Protein Alignment w and Abcg3

DIOPT Version :9

• Sequence 1: NP_476787.1
• Gene: w / 31271
• FlyBaseID: FBgn0003996
• Length: 687
• Species: Drosophila melanogaster
• Sequence 2: XP_017176394.1
• Gene: Abcg3 / 27405
• MGIID: 1351624
• Length: 683
• Species: Mus musculus
• Alignment Length: 697
• Identity: 189/697 - (27%)
• Similarity: 312/697 - (44%)
• Gaps: 132/697 - (18%)

  Fly    17 PSAEHLNNGDSGAASQ---------------SCINQG-----FGQAKNYGTLRPPSP-------- 53
            |:.:|.:.|...:|.|               ||.:..     ..|.|.    .||..
Mouse    22 PAPDHDHRGSKSSAEQKPEPLAPSKDPSCKSSCASSNLSPCIISQWKK----EPPEMASNNDPTV 82

  Fly    54 -----------PEDSGSGSGQLAENLTYAWHNMDIFGAVNQPGSGWRQLVNRTRGLFCNERHIPA 107
                       ||.:.|....|.|....::||:.....| |.|...|      :..:..||
Mouse    83 ISMIERHLCDLPETNTSDLKTLTEEAVLSFHNISYQETV-QSGFPLR------KKAYVIER---- 136

  Fly   108 PRKHLLKNVCGVAYPGELLAVMGSSGAGKTTLLNALAF-RSPQGIQVSPSGMRLLNGQPVDAKEM 171
                 |.|:.|:..|| |.|:||.....::.||:.||. |.|:|:    ||..|:||:|..| ..
Mouse   137 -----LSNISGIMKPG-LNAIMGPQDGSRSLLLDVLAARRDPRGL----SGDILINGKPRPA-NF 190

  Fly   172 QARCAYVQQDDLFIGSLTAREHLIFQAMVRMPRHLTYRQRVARVDQVIQELSLSKCQHTIIGVPG 236
            :....||.|:|:.:|::|.|::|.|.|.:|:|..:|..::..|:::|::.|.|:|.|:
Mouse   191 KCTSGYVPQNDVVLGTVTVRDNLEFSAALRLPVTITRDEKRRRINEVLELLHLNKEQN------- 248

  Fly   237 RVKGLSGGERKRLAFASEALTDPPLLICDEPTSGLDSFTAHSVVQVLKKLSQKGKTVILTIHQPS 301
             :|..|...|||.:.|.|.:|:.|:|..|:||:|||..|...|:.||:::|:||:|:|.:|:||.
Mouse   249 -IKPRSKELRKRTSIAMELVTEHPILFLDDPTTGLDLRTTTDVILVLRRMSKKGRTIIFSINQPQ 312

  Fly   302 SELFELFDKILLMAEGRVAFLGTPSEAVDFFSYVGAQCPTNYNPADFYVQVL---------AVVP 357
            ..:|:.||.:.|:|.|:|.|.|...:|:::|...|....::.|||||::.|:         ....
Mouse   313 YSIFKFFDSLTLVASGKVMFHGPAQDALEYFRSAGYNYESHNNPADFFLDVINGGFSNILDTEED 377

  Fly   358 GREIESRDRI--------AKICDNFAISKVARD----MEQLLATKNLEKPLEQPENGYTYKATWF 410
            |.|.:..:.:        .|:.:.:|.|.:..:    ::|||.    |:.||:.....|...|.|
Mouse   378 GHEDDKYEELFERQYQVTGKLANMYAQSPLYSETRAILDQLLG----EQKLERSSAVETTCVTPF 438

  Fly   411 M-QFRAVLWRSWLSVLKEPLLVKVRLIQTTMVAILIGLIFLGQQLTQVGVMNINGAIFLFLTNMT 474
            . |.:.::.:|:.:....|.:..::.|.|.::|..:|..|...:...:.|....|.::|......
Mouse   439 CHQLKWIICQSFKNFKGFPWVTVIQAIITVILATAVGTAFRVLKNDCIEVQMRAGLLYLLTIFQC 503

  Fly   475 FQNVFATINVFTSELPVFMREARSRLYRCDTYFLGKTIAEL-PLFLTVPLVFTAIAYPMIGLRAG 538
            ..:|.|. .:|..:...|:.|..|..||..:||.||.:||| |..|....||:.|.|.:.|::..
Mouse   504 ITSVSAG-ELFVIDRVRFLHEHTSGYYRVSSYFFGKLLAELIPRRLLPSTVFSLITYVIAGVKMS 567

  Fly   539 VLHFFNCLALVTLVANVSTSFGYLISCASSSTSMALSVGP---PVIIPFLL----------FGGF 590
            :..||..:..:.::             |.|::|:.||:|.   .|.:|.||          |.|.
Mouse   568 MKCFFTMICTIMVL-------------AYSASSLPLSIGAGENAVAVPTLLVTIYFVFMLFFSGL 619

  Fly   591 FLNSGSVPVYLKWLSYLSWFRYANEGLLINQWADVEPGEISCTSSNT 637
            .|.|||....|.|:.|.|...|....||.|::.    |:..|...||
Mouse   620 SLYSGSFLPKLSWIQYFSIPHYGFRALLHNEFL----GQNFCPEHNT 662

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
w	NP_476787.1	3a01204	68..687	CDD:273361	173/607 (29%)
Abcg3	XP_017176394.1	3a01204	137..670	CDD:273361	165/562 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100076
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.710