DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32795 and tmem120aa

DIOPT Version :9

Sequence 1:	NP_001245509.1	Gene:	CG32795 / 31270	FlyBaseID:	FBgn0040384	Length:	387	Species:	Drosophila melanogaster
Sequence 2:	NP_001076452.1	Gene:	tmem120aa / 100005623	ZFINID:	ZDB-GENE-070424-21	Length:	341	Species:	Danio rerio

Alignment Length:	326	Identity:	158/326 - (48%)
Similarity:	223/326 - (68%)	Gaps:	1/326 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 EWEELNKEFAELESCNRRYIELLEQLHSHQQICFNEIKHQRYRMNQITTSLRQFKGPVPAEDKEK 73
            |||:|.|::.:::..:|.|...||::...|:.|.:.|..||.::..::.||.:.||.|..||..|
Zfish    14 EWEDLEKDYQQIQDTHRHYKHKLEEVSKLQESCSSSIARQRKKLKDLSESLEECKGAVNPEDVNK 78

  Fly    74 VDDLHKMTLKRKAQLHEIEQSLPAKSGRYLQIILGDVNVSILNRNDKVRYKDDYEKFKLILNVIG 138
            :||:.:...:|.....|:|..||.|:|.||.::||:|||::||:..|..|||:||||||.|.|:.
Zfish    79 IDDIQESIKERPNVFFEMEAFLPKKNGLYLSLVLGNVNVTLLNKQSKFAYKDEYEKFKLYLTVLL 143

  Fly   139 LIMAF-FNLIFNYRALELAFIFLLVWYYCTLTIRESILKVNGSRIKGWWRAHHFISTVAAGVLLV 202
            |..:| ...:.:||.::..|.|||||||||||||||||..|||:|||||...|::||..:||:|.
Zfish   144 LFFSFTCRFLVSYRVVDALFNFLLVWYYCTLTIRESILINNGSKIKGWWVFQHYVSTFLSGVMLT 208

  Fly   203 WPQGEHWQIFRMQFMYFNVYISIVQYLQFGYQKGLLYRLKALGERHNMDITIEGFHSWMWRGLSF 267
            ||.||.:|:||.||:.:::||:.||:.|:.||.|.||||:|||||||||:|:|||.|||||||:|
Zfish   209 WPDGELYQMFRNQFLSYSMYINFVQFFQYYYQSGCLYRLRALGERHNMDLTVEGFQSWMWRGLTF 273

  Fly   268 LLPFLFIGYGYQAYNAWTLYKLAYSPPDAPWHVSVMSGLFLLLFVGNMATTLWVVPEKIRERAKE 332
            ||||||:|:.:|.||..||:::...|....|.|.:....||:||:||..|||.||..|..::.|.
Zfish   274 LLPFLFLGHFFQLYNGITLFQMTQLPEWKEWQVLMCGSTFLVLFMGNFFTTLGVVYHKYMDQDKA 338

  Fly   333 R 333
            :
Zfish   339 K 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32795	NP_001245509.1	TMPIT	7..329	CDD:285135	157/320 (49%)
tmem120aa	NP_001076452.1	TMPIT	12..335	CDD:285135	157/320 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595935
Domainoid	1	1.000	334	1.000	Domainoid score	I1105
eggNOG	1	0.900	-	-		E1_KOG4758
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12907
Inparanoid	1	1.050	336	1.000	Inparanoid score	I2369
OMA	1	1.010	-	-		QHG55657
OrthoDB	1	1.010	-	-		D398151at33208
OrthoFinder	1	1.000	-	-		FOG0002380
OrthoInspector	1	1.000	-	-		otm25225
orthoMCL	1	0.900	-	-		OOG6_103806
Panther	1	1.100	-	-	LDO	PTHR21433
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3603
SonicParanoid	1	1.000	-	-		X1574
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800