Protein Alignment w and Abcg3l2

DIOPT Version :10

• Sequence 1: NP_476787.1
• Gene: w / 31271
• FlyBaseID: FBgn0003996
• Length: 687
• Species: Drosophila melanogaster
• Sequence 2: NP_001406030.1
• Gene: Abcg3l2 / 360910
• RGDID: 1359703
• Length: 652
• Species: Rattus norvegicus
• Alignment Length: 676
• Identity: 184/676 - (27%)
• Similarity: 318/676 - (47%)
• Gaps: 115/676 - (17%)

  Fly    54 PEDSGSGSGQL-AENLTYAWHNMDIFGAVNQPGSGWRQLVNRTRGLFCNERHIPAPRKHLLKNVC 117
            ||.:.|....| .|.:..::||:.....|.   ||: .|..:||.:   ||         |.::.
  Rat    21 PETNTSDPETLTGEAVVLSFHNISYIETVQ---SGF-PLCQKTRVM---ER---------LSSIS 69

  Fly   118 GVAYPGELLAVMGSSGAGKTTLLNALAF-RSPQGIQVSPSGMRLLNGQPVDAKEMQARCAYVQQD 181
            |:..|| |.|:||.....::.||:.||. |.|.|:    ||..|:||:|..| ..:....||..:
  Rat    70 GIMGPG-LNAIMGPQDGSRSLLLDVLAARRDPSGL----SGDILVNGKPRPA-NFKCTSGYVPHN 128

  Fly   182 DLFIGSLTAREHLIFQAMVRMPRHLTYRQRVARVDQVIQELSLSKCQHTIIGVPGRVKGLSGGER 246
            |:..|::|.|::|.|.|.:|:|..:|..::..|:::|::.|.|.:.|:|        |..|...|
  Rat   129 DVVWGTVTVRDNLEFSAALRLPMTITRDEKRRRINEVLELLHLDEKQNT--------KPRSKELR 185

  Fly   247 KRLAFASEALTDPPLLICDEPTSGLDSFTAHSVVQVLKKLSQKGKTVILTIHQPSSELFELFDKI 311
            ||.:.|.|.:.|.|:|..|:||:.||..|...::.||:::|.||||:|.:|:||...:|..||.:
  Rat   186 KRTSIAVELIADHPILFLDDPTTYLDFTTTTYIISVLRRMSMKGKTIIFSINQPQYSIFRFFDSL 250

  Fly   312 LLMAEGRVAFLGTPSEAVDFFSYVGAQCPTNYNPADFYVQVL------AVVPGREIESRDRI--- 367
            .|:|.|::.|.|...:|:::|:..|       .||||::.::      ....|.|:.:.:.:
  Rat   251 SLVASGKLMFHGPARDALEYFTSAG-------YPADFFLDIINGGFCDTEEDGHEVGNYEELFER 308

  Fly   368 -----AKICDNFAISKVARD----MEQLLATKNLEK--PLEQPENGYTYKATWFMQFRAVLWRSW 421
                 .|:.:.:|.|::..|    ::|:|..:.|::  .:|      |..||.|  :..::|.::
  Rat   309 QYQATKKLVNMYAQSRLHSDTRARLDQILGQQQLDRNSAVE------TTCATPF--WHQLMWITY 365

  Fly   422 LSV--LKEPLLVKV--RLIQTTMVAILIGLI--FLGQQLTQVGVMNINGAIFLFLTNMTFQNVFA 480
            .|.  ::..|||.|  .:|:.|:.| |:|:.  ||.....:|.:.  .|.::|    :|.....|
  Rat   366 QSFKNIRGFLLVTVIQAVIKVTLAA-LVGITFQFLENDCNEVQIR--AGLLYL----LTIFQCIA 423

  Fly   481 TINV---FTSELPVFMREARSRLYRCDTYFLGKTIAELPLFLTVPLVFTAIAYPMIGLRAGVLHF 542
            ::.|   |..:...|:.|..|..||...||.||.:|:|.....:|.....|.|.:.|.|..:..|
  Rat   424 SVGVGKLFVIDRDRFLHEHTSGYYRMSCYFFGKLLADLIPRRLLPSTIVLITYFIAGGRMSMSSF 488

  Fly   543 FNCLALVTLVANVSTSFGYLISCASSSTSMALSVGP---PVIIPFLL----------FGGFFLNS 594
            |..|..|.::     .|        |.:|:.||:|.   .|.:|.||          |.|..|.|
  Rat   489 FAMLFTVMML-----DF--------SVSSLPLSIGAGKNAVAVPKLLVTIYFVFMLFFSGLSLYS 540

  Fly   595 GSVPVYLKWLSYLSWFRYANEGLLINQW------ADVEPGEISCTSSNTTCPSSGKVILETLNFS 653
            ||:|..|.|:.|.|...|..:.||.|::      .:....|:|...:...|.....:.::.::.|
  Rat   541 GSLPPQLSWIQYFSILHYGFKALLHNEFLGQNFCPEDTMEELSRCHNYVICAGEEFLAIQGIDLS 605

  Fly   654 AADLPLDYVGLAILIVSFRVLAYLAL 679
            :.....:::.||.:::....:.|:.|
  Rat   606 SWGFWENHLALACIMIILLTITYVQL 631

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
w	NP_476787.1	3a01204	68..687	CDD:273361	179/661 (27%)
Abcg3l2	NP_001406030.1	3a01204	54..632	CDD:273361	174/639 (27%)