Protein Alignment w and abcg8

DIOPT Version :9

• Sequence 1: NP_476787.1
• Gene: w / 31271
• FlyBaseID: FBgn0003996
• Length: 687
• Species: Drosophila melanogaster
• Sequence 2: NP_001108041.2
• Gene: abcg8 / 100136850
• ZFINID: ZDB-GENE-050517-41
• Length: 684
• Species: Danio rerio
• Alignment Length: 662
• Identity: 188/662 - (28%)
• Similarity: 326/662 - (49%)
• Gaps: 58/662 - (8%)

  Fly    52 SPPEDS------GSGSGQL-AENLTYAWHNMDIFGAVNQPGSGWRQLVNRTRGLFCNERHIPAPR 109
            ||.|||      ..|..:| ..||.|     ::..|...|   |.:.::..:..:  |.|  :.:
Zfish    38 SPEEDSSLYFTYSGGRNELEVRNLNY-----EVDTAAQIP---WYEKLSEFKMPW--EMH--SNK 90

  Fly   110 KHLLKNVCGVAYPGELLAVMGSSGAGKTTLLNALAFRSPQGIQVSPSGMRLLNGQPVDAKEMQAR 174
            :.::|::....:.|::|||:||||.|||:||:.:..|...|..  .||..|:||:|.....::..
Zfish    91 QTVIKDLNLHVHSGQMLAVIGSSGCGKTSLLDIITCRDEGGSM--NSGEILINGKPSTRSLVKKS 153

  Fly   175 CAYVQQDDLFIGSLTAREHLIFQAMVRMPRHLTYRQRVARVDQVIQELSLSKCQHTIIGVPGRVK 239
            .|:|:|||..:..||.||.|.|.|.:|:|.:.:.:||..|||.||.||.|.:|.||.:| ...|:
Zfish   154 IAHVRQDDRLLPHLTVRETLAFVAKLRLPANFSQKQRDQRVDDVIAELRLRQCAHTRVG-NEYVR 217

  Fly   240 GLSGGERKRLAFASEALTDPPLLICDEPTSGLDSFTAHSVVQVLKKLSQKGKTVILTIHQPSSEL 304
            |:|||||:|::.|.:.|.:|.:||.|||||||||||||::|..|.:|::..:.|:|::|||.|::
Zfish   218 GVSGGERRRVSIAVQLLWNPGILILDEPTSGLDSFTAHNLVITLYRLARGNRLVLLSVHQPRSDI 282

  Fly   305 FELFDKILLMAEGRVAFLGTPSEAVDFFSYVGAQCPTNYNPADFYVQVLAV---VPGREIESRDR 366
            |:|||.::|::.|...:.|...:.|.:|:.:|..||...||:|:||.::::   .|.:|.:..::
Zfish   283 FQLFDLVVLLSSGSAVYCGQAKDMVSYFTTLGYPCPRYCNPSDYYVDLISIDRRTPEKEAQCLEK 347

  Fly   367 IAKICDNFAISKVARDMEQLLATKNLEKP-LEQPEN----------------------GYTYKAT 408
            .:.:...| :.||..:.:.:..::....| ||.|::                      |..:
Zfish   348 ASMLAAQF-LEKVKNNEDFMWKSEVCGPPALEAPQSSVPSVSMKESVITVSKQKDQLPGKVH--- 408

  Fly   409 WFMQFRAVLWRSWLSVLKEPLLVKVRLIQTTMVAILIGLIFLGQQLTQVGVMNINGAIFLFLTNM 473
               ||..::.|...:..::.:.:.|..::..::::|||.::.|.....:.:.:....:::.....
Zfish   409 ---QFTTLIRRQVFNDYRDLVTLVVHGLEALLMSLLIGFLYFGCTEEGLSIQDTVALLYMIGALT 470

  Fly   474 TFQNVFATINVFTSELPVFMREARSRLYRCDTYFLGKTIAELPLFLTVPLVFTAIAYPMIGLRAG 538
            .|..|...|....||..:...|....:|....||..|.:.|||......||:....|.:.||...
Zfish   471 PFAVVLDVIAKCHSERAMLYHELEDGMYSVTPYFFAKVLGELPEHCAFTLVYGVPIYWLAGLNVA 535

  Fly   539 VLHFFNCLALVTLVANVSTSFGYLISCASSSTSMALSVGPPVIIPFLLFGGFFLNSGSVPVYLKW 603
            ...|.....||.|....|.|....::.|..:...:..:|..:...|.|..||.::..::.:...|
Zfish   536 PDRFLLNFLLVWLTVYCSRSMALFVAAALPTLQTSSFMGNALFTVFYLTAGFVISLENMWMVASW 600

  Fly   604 LSYLSWFRYANEGLLINQWADVEPGEISCTSSNTTCPSSGKVILETLNFSAADLPLDYVGLAILI 668
            .||:|:.|:..||:|..|:...   .|..|..|.|....|..::|.:..:...|...|:.|..:.
Zfish   601 FSYISFMRWGFEGMLQVQFRGT---RIPITIGNLTVEFDGIKVVEMMKMNQYPLFSCYLVLIAVS 662

  Fly   669 VSFRVLAYLALR 680
            :.|.:|.||:|:
Zfish   663 LVFILLYYLSLK 674

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
w	NP_476787.1	3a01204	68..687	CDD:273361	180/639 (28%)
abcg8	NP_001108041.2	3a01204	47..674	CDD:273361	182/651 (28%)
		ABCG_White	72..301	CDD:213201	95/238 (40%)
		ABC2_membrane	413..617	CDD:279410	44/203 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574375
Domainoid	1	1.000	119	1.000	Domainoid score	I5779
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100076
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.750