DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment w and ABCG43

DIOPT Version :9

Sequence 1:	NP_476787.1	Gene:	w / 31271	FlyBaseID:	FBgn0003996	Length:	687	Species:	Drosophila melanogaster
Sequence 2:	NP_680694.3	Gene:	ABCG43 / 827189	AraportID:	AT4G15236	Length:	1390	Species:	Arabidopsis thaliana

Alignment Length:	632	Identity:	169/632 - (26%)
Similarity:	301/632 - (47%)	Gaps:	102/632 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   106 PAPRK-HLLKNVCGVAYPGELLAVMGSSGAGKTTLLNALAFRSPQG-----IQVSPSGMRLLNGQ 164
            |..:| .||.:|.|...||.|.|:||.|||||||||:.|:.|..:|     |:|         |.
plant   810 PQGKKLQLLSDVTGAFKPGVLTALMGVSGAGKTTLLDVLSGRKTRGDIKGQIEV---------GG 865

  Fly   165 PVDAKEMQARCA-YVQQDDLFIGSLTAREHLIFQAMVRMPRHLTYRQRVARVDQVIQELSLSKCQ 228
            .|..::..:|.: |.:|.|:...:||.:|.|.:.|.:|:|.:::...:.|.|::|::.:.|.:.:
plant   866 YVKVQDTFSRVSGYCEQFDIHSPNLTVQESLKYSAWLRLPCNISSETKSAIVNEVLETIELEEIK 930

  Fly   229 HTIIGVPGRVKGLSGGERKRLAFASEALTDPPLLICDEPTSGLDSFTAHSVVQVLKKLSQKGKTV 293
            .:::|||| :.|::..:||||..|.|.:::|.::..||||:|||:..|..|::.:|.:::.|:||
plant   931 DSLVGVPG-ISGVTAEQRKRLTIAVELVSNPSIIFMDEPTTGLDARAAAIVMRAVKNIAETGRTV 994

  Fly   294 ILTIHQPSSELFELFDKILLMAE-GRVAFLGT----PSEAVDFFSYVGA--QCPTNYNPADFYVQ 351
            :.||||||.::||.||:::||.. |::.:.|.    .|:.:::|..:..  :...|.|||.:.:.
plant   995 VCTIHQPSIDIFEAFDELILMKNGGKIIYYGPLGQHSSKVIEYFMSIPGVPKLKENSNPATWILD 1059

  Fly   352 VLAVVPGREIESRDR----IAKICDNFAISK-----------VARDMEQLLATKNLEKPLEQPEN 401
            :.:.      .|.|:    :|.|.:...:.|           .:...|:|:.:..
plant  1060 ITSK------SSEDKLGVDLAHIYEESTLFKENKMVIEQTRCTSLGSERLILSSR---------- 1108

  Fly   402 GYTYKATWFMQFRAVLWRSWLSVLKEPLLVKVRLIQTTMVAILIGLIFLGQQLTQVG----VMNI 462
               |..|.:.||:|.||:..||..:.|.....|:|......:|.|::|| |:..::.    :.|:
plant  1109 ---YAQTSWEQFKACLWKQHLSYWRNPSYNLTRIIFMCFTCMLCGILFL-QKAKEINNQQDLFNV 1169

  Fly   463 NGAIFLFLTNMTFQNVFATINVFTSELPVFMREARSRLYRCDTYFLGKTIAELPLFLTVPLVFTA 527
            .|::|..:......|....|....:|..||.||..||:|....|.|.:.:.|:|..|...:::..
plant  1170 FGSMFTVVLFSGINNCSTVIFCVATERNVFYRERFSRMYNPWAYSLAQVLVEIPYSLFQSIIYVI 1234

  Fly   528 IAYPMIGLRAGVLHFFNCLALVTLVANVSTSFGYLISCASSSTSMALSVGPPVIIPFLLFGGFFL 592
            |.|||:|....|...|.....:.....:...||.|:...:.:..:|.::.........||.|:.:
plant  1235 IVYPMVGYHWSVYKVFWSFYSIFCSLLIFNYFGMLLVVVTPNVHIAFTLRSSFYAIVNLFAGYVM 1299

  Fly   593 NSGSVPVYLKWLSYLSWFRYANEGLLINQWADVEP-----GEISCTSSNTTCPSSGKVILETLNF 652
            ...::|.:..|:.|||...:...|||.:|:.|:|.     ||....|:          .||
plant  1300 PKPNIPRWWIWMYYLSPTSWVLNGLLTSQYGDMEKEILAFGEKKKVSA----------FLE---- 1350

  Fly   653 SAADLPLDYVG--------LAILIVSFRVL-----AYLALRLRARRK 686
                   ||.|        :|:::::|.:|     |:...:|..::|
plant  1351 -------DYFGYRYDSLALVAVVLIAFPILLASLFAFFIGKLNFQKK 1390

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
w	NP_476787.1	3a01204	68..687	CDD:273361	169/632 (27%)
ABCG43	NP_680694.3	AAA	13..1390	CDD:333001	168/630 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	4	3.870