DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment w and ABCG9

DIOPT Version :9

Sequence 1:	NP_476787.1	Gene:	w / 31271	FlyBaseID:	FBgn0003996	Length:	687	Species:	Drosophila melanogaster
Sequence 2:	NP_194472.3	Gene:	ABCG9 / 828850	AraportID:	AT4G27420	Length:	638	Species:	Arabidopsis thaliana

Alignment Length:	664	Identity:	197/664 - (29%)
Similarity:	331/664 - (49%)	Gaps:	85/664 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 FGQAKNYGTLRPPSPPEDSGSGSGQLAENLTYAWHNMDIFGAVNQPGSGWRQLVNRTRGLFCNER 103
            |.:|.|..||:               .|||.|.....|..|                    |..:
plant    28 FKKANNPVTLK---------------FENLVYTVKLKDSQG--------------------CFGK 57

  Fly   104 HIPAPRKHLLKNVCGVAYPGELLAVMGSSGAGKTTLLNALAFRSPQGIQVSPSGMRLLNGQPVDA 168
            :.....:.:||.:.|:..|||:||::|.||:|||:||.||..|..:| :...:|....|.:|: :
plant    58 NDKTEERTILKGLTGIVKPGEILAMLGPSGSGKTSLLTALGGRVGEG-KGKLTGNISYNNKPL-S 120

  Fly   169 KEMQARCAYVQQDDLFIGSLTAREHLIFQAMVRMPRHLTYRQRVARVDQVIQELSLSKCQHTIIG 233
            |.::....:|.|||....:||..|.|:|.|::|:|.....::::.:...|:.||.|.:|:.||||
plant   121 KAVKRTTGFVTQDDALYPNLTVTETLVFTALLRLPNSFKKQEKIKQAKAVMTELGLDRCKDTIIG 185

  Fly   234 VPGRVKGLSGGERKRLAFASEALTDPPLLICDEPTSGLDSFTAHSVVQVLKKLSQKGKTVILTIH 298
            .| .::|:|||||||::...|.|.:|.||..|||||||||.||..:|.:|.:|::.|:||:.|||
plant   186 GP-FLRGVSGGERKRVSIGQEILINPSLLFLDEPTSGLDSTTAQRIVSILWELARGGRTVVTTIH 249

  Fly   299 QPSSELFELFDKILLMAEGRVAFLGTPSEAVDFFSYVG-AQCPTNYNPADFYVQVLAVVPGREIE 362
            ||||.||.:|||:||::||...:.|..|.|:|:|:.|| :......||:||.:.:...|...|.:
plant   250 QPSSRLFYMFDKLLLLSEGNPVYFGLGSNAMDYFASVGYSPLVERINPSDFLLDIANGVGSDESQ 314

  Fly   363 SRDRI-AKICDNFAISKVARDMEQLLATKNL-EKPLEQPE---NGY-TYKATWFMQFRAVLWRSW 421
            ..:.: |.:...:..:.:...:.::....:| .||.|...   |.| .:..||:.|| .||.:..
plant   315 RPEAMKAALVAFYKTNLLDSVINEVKGQDDLCNKPRESSRVATNTYGDWPTTWWQQF-CVLLKRG 378

  Fly   422 LSVLKEPLLVKVRLIQTTMVAILIGLIFLGQQLT----QVGVMNINGAIFLFLTNMTFQNVFATI 482
            |...:......:::.|..:|:.|.||::...:::    |:|::....:.:.|..  .||.:|
plant   379 LKQRRHDSFSGMKVAQIFIVSFLCGLLWWQTKISRLQDQIGLLFFISSFWAFFP--LFQQIF--- 438

  Fly   483 NVFTSELPVFMREARSRLYRCDTYFLGKTIAELPLFLTVPLVFTAIAYPMIGLRAGVLHFFNCLA 547
             .|..|..:..:|..|.:||...|||.:.:.:||:.|.:|..|..|.|.|.||...:.:||..|.
plant   439 -TFPQERAMLQKERSSGMYRLSPYFLSRVVGDLPMELILPTCFLVITYWMAGLNHNLANFFVTLL 502

  Fly   548 LVTLVANVSTSFGYLISCASSSTSMALSVGPPVIIPFLLFGGFFLNSGSVPVYLKWLSYLSWFRY 612
            ::.:...||...|..:.........|.::|..:::.|||.||:::.  .|||::.|:.|:|...|
plant   503 VLLVHVLVSGGLGLALGALVMDQKSATTLGSVIMLTFLLAGGYYVQ--HVPVFISWIKYVSIGYY 565

  Fly   613 ANEGLLINQWA--DVEPGEISCTSSNTTCPSSGKVILETLNFSAADLPLDYVG----------LA 665
            ..:.|::.|:.  ::.|           |..:||:.....:|..    :.::|          |.
plant   566 TYKLLILGQYTANELYP-----------CGDNGKLRCHVGDFEG----IKHIGFNSGLVSALALT 615

  Fly   666 ILIVSFRVLAYLAL 679
            .::|.:||:||:||
plant   616 AMLVVYRVIAYIAL 629

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
w	NP_476787.1	3a01204	68..687	CDD:273361	190/635 (30%)
ABCG9	NP_194472.3	PLN03211	19..632	CDD:215634	197/664 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	1	1.000	-	-		otm2959
orthoMCL	1	0.900	-	-		OOG6_100076
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.680