DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3603 and dhs-25

DIOPT Version :9

Sequence 1:	NP_001259199.1	Gene:	CG3603 / 31289	FlyBaseID:	FBgn0029648	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	NP_508282.2	Gene:	dhs-25 / 180486	WormBaseID:	WBGene00000988	Length:	248	Species:	Caenorhabditis elegans

Alignment Length:	244	Identity:	116/244 - (47%)
Similarity:	162/244 - (66%)	Gaps:	3/244 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 VLAGKVALVTGAGSGIGRATCRLLARDGAKVIAVDRNLKAAQETVQEL-GSERSAALEVDVSSAQ 68
            :|.|::|:|||..||||:|..:.||:.||:|:..|.:...|..|.:.| .|:..::...|||:|.
Worm     4 LLGGRIAVVTGGASGIGKAISQTLAKHGARVVVADLDSGNAAATAKALPASQSHSSFACDVSNAD 68

  Fly    69 SVQFSVAEALKKFQQAPTIVVNSAGITRDGYLLKMPERDYDDVYGVNLKGTFLVTQAYAKAMIEQ 133
            ||: .::|.:|.. ..|:|:||.||||:|..||||.:..:|.|..|||.|.|.|:||:.||.::.
Worm    69 SVK-GLSEHVKSL-GTPSILVNCAGITKDSTLLKMKQEQWDSVIKVNLTGVFHVSQAFVKASVDN 131

  Fly   134 KLENGTIVNLSSIVAKMNNVGQANYAATKAGVISFTEVASKEFGKFGIRVNCILPGYIDTPMVAV 198
            .....:|:|:||||.||.|.||.||||||||||.||:.|:||..|..:|||.:|||:|.|||...
Worm   132 NNHPLSIINVSSIVGKMGNFGQTNYAATKAGVIGFTKSAAKELAKKNVRVNAVLPGFIKTPMTEA 196

  Fly   199 VPDSVKQEVVQRCPLGRLGQPEEIAEVIAFLASPQSSYVNGAAIEVTGG 247
            :|.:|..|:.:..|:||:|:.||||..:.:|||..||||.||.:|||||
Worm   197 MPPTVLAEICKGIPMGRMGEAEEIANSVLYLASDLSSYVTGATLEVTGG 245

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3603	NP_001259199.1	fabG	6..248	CDD:235546	116/243 (48%)
CG3603	NP_001259199.1	BKR_SDR_c	9..248	CDD:187594	114/240 (48%)
dhs-25	NP_508282.2	fabG	4..248	CDD:235546	116/244 (48%)
dhs-25	NP_508282.2	BKR_SDR_c	8..245	CDD:187594	112/238 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	203	1.000	Domainoid score	I1732
eggNOG	1	0.900	-	-		E2759_KOG1200
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H56588
Inparanoid	1	1.050	214	1.000	Inparanoid score	I2344
Isobase	1	0.950	-	0.878984	Normalized mean entropy	S1824
OMA	1	1.010	-	-		QHG49380
OrthoDB	1	1.010	-	-		D1226147at2759
OrthoFinder	1	1.000	-	-		FOG0000019
OrthoInspector	1	1.000	-	-		otm14129
orthoMCL	1	0.900	-	-		OOG6_100272
Panther	1	1.100	-	-	LDO	PTHR42760
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1710
SonicParanoid	1	1.000	-	-		X181
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.820