Protein Alignment w and E23

DIOPT Version :10

• Sequence 1: NP_476787.1
• Gene: w / 31271
• FlyBaseID: FBgn0003996
• Length: 687
• Species: Drosophila melanogaster
• Sequence 2: NP_524648.3
• Gene: E23 / 43895
• FlyBaseID: FBgn0020445
• Length: 1017
• Species: Drosophila melanogaster
• Alignment Length: 796
• Identity: 227/796 - (28%)
• Similarity: 364/796 - (45%)
• Gaps: 163/796 - (20%)

  Fly    23 NNGDSGAASQSCINQGFGQAKNYGTLRPPSPPEDSGSGSGQLAE---------------NLTYAW 72
            ::..|.|:|.|..:.....::...|.:...|..|:.:.|..||.               :|:|.:
  Fly   252 SSASSSASSTSSSSSSSTSSEFTHTSQTTIPSTDNLTSSNGLANIGKSILVDAKSNSPASLSYHF 316

  Fly    73 ------------HNMDIFG-------AVNQPGSGWRQLVNRTRGLFCNERHIPAPRKHLLKNVCG 118
                        ||::|..       :.|||... .||..:...:..|||.|       |.:|.|
  Fly   317 EKSAAANQQKQHHNINICNSHHPHHHSQNQPQHS-LQLTFQNLNVLHNERQI-------LSDVSG 373

  Fly   119 VAYPGELLAVMGSSGAGKTTLLNALAFRSPQGIQVSPSGMRLLNGQPVDAKEMQARCAYVQQDDL 183
            ...|.|:||:||.||:||||||:.|:     |.:...||...||.:|: .|:.:.|..||.|:::
  Fly   374 FVSPCEVLAIMGPSGSGKTTLLDCLS-----GQRHIDSGSVFLNREPL-TKKWRRRIGYVLQEEI 432

  Fly   184 FIGSLTAREHLIFQAMVRMPRHLTYRQRVARVDQVIQELSLSKCQHTIIGVPGRVKGLSGGERKR 248
            |...||.||.:::.|::|:|..:...:::.:||.:::.|.|..||.|..| ....:||||||:||
  Fly   433 FFPQLTLRETVVYTALLRLPESMPRAEKMRQVDHILEALELGCCQQTKFG-DYLNRGLSGGEKKR 496

  Fly   249 LAFASEALTDPPLLICDEPTSGLDSFTAHSVVQVLKKLSQ-KGKTVILTIHQPSSELFELFDKIL 312
            ...|.|.||:|.|::.|||||||||.:|.|:::|||:.:| :.||:::::|||||::|.:|||:|
  Fly   497 ANIACELLTNPLLMLLDEPTSGLDSHSAISLMKVLKRYAQLEQKTIVISVHQPSSQMFHMFDKLL 561

  Fly   313 LMAEGRVAFLGTPSEAVDFFSYVGAQCPTNYNPADFYVQVLAVVPGREIESRDRIA--------- 368
            |:.:||.|:.|........|..:|.....:||||||.::.|...|  :|..:..||
  Fly   562 LLHQGRTAYFGDVQNIYRHFEDIGVTIKPHYNPADFVLEQLKSHP--DIREKLFIAAKESHGNYL 624

  Fly   369 ---------------------KICDNFAISKVARD------------MEQLLATKN---LEKPLE 397
                                 |..|:..|..:..:            .|.|..|.|   :|:..|
  Fly   625 NRNCITSSHHNQVSVSGAKGKKQADSILIDDIINNYYNQRSNRHHHQYENLHHTSNGCRVEEDEE 689

  Fly   398 QPEN-----------------------------GY-------TYKATWFMQFRAVLWRSWLSVLK 426
            ..::                             |:       :|..::..||..:..|::... |
  Fly   690 AAQHLVWCAADSQSNFSSCASSDCHSYSAGSGPGHSADDDWLSYPTSFHTQFCVLSSRNFREA-K 753

  Fly   427 EPLLVKVRLIQTTMVAILIGLIFLGQQLTQVGVMNINGAIFLFLTNMTFQNVFATINVFTSELPV 491
            ..:|.|:...||..:|::.|.|:.....|:..:.::.|.:|...|......:|..:|.|.||..|
  Fly   754 PRMLSKLNWFQTIGLALMAGAIWFQLPRTEEFLHDLQGWMFFSQTYWMLFALFGALNSFPSEREV 818

  Fly   492 FMREARSRLYRCDTYFLGKTIAELPLFLTVPLVFTAIAYPMIGLRAGVLHFFNCLALVTLVAN-- 554
            ..:|.||..||...|:|.|..|||||.:|:|.|:..|:|||:|..:..|.|   |.|:.|:.|
  Fly   819 VSKERRSGAYRLSAYYLAKMCAELPLVITLPTVYLMISYPMLGCTSLKLFF---LMLIFLLINTI 880

  Fly   555 VSTSFGYLISCASSSTSMALSVGPPVIIPFLLFGGFFLNSGSVPVYLKWLSYLSWFRYANEGLLI 619
            |:.|.|:.|.......::::::.....:...||||:.  |..:|..|.|:.|.|...||.:.:.|
  Fly   881 VAQSVGFFIGACCMDMNVSITLSALYTLATQLFGGYL--SSRIPEGLSWIRYTSMIHYAYQNMQI 943

  Fly   620 NQWADVEPGEISCTSSNTTCPSSGKV-------------ILETLNFSAADLPLDYVGLAILIVSF 671
            .::.  |...|.|.|     |||.::             ||:..| |.:.|.|:.:.|.:..:.|
  Fly   944 LEFR--EGAAIGCGS-----PSSYEICKQQSTEFIPYEEILKAQN-STSPLWLNTLILMMFFLVF 1000

  Fly   672 RVLAYLALR-LRARRK 686
            |.|.|..|| ||..:|
  Fly  1001 RCLGYAVLRFLRCPKK 1016

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
w	NP_476787.1	3a01204	68..687	CDD:273361	217/736 (29%)
E23	NP_524648.3	3a01204	363..1009	CDD:273361	202/675 (30%)