DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32795 and Tmem120b

DIOPT Version :9

Sequence 1:	NP_001245509.1	Gene:	CG32795 / 31270	FlyBaseID:	FBgn0040384	Length:	387	Species:	Drosophila melanogaster
Sequence 2:	NP_001258238.1	Gene:	Tmem120b / 690137	RGDID:	1584031	Length:	339	Species:	Rattus norvegicus

Alignment Length:	334	Identity:	155/334 - (46%)
Similarity:	222/334 - (66%)	Gaps:	4/334 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 IDSLKNEWEELNKEFAELESCNRRYIELLEQLHSHQQICFNEIKHQRYRMNQITTSLRQFKGPVP 67
            ::..:.||.||..||.||:..:|.|.:.||:|.:.|..|...|..|:..:..:..:|:::|....
  Rat     5 LERCEREWHELEGEFQELQETHRIYKQKLEELTALQTQCSISISKQKRHLKDLKYALQRYKCHSS 69

  Fly    68 AEDKEKVDDLHKMTLKRKAQLHEIEQSLPAKSGRYLQIILGDVNVSILNRNDKVRYKDDYEKFKL 132
            .|:.|.|..|.....:|:....::|..||.|:|.||.::||:|:|::|:...|..|||:||||||
  Rat    70 QEEAELVQQLAANIKERQNVFFDMEAYLPKKNGLYLNLVLGNVDVTLLSNQAKFAYKDEYEKFKL 134

  Fly   133 ILNVIGLIMAF-FNLIFNYRALELAFIFLLVWYYCTLTIRESILKVNGSRIKGWWRAHHFISTVA 196
            .|.:|.|:.|. ...:.:||..:..|.|||||||||||||||||..|||||||||.:||::|:..
  Rat   135 YLTIILLLGAVACRFVLHYRVTDEVFNFLLVWYYCTLTIRESILISNGSRIKGWWVSHHYVSSFL 199

  Fly   197 AGVLLVWPQGEHWQIFRMQFMYFNVYISIVQYLQFGYQKGLLYRLKALGERHNMDITIEGFHSWM 261
            :||:|.||.|..:|.||.||:.|:::.|.||:||:.||:|.||||:|||||:::|:|:|||.|||
  Rat   200 SGVMLTWPNGLIYQKFRNQFLAFSIFQSCVQFLQYYYQRGCLYRLRALGERNHLDLTVEGFQSWM 264

  Fly   262 WRGLSFLLPFLFIGYGYQAYNAWTLYKLAYSPPDAPWHVSVMSGLFLLLFVGNMATTLWVVPEKI 326
            ||||:|||||||.|:.:|.|||.||::|:.......|.|.|::..||:||:||..|||.||..|:
  Rat   265 WRGLTFLLPFLFCGHFWQLYNAVTLFELSSHEECKEWQVFVLALTFLILFLGNFLTTLKVVHAKL 329

  Fly   327 ---RERAKE 332
               |.:.|:
  Rat   330 QKNRNKTKQ 338

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32795	NP_001245509.1	TMPIT	7..329	CDD:285135	154/325 (47%)
Tmem120b	NP_001258238.1	TMPIT	9..332	CDD:285135	153/322 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353784
Domainoid	1	1.000	320	1.000	Domainoid score	I1199
eggNOG	1	0.900	-	-		E1_KOG4758
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	322	1.000	Inparanoid score	I2425
OMA	1	1.010	-	-		QHG55657
OrthoDB	1	1.010	-	-		D398151at33208
OrthoFinder	1	1.000	-	-		FOG0002380
OrthoInspector	1	1.000	-	-		otm45698
orthoMCL	1	0.900	-	-		OOG6_103806
Panther	1	1.100	-	-	O	PTHR21433
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1574
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.810