Protein Alignment w and wht-8

DIOPT Version :9

• Sequence 1: NP_476787.1
• Gene: w / 31271
• FlyBaseID: FBgn0003996
• Length: 687
• Species: Drosophila melanogaster
• Sequence 2: NP_499442.2
• Gene: wht-8 / 189976
• WormBaseID: WBGene00012925
• Length: 619
• Species: Caenorhabditis elegans
• Alignment Length: 618
• Identity: 222/618 - (35%)
• Similarity: 349/618 - (56%)
• Gaps: 54/618 - (8%)

  Fly    88 WRQLVNRTRGLFCNERHIPAPRKHLLKNVCGVAYPGELLAVMGSSGAGKTTLLNALAFRSPQGIQ 152
            ||.|...|:.           .:.||..|.|.|.|||::|:||:||||||||||.|..|:.:|:|
 Worm    36 WRNLKVTTKA-----------GRVLLNGVSGCAVPGEVIALMGASGAGKTTLLNTLLQRNLRGLQ 89

  Fly   153 VSPSGMRLLNGQPVDAKEMQARCAYVQQDDLFIGSLTAREHLIFQAMVRMPRHLTYRQRVARVDQ 217
            |  .|..|:|||.: .|.:.:..|||||:|||:|:||.:|||..||.:|:|...:...|..||::
 Worm    90 V--EGEILVNGQNI-GKGVTSVSAYVQQEDLFMGTLTVKEHLDIQAKLRLPPGTSTTARATRVNE 151

  Fly   218 VIQELSLSKCQHTIIGVPGRVKGLSGGERKRLAFASEALTDPPLLICDEPTSGLDSFTAHSVVQV 282
            |:.|:.|.|.:.:.|||||..||:||||.||||||:|.:.:||::.|||||:||||   |..:||
 Worm   152 VMNEMLLEKPRDSRIGVPGIKKGISGGEMKRLAFATEMINNPPIIFCDEPTTGLDS---HMSLQV 213

  Fly   283 LKKLSQ----KGKTVILTIHQPSSELFELFDKILLMAEGRVAFLGTPSEAVDFFSYVGAQCPTNY 343
            :|.|.|    ||||:|.||||||||:||:|||::.:|:||:||.|...||:..||..|.|.|.:.
 Worm   214 VKTLEQMALEKGKTIICTIHQPSSEVFEIFDKVVFLAQGRIAFHGAIDEAIHHFSSCGYQVPDHT 278

  Fly   344 NPADFYVQVLAVVPGREIESRDRIAKICDNFAISKVARDMEQLLATKNLEKPLEQ--------PE 400
            ||||:::..||:.|......:.|..::||.|         |:....:.|.|.::|        |.
 Worm   279 NPADYFIDTLAIKPSEAEACKSRCQELCDKF---------EKSFYNERLTKLMDQTKDVRAMTPH 334

  Fly   401 NGYTYKATWFMQFRAVLWRSWLSVLKEPLLVKVRLIQTTMVAILIGLIFLGQQLTQVGVMNINGA 465
            :..||....:    |:.:|..|..::.|.::|.:|||...:.:.||.:|.|.:..|.|:.:..||
 Worm   335 HSATYPVLLY----ALFYRYMLDNIRNPAIMKAKLIQKLFMGLFIGTLFYGLETDQDGLASYKGA 395

  Fly   466 IFLFLTNMTFQNVFATINVFTSELPVFMREARSRLYRCDTYFLGKTIAELPLFLTVPLVFTAIAY 530
            :|.:::.:|:..:|.......::.|..:||...|:|....|::.|..:.||:|....::....:|
 Worm   396 LFYYISELTYSTIFGIQAFMPADYPPLVREYDDRIYPISAYYIAKICSFLPIFTVDGIILVVSSY 460

  Fly   531 PMIGLRA--GVL--HFFNCLALVTLVANVSTSFGYLISCASSSTSMALSVGPPVIIPFLLFGGFF 591
            .::|..:  ||.  ..|.|:|:...||    :.|..:...:.|.::|::|..|::..|.|.||.|
 Worm   461 FLVGFPSDFGVFLRQIFTCMAIEWNVA----ALGIAVCATAPSYAIAVTVTGPLLTVFSLTGGLF 521

  Fly   592 LNSGSVPVYLKWLSYLSWFRYANEGLLINQWADVEPGEISCTS--SNTTCPSSGKVILETLNFSA 654
            .|...:|.::.|:.|||||||..|.|::||:...:...|:|.:  :...|..||.:.::..:|..
 Worm   522 TNIAEMPAWINWVQYLSWFRYGYESLVVNQFQHDQFANITCNANMNEQLCEKSGPIAIKNFSFDT 586

  Fly   655 ADLPLDYVGLAILIVSFRVLAYLAL--RLRARR 685
            |:|..::|.:..|.:...::.|:.|  |:.|.|
 Worm   587 ANLYTNWVAMIYLTIIIYIVGYMGLVRRVIANR 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
w	NP_476787.1	3a01204	68..687	CDD:273361	222/618 (36%)
wht-8	NP_499442.2	3a01204	22..615	CDD:273361	219/612 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2636
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100076
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R138
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.700