Protein Alignment w and pdr1

DIOPT Version :10

• Sequence 1: NP_476787.1
• Gene: w / 31271
• FlyBaseID: FBgn0003996
• Length: 687
• Species: Drosophila melanogaster
• Sequence 2: NP_593995.1
• Gene: pdr1 / 2543363
• PomBaseID: SPAPB24D3.09C
• Length: 1396
• Species: Schizosaccharomyces pombe
• Alignment Length: 635
• Identity: 149/635 - (23%)
• Similarity: 255/635 - (40%)
• Gaps: 119/635 - (18%)

  Fly    39 FGQAKNYGTL----------RPPSPPEDSG-----SGSGQLAENLTYAWHNMDIFGAVNQPGSGW 88
            |.:.|:|..:          :|||..|...     |.:....:||...|.:::.
pombe   712 FQKRKSYSQVASSFLIEPQDKPPSQTEPDNKKVDVSTTLSTNDNLVLCWRDLNF----------- 765

  Fly    89 RQLVNRTRGLFCNERHIPAPRKHLLKNVCGVAYPGELLAVMGSSGAGKTTLLNALAFRSPQGIQV 153
             .:|.:|            .:|.:|.||.|......|.|::|.:.:||:.||..|   |.:||..
pombe   766 -TVVTKT------------SKKQILTNVSGYLKKNTLTALLGENKSGKSVLLRIL---SQRGIAG 814

  Fly   154 SPSGMRLLNGQPVDAKEMQARCAYVQQDDLFIGSLTAREHLIFQAMVRMPRHLTYRQRVARVDQV 218
            |..|...|:|.. :.|.::.|..||:::.|||...|.||.|...|.:|..:..:..::.|.|:.|
pombe   815 SVEGEITLSGLK-NPKNLRKRIGYVRKNPLFISEYTVRETLRLHAALRQSKQRSLSEQYAYVEYV 878

  Fly   219 IQELSLSKCQHTIIGVPGRVKGLSGGERKRLAFASEALTDP-PLLICDEPTSGLDSFTAHSVVQV 282
            |..|.|.:....|:|..|  ||||...::.|:.|.|....| .:|:.|||.:||||.:|..:|.:
pombe   879 IDFLGLGEVADFIVGDMG--KGLSLYHKRLLSIAVELSARPGSILLLDEPANGLDSQSAWMLVCI 941

  Fly   283 LKKLSQKGKTVILTIHQPSSELFELFDKILLM-AEGRVAFLGTP----SEAVDFFSYVGAQCPTN 342
            |:||::.|.:::.::.||||.:.||||.:|:: ..|...:..|.    |:.|::|..:......:
pombe   942 LQKLARSGLSILCSVSQPSSRILELFDMMLILDLNGNTVYYDTMGRDLSKLVNYFKRIHGTNEHS 1006

  Fly   343 YNPADFYVQVLAVVPGREIESRDRIAKICDNFAISKVARDMEQLLATKNLEKP--------LEQP 399
            .:.|||.:.                   |..|.......|.....|:.|..|.        ::.|
pombe  1007 KDTADFVLH-------------------CIQFLKQGPEFDYAGAWASTNTHKQIIEHVNFIMDNP 1052

  Fly   400 E-------NGYTYKATWFMQFRAVLWRSWLSVLKEPLLVKVRLIQTTMVAILIGLIFLGQQLTQV 457
            |       |...:..::|.|...:..|::::..::..|::.|:....:..::||..|..|   .|
pombe  1053 ELTDDDFPNETRFMTSFFFQIYKISMRNFVAYWRDSSLLRARVAFNIVAGLIIGFSFYKQ---GV 1114

  Fly   458 GVMNINGAIFLFLTNMTFQNVFATINVFTSELP--VFMREARSRLYRCDTYFLGKTIAELPLFLT 520
            ||......:|     ..:....|:.:......|  ::.|....: |..:|....:|...:..||.
pombe  1115 GVEETQNKMF-----SAYMLTVASTSTMNGLQPKFIYFRSIYEQ-YEQNTAIYSRTAFIIAFFLV 1173

  Fly   521 --------VPLVFTAIAYPMIGLRAGVLHF---------FNCLALVTLVANVSTSFGYLISCASS 568
                    ..|.|....||     :|...|         |..|.|: :.....|:.|..|:..|.
pombe  1174 EAVINCCFATLFFFGWYYP-----SGFYEFNHNIPFYGGFAWLMLM-IFTLYYTTLGIGIATISP 1232

  Fly   569 STSMALSVGPPVIIPFLLFGGFFLNSGSVPVYLKWLSYLSWFRYANEGLL 618
            |...|..:.....:....|.|.....|.:..:.||:..||.::|..||::
pombe  1233 SIGTASIISGTAFVFIQYFNGMIQLPGVIVGFWKWMDALSPYKYFLEGMI 1282

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
w	NP_476787.1	3a01204	68..687	CDD:273361	140/591 (24%)
pdr1	NP_593995.1	3a01205	40..1382	CDD:273362	149/635 (23%)