Protein Alignment CG3603 and DHRS4L2

DIOPT Version :9

• Sequence 1: NP_001259199.1
• Gene: CG3603 / 31289
• FlyBaseID: FBgn0029648
• Length: 249
• Species: Drosophila melanogaster
• Sequence 2: NP_932349.2
• Gene: DHRS4L2 / 317749
• HGNCID: 19731
• Length: 232
• Species: Homo sapiens
• Alignment Length: 195
• Identity: 60/195 - (30%)
• Similarity: 93/195 - (47%)
• Gaps: 9/195 - (4%)

  Fly     6 LAGKVALVTGAGSGIGRATCRLLARDGAKVIAVDR---NLKAAQETVQELGSERSAALEVDVSSA 67
            |..||||||.:..|||.|..|.||:|.|.|:...|   |:..|..|:|..|...:..: ..|..|
Human    30 LTNKVALVTASTDGIGFAIARRLAQDRAHVVVSSRKQQNVDQAVATLQGEGLSVTGTV-CHVGKA 93

  Fly    68 QSVQFSVAEALKKFQQAPTIVVNSAGITRDGYLLKMPERDYDDVYGVNLKGTFLVTQAYAKAMIE 132
            :..:..||.|:|.......:|.|:|.....|.|:.:.|..:|....:|:|...|:|:|....|
Human    94 EDRERLVAMAVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKTLDINVKAPALMTKAVVPEM-- 156

  Fly   133 QKLENGTIVNLSSIVAKMNNVGQANYAATKAGVISFTEVASKEFGKFGIRVNCILPGYIDTPMVA 197
            :|...|::|.:|||.|...:.|.:.|..:|..::......:.|.....|||||:   ::|...:|
Human   157 EKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLNNTLAIELAPRNIRVNCL---HLDLSRLA 218

  Fly   198  197
            Human   219  218

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3603	NP_001259199.1	fabG	6..248	CDD:235546	60/195 (31%)
		BKR_SDR_c	9..248	CDD:187594	59/192 (31%)
DHRS4L2	NP_932349.2	NADB_Rossmann	24..>210	CDD:304358	57/182 (31%)
		adh_short	33..210	CDD:278532	56/179 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000019
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X181
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.910