Protein Alignment w and abcg8

DIOPT Version :10

• Sequence 1: NP_476787.1
• Gene: w / 31271
• FlyBaseID: FBgn0003996
• Length: 687
• Species: Drosophila melanogaster
• Sequence 2: NP_001108041.3
• Gene: abcg8 / 100136850
• ZFINID: ZDB-GENE-050517-41
• Length: 676
• Species: Danio rerio
• Alignment Length: 656
• Identity: 188/656 - (28%)
• Similarity: 327/656 - (49%)
• Gaps: 46/656 - (7%)

  Fly    52 SPPEDS------GSGSGQL-AENLTYAWHNMDIFGAVNQPGSGWRQLVNRTRGLFCNERHIPAPR 109
            ||.|||      ..|..:| ..||.|     ::..|...|   |.:.::..:..:  |.|  :.:
Zfish    30 SPEEDSSLYFTYSGGRNELEVRNLNY-----EVDTAAQIP---WYEKLSEFKMPW--EMH--SNK 82

  Fly   110 KHLLKNVCGVAYPGELLAVMGSSGAGKTTLLNALAFRSPQGIQVSPSGMRLLNGQPVDAKEMQAR 174
            :.::|::....:.|::|||:||||.|||:||:.:..|...|..  .||..|:||:|.....::..
Zfish    83 QTVIKDLNLHVHSGQMLAVIGSSGCGKTSLLDIITCRDEGGSM--NSGEILINGKPSTRSLVKKS 145

  Fly   175 CAYVQQDDLFIGSLTAREHLIFQAMVRMPRHLTYRQRVARVDQVIQELSLSKCQHTIIGVPGRVK 239
            .|:|:|||..:..||.||.|.|.|.:|:|.:.:.:||..|||.||.||.|.:|.||.:| ...|:
Zfish   146 IAHVRQDDRLLPHLTVRETLAFVAKLRLPANFSQKQRDQRVDDVIAELRLRQCAHTRVG-NEYVR 209

  Fly   240 GLSGGERKRLAFASEALTDPPLLICDEPTSGLDSFTAHSVVQVLKKLSQKGKTVILTIHQPSSEL 304
            |:|||||:|::.|.:.|.:|.:||.|||||||||||||::|..|.:|::..:.|:|::|||.|::
Zfish   210 GVSGGERRRVSIAVQLLWNPGILILDEPTSGLDSFTAHNLVITLYRLARGNRLVLLSVHQPRSDI 274

  Fly   305 FELFDKILLMAEGRVAFLGTPSEAVDFFSYVGAQCPTNYNPADFYVQVLAV---VPGREIESRDR 366
            |:|||.::|::.|...:.|...:.|.:|:.:|..||...||:|:||.::::   .|.:|.:..::
Zfish   275 FQLFDLVVLLSSGSAVYCGQAKDMVSYFTTLGYPCPRYCNPSDYYVDLISIDRRTPEKEAQCLEK 339

  Fly   367 IAKICDNFAISKVARDMEQLLATKNLEKP-LEQPEN---GYTYKATWFM-------------QFR 414
            .:.:...| :.||..:.:.:..::....| ||.|::   ..:.|.:...             ||.
Zfish   340 ASMLAAQF-LEKVKNNEDFMWKSEVCGPPALEAPQSSVPSVSMKESVITVSKQKDQLPGKVHQFT 403

  Fly   415 AVLWRSWLSVLKEPLLVKVRLIQTTMVAILIGLIFLGQQLTQVGVMNINGAIFLFLTNMTFQNVF 479
            .::.|...:..::.:.:.|..::..::::|||.::.|.....:.:.:....:::......|..|.
Zfish   404 TLIRRQVFNDYRDLVTLVVHGLEALLMSLLIGFLYFGCTEEGLSIQDTVALLYMIGALTPFAVVL 468

  Fly   480 ATINVFTSELPVFMREARSRLYRCDTYFLGKTIAELPLFLTVPLVFTAIAYPMIGLRAGVLHFFN 544
            ..|....||..:...|....:|....||..|.:.|||......||:....|.:.||......|..
Zfish   469 DVIAKCHSERAMLYHELEDGMYSVTPYFFAKVLGELPEHCAFTLVYGVPIYWLAGLNVAPDRFLL 533

  Fly   545 CLALVTLVANVSTSFGYLISCASSSTSMALSVGPPVIIPFLLFGGFFLNSGSVPVYLKWLSYLSW 609
            ...||.|....|.|....::.|..:...:..:|..:...|.|..||.::..::.:...|.||:|:
Zfish   534 NFLLVWLTVYCSRSMALFVAAALPTLQTSSFMGNALFTVFYLTAGFVISLENMWMVASWFSYISF 598

  Fly   610 FRYANEGLLINQWADVEPGEISCTSSNTTCPSSGKVILETLNFSAADLPLDYVGLAILIVSFRVL 674
            .|:..||:|..|:...   .|..|..|.|....|..::|.:..:...|...|:.|..:.:.|.:|
Zfish   599 MRWGFEGMLQVQFRGT---RIPITIGNLTVEFDGIKVVEMMKMNQYPLFSCYLVLIAVSLVFILL 660

  Fly   675 AYLALR 680
            .||:|:
Zfish   661 YYLSLK 666

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
w	NP_476787.1	3a01204	68..687	CDD:273361	180/633 (28%)
abcg8	NP_001108041.3	None