Protein Alignment w and Abcg2

DIOPT Version :9

• Sequence 1: NP_476787.1
• Gene: w / 31271
• FlyBaseID: FBgn0003996
• Length: 687
• Species: Drosophila melanogaster
• Sequence 2: NP_001342406.1
• Gene: Abcg2 / 26357
• MGIID: 1347061
• Length: 657
• Species: Mus musculus
• Alignment Length: 655
• Identity: 206/655 - (31%)
• Similarity: 341/655 - (52%)
• Gaps: 74/655 - (11%)

  Fly    64 LAENLTYAWHNMDIFGAVNQPGSGWRQLVNRTRGLFCNERHIPAPRKHLLKNVCGVAYPGELLAV 128
            |||....::|::.....|.   ||:  ||.:|            ..|.:|.::.|:..|| |.|:
Mouse    31 LAEGDVLSFHHITYRVKVK---SGF--LVRKT------------VEKEILSDINGIMKPG-LNAI 77

  Fly   129 MGSSGAGKTTLLNALAFR-SPQGIQVSPSGMRLLNGQPVDAKEMQARC--AYVQQDDLFIGSLTA 190
            :|.:|.||::||:.||.| .|:|:    ||..|:||.|..|   ..:|  .||.|||:.:|:||.
Mouse    78 LGPTGGGKSSLLDVLAARKDPKGL----SGDVLINGAPQPA---HFKCCSGYVVQDDVVMGTLTV 135

  Fly   191 REHLIFQAMVRMPRHLTYRQRVARVDQVIQELSLSKCQHTIIGVPGRVKGLSGGERKRLAFASEA 255
            ||:|.|.|.:|:|..:...::..|::.:|:||.|.|...:.:|.. .::|:|||||||.:...|.
Mouse   136 RENLQFSAALRLPTTMKNHEKNERINTIIKELGLEKVADSKVGTQ-FIRGISGGERKRTSIGMEL 199

  Fly   256 LTDPPLLICDEPTSGLDSFTAHSVVQVLKKLSQKGKTVILTIHQPSSELFELFDKILLMAEGRVA 320
            :|||.:|..||||:||||.||::|:.:||::|::|:|:|.:||||...:|:|||.:.|:|.|::.
Mouse   200 ITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIFSIHQPRYSIFKLFDSLTLLASGKLV 264

  Fly   321 FLGTPSEAVDFFSYVGAQCPTNYNPADFYVQVL-----AVVPGREIESR---------------- 364
            |.|...:|:::|:..|..|....|||||::.|:     ||:..||.:..
Mouse   265 FHGPAQKALEYFASAGYHCEPYNNPADFFLDVINGDSSAVMLNREEQDNEANKTEEPSKGEKPVI 329

  Fly   365 DRIAKICDNFAI-SKVARDMEQLLATKNLEKPLEQPENGYT------YKATWFMQFRAVLWRSWL 422
            :.:::...|.|| .:...:::||        |..|.:.|.:      |..::..|.|.:..||:.
Mouse   330 ENLSEFYINSAIYGETKAELDQL--------PGAQEKKGTSAFKEPVYVTSFCHQLRWIARRSFK 386

  Fly   423 SVLKEPLLVKVRLIQTTMVAILIGLIFLGQQLTQVGVMNINGAIFLFLTNMTFQNVFATINVFTS 487
            ::|..|.....:||.|.::.::||.|:...:....|:.|..|.:|...||..|.:|.| :.:|..
Mouse   387 NLLGNPQASVAQLIVTVILGLIIGAIYFDLKYDAAGMQNRAGVLFFLTTNQCFSSVSA-VELFVV 450

  Fly   488 ELPVFMREARSRLYRCDTYFLGKTIAE-LPLFLTVPLVFTAIAYPMIGLRAGVLHFFNCLALVTL 551
            |..:|:.|..|..||..:||.||.::: ||:.....::||.|.|.|:||:..|..||..:..:.:
Mouse   451 EKKLFIHEYISGYYRVSSYFFGKVMSDLLPMRFLPSVIFTCILYFMLGLKKTVDAFFIMMFTLIM 515

  Fly   552 VANVSTSFGYLISCASSSTSMALSVGPPVIIPFLLFGGFFLNSGSVPVYLKWLSYLSWFRYANEG 616
            ||..::|....|:...|..|:|..:.....:..:||.|..:|..::..:|.||.|.|..||....
Mouse   516 VAYTASSMALAIATGQSVVSVATLLMTIAFVFMMLFSGLLVNLRTIGPWLSWLQYFSIPRYGFTA 580

  Fly   617 LLINQWADVE--PG-----EISCTSSNTTCPSSGKVILETLNFSAADLPLDYVGLAILIVSFRVL 674
            |..|::...|  ||     ..:|.:|...|..:..:|.:.:..|...|..::|.||.:|:.|..:
Mouse   581 LQYNEFLGQEFCPGFNVTDNSTCVNSYAICTGNEYLINQGIELSPWGLWKNHVALACMIIIFLTI 645

  Fly   675 AYLAL 679
            |||.|
Mouse   646 AYLKL 650

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
w	NP_476787.1	3a01204	68..687	CDD:273361	203/651 (31%)
Abcg2	NP_001342406.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..24
		3a01204	46..651	CDD:273361	202/640 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831365
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H55852
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2636
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100076
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R138
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.630