DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32795 and ints14

DIOPT Version :9

Sequence 1:	NP_001245509.1	Gene:	CG32795 / 31270	FlyBaseID:	FBgn0040384	Length:	387	Species:	Drosophila melanogaster
Sequence 2:	NP_001007939.1	Gene:	ints14 / 493315	XenbaseID:	XB-GENE-978854	Length:	518	Species:	Xenopus tropicalis

Alignment Length:	305	Identity:	62/305 - (20%)
Similarity:	111/305 - (36%)	Gaps:	83/305 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   105 IILGDVNVSILNRNDKVRYKDDYEKFKLILNVIGLIMAFFNLIFNYRALELA--FIFLLVWY--- 164
            :::.||::| :.|...|...:::::..|.::  ||.|.|.::..||: ||..  .:|..:|.
Frog     4 VVVMDVSLS-MTRPVPVEGTEEFQRKHLAVH--GLTMLFEHMATNYK-LEFTAMVVFSSLWELMV 64

  Fly   165 -----YCTL------------TIRESILKVNGSRIKGWWRAHHFISTVAAGVLLVWP-------- 204
                 |.||            |..||.|:...|.::..|.|     ::.:.::||..
Frog    65 PFTRDYNTLQEALSNIDDYDKTCLESALQGVSSVVQQEWGA-----SIPSQIVLVTDGCLGIGKG 124

  Fly   205 ----------QGEHWQIFRMQFMY-FNVYI---SIVQYLQFGYQKGLLYRLKALGERHNMDITIE 255
                      |......|.:.|.: ..:||   :.::.||.......|.||..|........||:
Frog   125 SLQHSLATLNQRNDSNRFPLPFSFPSKLYIMCMANLEELQGSDSLEYLERLIDLNNGEGQIFTID 189

  Fly   256 GFHSWMWRGLSFLLPFLFIGYGYQAYNAWTLYKLAYSPPDAPWHVSVMSGLFLLLFVGNMATTLW 320
            |         ...|..:...:|       .|..:||:    |:|.        :|..||:::.:.
Frog   190 G---------PLCLKNVQSMFG-------KLIDVAYT----PFHA--------VLKCGNLSSDVQ 226

  Fly   321 VVPEKIRERAKERYRLQSMGKSMKLRKEMKNSASDLDLSSGSKLS 365
            |.|..  |.......:..:.|::....|:.......|:||...||
Frog   227 VFPRP--EPVITDEEIDPLPKTINTDLEVVGFIDIADISSPPVLS 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32795	NP_001245509.1	TMPIT	7..329	CDD:285135	54/267 (20%)
ints14	NP_001007939.1	VWA_2	3..117	CDD:379234	28/121 (23%)
ints14	NP_001007939.1	NK	<357..489	CDD:388413
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165177586
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930