Protein Alignment w and Abca6

DIOPT Version :9

• Sequence 1: NP_476787.1
• Gene: w / 31271
• FlyBaseID: FBgn0003996
• Length: 687
• Species: Drosophila melanogaster
• Sequence 2: NP_671751.2
• Gene: Abca6 / 76184
• MGIID: 1923434
• Length: 1624
• Species: Mus musculus
• Alignment Length: 717
• Identity: 143/717 - (19%)
• Similarity: 264/717 - (36%)
• Gaps: 206/717 - (28%)

  Fly    92 VNRTRGLFCNERHIPAPRKHLLKNVCGVAYPGELLAVMGSSGAGKTTLLNALAFRSPQGIQVSPS 156
            |...:|||.:                  .|..::.|::|.|||||::|||.|:     |:.|..:
Mouse   494 VKALKGLFLD------------------IYESQITAILGHSGAGKSSLLNILS-----GLYVPTA 535

  Fly   157 GMRLLNGQPV----DAKEMQARCAYVQQDDLFIGSLTAREHLIFQAMVR--MPRHLTYRQRVARV 215
            |...:..:.:    |.||::.......|.::...:||.:|:|...|.::  :|:.:.     ..|
Mouse   536 GSVTVYNKNLSDMQDLKEIRKAIGVCPQHNVQFDALTVKENLTLFAKIKGILPQDVE-----QEV 595

  Fly   216 DQVIQELSLSKCQHTIIGVPGRVKGLSGGERKRLAFASEALTDPPLLICDEPTSGLDSFTAHSVV 280
            .|::.||.:...:..:      .:.||.|::::|.|....:.||.:|:.||||.|||.|:...:.
Mouse   596 QQILSELDMQNIRDDL------AEHLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDPFSRQRIW 654

  Fly   281 QVLKKLSQKGKTVILTIHQPSSELFELFDKILLMAEGRVAFLGTP-----------------SEA 328
            ..||:  ::...|||...|...|...|.|:.:|:|.|.:...|:.                 .|.
Mouse   655 GFLKE--RRADHVILFSTQFMDEADILADRKVLIANGALKCTGSSVFLKRKWGLGYHLSLFMDET 717

  Fly   329 VD---FFSYVGAQCPTNYNPADFYVQVLAVVP------------------GREIESRD-RIAKIC 371
            .|   ..|::....|.....|....:::.::|                  |:.:.|.: .::.:.
Mouse   718 CDSERLTSFINHHIPYAKLKAKTKEKLVYILPLERTSEFPEFFSDLDKYSGQGLMSYEVSMSTLN 782

  Fly   372 D-------------NFAISKVARDMEQLLATKNLEKPLEQPENGYTYKATWFMQFRAVLWRSWLS 423
            |             :|...:.|.|.|.|...:.....|.|.:...:..:.|.||..|:   :.|.
Mouse   783 DVFLNLEGEPSTKQDFEKRETATDSESLNDMEVAYPSLSQVQETVSTMSLWRMQVCAI---ARLR 844

  Fly   424 VLK-----EPLLVKVRLIQTTMVAILI------------------GLIFL-------GQQLTQVG 458
            :||     :..|:.:.|:...::.::|                  .|.||       |.:.:.:.
Mouse   845 ILKLKRERKAFLIILLLLGIALLPLVIEYVANALLEVKNNWEFKTDLYFLSPGQLPQGLRTSLLV 909

  Fly   459 VMNINGAIFLFLTNMTFQNVFATINVF-----TSELP---VFMREARSRLYR----CDTYFLGKT 511
            :.|....|..||.::..||:...::.|     |:.|.   ..:...|.:.||    |:|    |.
Mouse   910 INNTESNIEDFLQSLKHQNIVLEVDDFENRNATNSLSYNGAIIVSGRQKDYRFSAVCNT----KR 970

  Fly   512 IAELPLFLTVPLVFTAIAYPMIGLRAGVLHFFNCLALVTLVANVSTSFGYLISCASSSTSMAL-- 574
            :...|:.:.|             :..|:||..|....:.:..::.:.|..|:......|.:.:
Mouse   971 LHCFPILMNV-------------ISNGILHMLNHTQYIRIKEDIFSPFIVLVWTGIQETCLFILC 1022

  Fly   575 ---SVGPPVIIPFLLFGGFFLNSGSVPVYLK------WLSYL----SWFRYA------NEGLLIN 620
               |:.|.:.:            .||..|.|      |:|.|    .|...|      ..|:|:.
Mouse  1023 VICSLSPHIAM------------SSVSDYKKKADSQLWISGLYPSAYWCGQAVVDISLFSGMLLT 1075

  Fly   621 QWADVEPGEISCTSSNTTCPSSGKVILETLNFSAADLPLDYVGLAILIVSFRVLAYLALRLRARR 685
            .:.      .|.||.......:.:::     ||...|.|   |.|..:|   .|.|:...:..:|
Mouse  1076 SYF------TSYTSKLLNIDMTSEIV-----FSVIVLAL---GCAASLV---FLTYVISFVFGKR 1123

  Fly   686 KE 687
            |:
Mouse  1124 KK 1125

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
w	NP_476787.1	3a01204	68..687	CDD:273361	142/715 (20%)
Abca6	NP_671751.2	rim_protein	<169..1600	CDD:130324	143/717 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000