Protein Alignment w and PDR11

DIOPT Version :10

• Sequence 1: NP_476787.1
• Gene: w / 31271
• FlyBaseID: FBgn0003996
• Length: 687
• Species: Drosophila melanogaster
• Sequence 2: NP_012252.1
• Gene: PDR11 / 854802
• SGDID: S000001275
• Length: 1411
• Species: Saccharomyces cerevisiae
• Alignment Length: 679
• Identity: 174/679 - (25%)
• Similarity: 270/679 - (39%)
• Gaps: 166/679 - (24%)

  Fly    44 NYGTLRPPSPPEDSGSGSGQLAENLTYAWHNMDIFGAVNQPGS-------------------GWR 89
            |.|...|.:|..:..:.|..:..    ..|..|....:..|..                   .|:
Yeast   694 NDGVCTPKTPIANFSTSSSSVPS----VSHQYDTDYNIKHPDETVNNHTKESVAMETQKHVISWK 754

  Fly    90 QLVNRTRGLFCNERHIPAPRKHLLKNVCGVAYPGELLAVMGSSGAGKTTLLNALAFRSPQGIQVS 154
            . :|.|.|           .|.|:.:..|....| |.|:||.||||||||||.|:.|:..|:
Yeast   755 N-INYTIG-----------DKKLINDASGYISSG-LTALMGESGAGKTTLLNVLSQRTESGV--- 803

  Fly   155 PSGMRLLNGQP---VDAKEMQARCAYVQQDDLFIGSLTAREHLIFQAMVRMPRHLTYRQRVARVD 216
            .:|..|::|||   :||  .:....:|||.|:.:..||.||.|....::|......|...|:
Yeast   804 VTGELLIDGQPLTNIDA--FRRSIGFVQQQDVHLELLTVRESLEISCVLRGDGDRDYLGVVS--- 863

  Fly   217 QVIQELSLSKCQHTIIGVPGR--VKGLSGGERKRLAFASEALTDPPLLI-CDEPTSGLDSFTAHS 278
                         .::.:|..  |..||..:||.|:...|.:|.|.||: .||||||||:..|.:
Yeast   864 -------------NLLRLPSEKLVADLSPTQRKLLSIGVELVTKPSLLLFLDEPTSGLDAEAALT 915

  Fly   279 VVQVLKKLSQKGKTVILTIHQPSSELFELFDKI-LLMAEGRVAFLGTPSEAVDFFSYVGAQCPTN 342
            :||.|||||.:|:.::.||||||..:...||.| ||...|...:.|:...|.|:|  |.......
Yeast   916 IVQFLKKLSMQGQAILCTIHQPSKSVISYFDNIYLLKRGGECVYFGSLPNACDYF--VAHDRRLT 978

  Fly   343 Y-----NPADFYVQVLAV----VPGREIESRDRIAKICDNFAISK-------------------V 379
            :     |||||.:.|:..    :|..:.| :...:||.:..:..|                   |
Yeast   979 FDREMDNPADFVIDVVGSGSTNIPMDDAE-KPTSSKIDEPVSYHKQSDSINWAELWQSSPEKVRV 1042

  Fly   380 ARDMEQLLATKNLEKPLEQPENGYTYKA------TWFMQFRAVLWRSWLSVLKEPLLVKVRLIQT 438
            |.|:  ||    ||:  |..::|..:..      ::..|.:.:..|.::...::...|..:....
Yeast  1043 ADDL--LL----LEE--EARKSGVDFTTSVWSPPSYMEQIKLITKRQYICTKRDMTYVFAKYALN 1099

  Fly   439 TMVAILIGLIFLGQQLTQVGVMNING---AIFLF---------LTNMTFQNVFATINVFTSELPV 491
            ....:.||..|...:      .||||   ||||.         |.|........:..|:.:
Yeast  1100 AGAGLFIGFSFWRTK------HNINGLQDAIFLCFMMLCVSSPLINQVQDKALQSKEVYIA---- 1154

  Fly   492 FMREARSRLYRCDTYFLGKTIAELPLFLTVPLVFTAIAYPMIGLR-----AGVLHFFNCLALVTL 551
              |||||..|......:.:||.||||.::...:|....|...|..     |||. :.|.:    |
Yeast  1155 --REARSNTYHWTVLLIAQTIVELPLAISSSTLFFLCCYFCCGFETSARVAGVF-YLNYI----L 1212

  Fly   552 VANVSTSFG-YLISCASSSTSMALSVG---------PPVIIPFLLFGGFFLNSGSVPVYLKWLSY 606
            .:....||| :|:..|....:.|:.|.         ..|:.|:.||..|:       .::..:|.
Yeast  1213 FSMYYLSFGLWLLYSAPDLQTAAVFVAFLYSFTASFCGVMQPYSLFPRFW-------TFMYRVSP 1270

  Fly   607 LSWFRYANEGLLINQWADVEPGEISCTSS 635
            .::|......||::.      .|::|::|
Yeast  1271 YTYFIETFVSLLLHD------REVNCSTS 1293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
w	NP_476787.1	3a01204	68..687	CDD:273361	169/655 (26%)
PDR11	NP_012252.1	3a01205	56..1381	CDD:273362	174/679 (26%)