603	NP_001259199.1	fabG	6..248	CDD:235546	84/252 (33%)
CG3603	NP_001259199.1	BKR_SDR_c	9..248	CDD:187594	83/251 (33%)
Mfe2	NP_001285318.1	hydroxyacyl-CoA-like_DH_SDR_c-like	8..257	CDD:187611	84/252 (33%)
		PRK07791	11..248	CDD:236099	84/252 (33%)
		PLN02864	315..598	CDD:178455
		hot_dog	<383..442	CDD:294345
		HDE_HSD	471..592	CDD:239532
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447676
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840