DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3603 and Decr2

DIOPT Version :9

Sequence 1:	NP_001259199.1	Gene:	CG3603 / 31289	FlyBaseID:	FBgn0029648	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	NP_036063.1	Gene:	Decr2 / 26378	MGIID:	1347059	Length:	292	Species:	Mus musculus

Alignment Length:	254	Identity:	80/254 - (31%)
Similarity:	122/254 - (48%)	Gaps:	19/254 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 VLAGKVALVTGAGSGIGRATCRLLARDGAKVIAVDRNLK----AAQETVQELGSERSAALEVDVS 65
            :|..|||.:||.|||||.....:..|.|...:.|.|:|:    ||::.|...| :|...|.:||.
Mouse    25 LLQDKVAFITGGGSGIGFRIAEIFMRHGCHTVIVGRSLQKVTTAAKKLVAATG-KRCLPLSMDVR 88

  Fly    66 SAQSVQFSVAEALKKFQQAPTIVVNSAGITRDGYLL----KMPERDYDDVYGVNLKGTFLVTQAY 126
            ....|..:|.:||::|.:. .|::|.|.    |..|    .:....:..|..::..|||.|:...
Mouse    89 VPPEVMTAVDQALQEFGKI-NILINCAA----GNFLCPASALSFNAFKTVVDIDTIGTFNVSSVL 148

  Fly   127 AKAMIEQKLENGTIVNLSSIVAKMNNVGQANYAATKAGVISFTEVASKEFGKFGIRVNCILPGYI 191
            .|.....  ..|.|||:::.::....|.|.:..|.||.|.:.|...:.|:|...||||.:.||.|
Mouse   149 YKKFFRD--HGGVIVNITATLSMRGQVLQLHAGAAKAAVDAMTRHLAVEWGPQNIRVNSLAPGAI 211

  Fly   192 D-TPMVAVVPDSVKQEVVQRC--PLGRLGQPEEIAEVIAFLASPQSSYVNGAAIEVTGG 247
            . |..:..:..|.....::..  |:.|||...|||..:.:||||.:|||:|..:.|.||
Mouse   212 SGTEGLRRLRGSNASSKLKHFSNPIPRLGTKTEIAHSVLYLASPLASYVSGIVLVVDGG 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3603	NP_001259199.1	fabG	6..248	CDD:235546	80/253 (32%)
CG3603	NP_001259199.1	BKR_SDR_c	9..248	CDD:187594	79/250 (32%)
Decr2	NP_036063.1	TER_DECR_SDR_a	26..273	CDD:187627	80/253 (32%)
		PRK07576	26..271	CDD:236056	80/253 (32%)
		Substrate binding. /evidence=ECO:0000250	126..128		0/1 (0%)
		Microbody targeting signal. /evidence=ECO:0000250	290..292
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1710
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.940