DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3603 and Dhrs4

DIOPT Version :9

Sequence 1:	NP_001259199.1	Gene:	CG3603 / 31289	FlyBaseID:	FBgn0029648	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	NP_695227.2	Gene:	Dhrs4 / 266686	RGDID:	708482	Length:	279	Species:	Rattus norvegicus

Alignment Length:	246	Identity:	77/246 - (31%)
Similarity:	124/246 - (50%)	Gaps:	6/246 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LAGKVALVTGAGSGIGRATCRLLARDGAKVIAVDRNLKAAQETVQELGSERSAALEV--DVSSAQ 68
            ||.||||||.:..|||.|..|.||.|||.|:...|..:.....|..|..|..:...|  .|..|:
  Rat    31 LANKVALVTASTDGIGLAIARRLAEDGAHVVISSRKQQNVDRAVATLQGEGLSVTGVVCHVGKAE 95

  Fly    69 SVQFSVAEALKKFQQAPTIVVNSAGITRDGYLLKMPERDYDDVYGVNLKGTFLVTQAYAKAMIEQ 133
            ..:..|..|||..|....:|.|:|.....|.|:.:.|..::.|..:|:..:.::.:|...||  :
  Rat    96 DREKLVNMALKLHQGIDILVSNAAVNPFFGNLMDVTEEVWNKVLSINVTASAMMIKAVVPAM--E 158

  Fly   134 KLENGTIVNLSSIVAKMNNVGQANYAATKAGVISFTEVASKEFGKFGIRVNCILPGYIDTPMVAV 198
            |...|::|.:||:...:.......|..:|..::..|:..:.|.....|||||:.||.|.|...:|
  Rat   159 KRGGGSVVIVSSVAGFVLFPSLGPYNVSKTALLGLTKNFAAELAPKNIRVNCLAPGLIKTHFSSV 223

  Fly   199 V-PDSVKQEVV-QRCPLGRLGQPEEIAEVIAFLASPQSSYVNGAAIEVTGG 247
            : .:..::|:: :...:.|||:||:...:::||.|..:||:||..:.|.||
  Rat   224 LWKEKAREEMIKETMQIRRLGKPEDCVGIVSFLCSEDASYINGETVVVGGG 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3603	NP_001259199.1	fabG	6..248	CDD:235546	77/246 (31%)
CG3603	NP_001259199.1	BKR_SDR_c	9..248	CDD:187594	75/243 (31%)
Dhrs4	NP_695227.2	CR_SDR_c	24..279	CDD:187641	77/246 (31%)
Dhrs4	NP_695227.2	Microbody targeting signal	277..279
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000019
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X181
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910