DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12498 and Rtf1

DIOPT Version :9

Sequence 1:	NP_570030.1	Gene:	CG12498 / 31272	FlyBaseID:	FBgn0040356	Length:	261	Species:	Drosophila melanogaster
Sequence 2:	NP_084388.2	Gene:	Rtf1 / 76246	MGIID:	1309480	Length:	715	Species:	Mus musculus

Alignment Length:	197	Identity:	54/197 - (27%)
Similarity:	93/197 - (47%)	Gaps:	20/197 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 QRSRHVRRPAAEIVRELRNLRASPLRIDDENE-------------------SWVNGYEKPPTPDL 49
            :|.:...| .||::.:.:.|:.|.:..|||.|                   ......|:.|....
Mouse   293 EREKRKNR-TAELLAKKQPLKTSEVYSDDEEEEDDDKSSEKSDRSSRTSSSDEEEEKEEIPPKSQ 356

  Fly    50 PVTSRDQLELLRLSRHRIGLLLVRPAFEQAVTGCFVRVNVSGQGELPDHRIAEVLGICELDFGYK 114
            ||:..::|..:|||||::......|.|.:.|||||||:.:......|.:|:||:.|:.|....|:
Mouse   357 PVSLPEELNRVRLSRHKLERWCHMPFFAKTVTGCFVRIGIGNHNSKPVYRVAEITGVVETAKVYQ 421

  Fly   115 VEQIPTNVALRLRYDDLEMQHEINDVSNLNFTQEEFELWRDNCVNQAISPPTTHILTRKKVELYN 179
            :....||..|:||:.:.:....:..|||..||:.||..|::...:..:..||...:.:|::.:..
Mouse   422 LGGTRTNKGLQLRHGNDQRVFRLEFVSNQEFTESEFMKWKEAMFSAGMQLPTLDEINKKELSIKE 486

  Fly   180 AL 181
            ||
Mouse   487 AL 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12498	NP_570030.1	Plus3	51..157	CDD:197843	36/105 (34%)
Rtf1	NP_084388.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	28..218
		COG5296	194..628	CDD:227615	54/197 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	233..362		14/69 (20%)
		Plus-3	364..462	CDD:281165	35/97 (36%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	632..654
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	679..715
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5296
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003630
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810