Protein Alignment w and PDR12

DIOPT Version :10

• Sequence 1: NP_476787.1
• Gene: w / 31271
• FlyBaseID: FBgn0003996
• Length: 687
• Species: Drosophila melanogaster
• Sequence 2: NP_015267.1
• Gene: PDR12 / 856049
• SGDID: S000005979
• Length: 1511
• Species: Saccharomyces cerevisiae
• Alignment Length: 623
• Identity: 175/623 - (28%)
• Similarity: 274/623 - (43%)
• Gaps: 93/623 - (14%)

  Fly    64 LAENLTYAWHNMDIFGAVNQPGSGWRQLVNRTRGLFCNERHIPAPRKHLLKNVCGVAYPGELLAV 128
            :||...:.|:::|    ...|..|                   |.|| ||.:|.|...||::.|:
Yeast   836 IAEKDVFTWNHLD----YTIPYDG-------------------ATRK-LLSDVFGYVKPGKMTAL 876

  Fly   129 MGSSGAGKTTLLNALAFRSPQGIQVSPSGMRLLNGQPVDAKEMQARCAYVQQDDLFIGSLTAREH 193
            ||.||||||||||.||.|...|:   .:|..|:|.:|:.| .....|.||.|.|..:..|:.||.
Yeast   877 MGESGAGKTTLLNVLAQRINMGV---ITGDMLVNAKPLPA-SFNRSCGYVAQADNHMAELSVRES 937

  Fly   194 LIFQAMVRMPRHLTYRQRVARVDQVIQELSLSKCQHTIIGVPGRVKGLSGGERKRLAFASEALTD 258
            |.|.|.:|....:...::...|:::|..|.:......::|..||  ||:..:||:|:...|.:..
Yeast   938 LRFAAELRQQSSVPLEEKYEYVEKIITLLGMQNYAEALVGKTGR--GLNVEQRKKLSIGVELVAK 1000

  Fly   259 PPLLI-CDEPTSGLDSFTAHSVVQVLKKLSQKGKTVILTIHQPSSELFELFDKILLMAEG--RVA 320
            |.||: .|||||||||.:|.|:||.::.|:..|::::.||||||:.|||.||::||:.:|  .|.
Yeast  1001 PSLLLFLDEPTSGLDSQSAWSIVQFMRALADSGQSILCTIHQPSATLFEQFDRLLLLKKGGKMVY 1065

  Fly   321 F--LGTPSEAV--DFFSYVGAQCPTNYNPADFYVQVLAVVPGREIESRDRIAKICDNFAIS---K 378
            |  :|..||.:  .|....|.:|..:.|||::.:..:.......:.|...     |.:..|   .
Yeast  1066 FGDIGPNSETLLKYFERQSGMKCGVSENPAEYILNCIGAGATASVNSDWH-----DLWLASPECA 1125

  Fly   379 VAR-DMEQLLATKNLEKPLEQPENGYTYKATWFMQFRAVLWRSWLSVLKEPLLVKVRLIQTTMVA 442
            .|| ::|:|..|.......:.||....:.|::..|.:.||.|:.|...:.|:.::.:..:....|
Yeast  1126 AARAEVEELHRTLPGRAVNDDPELATRFAASYMTQIKCVLRRTALQFWRSPVYIRAKFFECVACA 1190

  Fly   443 ILIGLIFLGQQLTQVGVMNINGAIFLFLTNMTFQNVFATINVFTSELPVF---------MREARS 498
            :.:||.::|...:..|.:....:||:.|.     ...|.||    :|.||         :|||.|
Yeast  1191 LFVGLSYVGVNHSVGGAIEAFSSIFMLLL-----IALAMIN----QLHVFAYDSRELYEVREAAS 1246

  Fly   499 RLYRCDTYFL--------GKTIAELPLFLTV--PLVFTAIAYPMIGLRAGVLHFFNCLALVTLVA 553
            ..:......|        ..|:.:...|:..  |..|:..|     ..||...||    .|.:..
Yeast  1247 NTFHWSVLLLCHAAVENFWSTLCQFMCFICYYWPAQFSGRA-----SHAGFFFFF----YVLIFP 1302

  Fly   554 NVSTSFGYLISCASSSTSMALSVGPPVIIPFLLFGGFFLNSGSVPVYLKWLSY-LSWFRYANEGL 617
            ....::|..|...|.....|..:...:....|||.|.......:|.:.:.|.| :|.|.|..:.|
Yeast  1303 LYFVTYGLWILYMSPDVPSASMINSNLFAAMLLFCGILQPREKMPAFWRRLMYNVSPFTYVVQAL 1367

  Fly   618 LI----NQWADVEPGEISCTSSNTTCPSSGKVILETLN 651
            :.    |:.....|.|.     |...|.|||...|.|:
Yeast  1368 VTPLVHNKKVVCNPHEY-----NIMDPPSGKTCGEFLS 1400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
w	NP_476787.1	3a01204	68..687	CDD:273361	173/619 (28%)
PDR12	NP_015267.1	3a01205	89..1468	CDD:273362	175/623 (28%)