Protein Alignment w and Abcg8

DIOPT Version :9

• Sequence 1: NP_476787.1
• Gene: w / 31271
• FlyBaseID: FBgn0003996
• Length: 687
• Species: Drosophila melanogaster
• Sequence 2: NP_569098.2
• Gene: Abcg8 / 155192
• RGDID: 620300
• Length: 672
• Species: Rattus norvegicus
• Alignment Length: 611
• Identity: 172/611 - (28%)
• Similarity: 293/611 - (47%)
• Gaps: 79/611 - (12%)

  Fly   113 LKNVCGVAYPGELLAVMGSSGAGKTTLLNALAFRSPQGIQVSPSGMRLLNGQPVDAKEMQARCAY 177
            ::|:......|::||::||:|.|:.|||:.:..|...|  ...||...:||||...:.:|...|:
  Rat    88 IRNLSFKVRSGQMLAIIGSAGCGRATLLDVITGRDHGG--KMKSGQIWINGQPSTPQLIQKCVAH 150

  Fly   178 VQQDDLFIGSLTAREHLIFQAMVRMPRHLTYRQRVARVDQVIQELSLSKCQHTIIGVPGRVKGLS 242
            |:|.|..:.:||.||.|.|.|.:|:|:..:..||..||:.||.||.|.:|.:|.:| ...|:|:|
  Rat   151 VRQQDQLLPNLTVRETLTFIAQMRLPKTFSQAQRDKRVEDVIAELRLRQCANTRVG-NTYVRGVS 214

  Fly   243 GGERKRLAFASEALTDPPLLICDEPTSGLDSFTAHSVVQVLKKLSQKGKTVILTIHQPSSELFEL 307
            ||||:|::...:.|.:|.:||.|||||||||||||::|:.|.:|::..:.|::::|||.|::|.|
  Rat   215 GGERRRVSIGVQLLWNPGILILDEPTSGLDSFTAHNLVRTLSRLAKGNRLVLISLHQPRSDIFRL 279

  Fly   308 FDKILLMAEGRVAFLGTPSEAVDFFSYVGAQCPTNYNPADFYVQVLAVVPGREIESRDRIAKICD 372
            ||.:|||..|...:||.....|.:|:.:|..||...|||||||         ::.|.||.:|..:
  Rat   280 FDLVLLMTSGTPIYLGVAQHMVQYFTSIGYPCPRYSNPADFYV---------DLTSIDRRSKEQE 335

  Fly   373 NFAISKVARDMEQLLATKNLEKPLEQPENGYTYKAT----------------------------- 408
            ...:.|.     :|||...|||  .|..:.:.:||.
  Rat   336 VATMEKA-----RLLAALFLEK--VQGFDDFLWKAEAKSLDTGTYAVSQTLTQDTNCGTAAELPG 393

  Fly   409 WFMQFRAVLWRSWLSVLKEPLLVKVRLIQTTMVAILIGLIFLGQQLTQVGVMNINGAIFLFLTNM 473
            ...||..::.|...:..::...:.:...:..:::::||.::.|.....:..|::...:|:....:
  Rat   394 MIQQFTTLIRRQISNDFRDLPTLFIHGAEACLMSLIIGFLYYGHADKPLSFMDMAALLFMIGALI 458

  Fly   474 TFQNVFATINVFTSELPVFMREARSRLYRCDTYFLGKTIAELPLFLTVPLVFTAIAYPMIGLRAG 538
            .|..:...::...||..:...|....||....||..|.:.|||......:::....|.:..||.|
  Rat   459 PFNVILDVVSKCHSERSLLYYELEDGLYTAGPYFFAKVLGELPEHCAYVIIYGMPIYWLTNLRPG 523

  Fly   539 ----VLHF-------FNCLALVTLVANVSTSFGYLISCASSSTSMALSVGPPVIIPFLLFGGFFL 592
                :|||       |.|..:....:.:..:|.....|.::           :...|.|..||.:
  Rat   524 PELFLLHFMLLWLVVFCCRTMALAASAMLPTFHMSSFCCNA-----------LYNSFYLTAGFMI 577

  Fly   593 NSGSVPVYLKWLSYLSWFRYANEGLLINQWADVEPGEISCTS-SNTTCPSSGKVILETLNFSAAD 656
            |..::.:...|:|.:|:.|:...||:..|:    .|.|..|. .|.|....|..::..::.::.
  Rat   578 NLNNLWIVPAWISKMSFLRWCFSGLMQIQF----NGHIYTTQIGNLTFSVPGDAMVTAMDLNSH- 637

  Fly   657 LPLDYVGLAILIVS--FRVLAYLALR 680
             ||..:.|.::.:|  |..|.||:|:
  Rat   638 -PLYAIYLIVIGISCGFLSLYYLSLK 662

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
w	NP_476787.1	3a01204	68..687	CDD:273361	172/611 (28%)
Abcg8	NP_569098.2	ABCG_White	60..295	CDD:213201	86/209 (41%)
		3a01204	88..662	CDD:273361	171/609 (28%)
		ABC2_membrane	401..605	CDD:279410	40/214 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335099
Domainoid	1	1.000	92	1.000	Domainoid score	I7408
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100076
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.750