DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment w and ABCG10

DIOPT Version :9

Sequence 1:	NP_476787.1	Gene:	w / 31271	FlyBaseID:	FBgn0003996	Length:	687	Species:	Drosophila melanogaster
Sequence 2:	NP_175734.1	Gene:	ABCG10 / 841761	AraportID:	AT1G53270	Length:	590	Species:	Arabidopsis thaliana

Alignment Length:	604	Identity:	170/604 - (28%)
Similarity:	276/604 - (45%)	Gaps:	92/604 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   110 KHLLKNVCGVAYPGELLAVMGSSGAGKTTLLNALAFRSPQGIQVSPSGMRLLNGQPVDAKEMQAR 174
            |.:||:|...|...|:.|:.|.|||||||||..||.:...|   ..||..|:||:|:|..|.:..
plant    48 KVILKDVSCDARSAEITAIAGPSGAGKTTLLEILAGKVSHG---KVSGQVLVNGRPMDGPEYRRV 109

  Fly   175 CAYVQQDDLFIGSLTAREHLIFQAMVRMPRHLTYRQ-RVARVDQVIQELSLSKCQHTIIGVPGRV 238
            ..:|.|:|.....||.:|.|.:.|::|:.   |.|: ..|:|.::||||.|.....:.|| .|..
plant   110 SGFVPQEDALFPFLTVQETLTYSALLRLK---TKRKDAAAKVKRLIQELGLEHVADSRIG-QGSR 170

  Fly   239 KGLSGGERKRLAFASEALTDPPLLICDEPTSGLDSFTAHSVVQVLKKLS-QKGKTVILTIHQPSS 302
            .|:|||||:|::...|.:.||.:::.|||||||||.:|..||.:||.:: ::|||::||||||..
plant   171 SGISGGERRRVSIGVELVHDPNVILIDEPTSGLDSASALQVVTLLKDMTIKQGKTIVLTIHQPGF 235

  Fly   303 ELFELFDKILLMAEGRVAFLGTPSEAVDFFSYVGAQCPTNYNPADFYVQVLAVVPGREIESRDRI 367
            .:.|..|:|:|::.|.|...|:.........:.|.|.|...|..::.:.:...:.....:|...|
plant   236 RILEQIDRIVLLSNGMVVQNGSVYSLHQKIKFSGHQIPRRVNVLEYAIDIAGSLEPIRTQSCREI 300

  Fly   368 AKICDNFAISKVARDMEQLLATKNLEKPLEQPENGYTYKATW---------------------FM 411
            :  |                               |.:..||                     ..
plant   301 S--C-------------------------------YGHSKTWKSCYISAGGELHQSDSHSNSVLE 332

  Fly   412 QFRAVLWRSWLSVLKEPLLVKVRLIQTTMVAILIGLIFL--GQQLTQVGVMNINGAIFLFLTNMT 474
            :.:.:..||..::.:...|...|.:|.::..:::|.|:|  |.|..:..|:..  ..|.|:....
plant   333 EVQILGQRSCKNIFRTKQLFTTRALQASIAGLILGSIYLNVGNQKKEAKVLRT--GFFAFILTFL 395

  Fly   475 FQNVFATINVFTSELPVFMREARSRLYRCDTYFLGKTIAELPLFLTVPLVFTAIAYPMIGLRA-- 537
            ..:....:.:|..:..:.|||...|.||..:|.|..|:..:|..|.:.::|....|.::|||.
plant   396 LSSTTEGLPIFLQDRRILMRETSRRAYRVLSYVLADTLIFIPFLLIISMLFATPVYWLVGLRREL 460

  Fly   538 -GVLHFFNCLALVTLVANVSTSFGYLISCASSSTSMALSVGPPVIIPFLLFGGFFLNSGSVPVYL 601
             |.|:|...:.:|.|::|   ||....|....:..|..||...::..|.||.|:|:....:|||.
plant   461 DGFLYFSLVIWIVLLMSN---SFVACFSALVPNFIMGTSVISGLMGSFFLFSGYFIAKDRIPVYW 522

  Fly   602 KWLSYLSWFRYANEGLLINQWADVEPGEISCTSSNTTCPSSGKVILETLNFSAADLPLDYVGLAI 666
            :::.|||.|:|..|.|:||::                   .|.|.|:..:...:....:...:|.
plant   523 EFMHYLSLFKYPFECLMINEY-------------------RGDVFLKQQDLKESQKWSNLGIMAS 568

  Fly   667 LIVSFRVLAYLALRLRARR 685
            .||.:|||.:..|..|..|
plant   569 FIVGYRVLGFFILWYRCYR 587

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
w	NP_476787.1	3a01204	68..687	CDD:273361	170/604 (28%)
ABCG10	NP_175734.1	3a01204	27..589	CDD:273361	170/604 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48041
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	7	6.880