DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3603 and DECR2

DIOPT Version :9

Sequence 1:	NP_001259199.1	Gene:	CG3603 / 31289	FlyBaseID:	FBgn0029648	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	NP_065715.1	Gene:	DECR2 / 26063	HGNCID:	2754	Length:	292	Species:	Homo sapiens

Alignment Length:	262	Identity:	82/262 - (31%)
Similarity:	120/262 - (45%)	Gaps:	35/262 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 VLAGKVALVTGAGSGIGRATCRLLARDGAKVIAVDRNLKAAQETVQELG---SERSAALEVDVSS 66
            :|..|||.:||.|||||.....:..|.|...:...|:|.......::|.   ..|...|.:||.:
Human    25 LLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRA 89

  Fly    67 AQSVQFSVAEALKKFQQAPTIVVNSAGITRDGYLL---KMPERDYDDVYGVNLKGTFLVTQA-YA 127
            ..:|..:|.:|||:|.:...::..:||    .:|.   .:....:..|..::..|||.|::. |.
Human    90 PPAVMAAVDQALKEFGRIDILINCAAG----NFLCPAGALSFNAFKTVMDIDTSGTFNVSRVLYE 150

  Fly   128 KAMIEQKLENGTIVNLSSIVAKMNNVGQA---NYAATKAGVISFTEVASKEFGKFGIRVNCILPG 189
            |...:   ..|.|||   |.|.:.|.|||   :..:.||.|.:.|...:.|:|...||||.:.||
Human   151 KFFRD---HGGVIVN---ITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPG 209

  Fly   190 YID---------TPMVAVVPDSVKQEVVQRCPLGRLGQPEEIAEVIAFLASPQSSYVNGAAIEVT 245
            .|.         .|..::   |.|   |...||.|||...|||..:.:||||.:|||.||.:...
Human   210 PISGTEGLRRLGGPQASL---STK---VTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVLVAD 268

  Fly   246 GG 247
            ||
Human   269 GG 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3603	NP_001259199.1	fabG	6..248	CDD:235546	82/261 (31%)
CG3603	NP_001259199.1	BKR_SDR_c	9..248	CDD:187594	81/258 (31%)
DECR2	NP_065715.1	TER_DECR_SDR_a	26..273	CDD:187627	82/261 (31%)
		Substrate binding	126..128		0/1 (0%)
		Microbody targeting signal. /evidence=ECO:0000250	290..292
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910