Protein Alignment Syx4 and Stx11

DIOPT Version :10

• Sequence 1: NP_525057.2
• Gene: Syx4 / 31269
• FlyBaseID: FBgn0024980
• Length: 333
• Species: Drosophila melanogaster
• Sequence 2: NP_083351.1
• Gene: Stx11 / 74732
• MGIID: 1921982
• Length: 287
• Species: Mus musculus
• Alignment Length: 277
• Identity: 60/277 - (21%)
• Similarity: 117/277 - (42%)
• Gaps: 48/277 - (17%)

  Fly    68 EPKDRSSSKMTQYGSNVDDILNPYTEIRQQLAQIAANLETMNRMAQTVNLRTFNENEM-----DE 127
            |.::.|.|...|:....:|...|..:|..:...|   ||::.|:.|.:.    :||::     ..
Mouse     7 ELQELSRSYDQQFPDGDNDFDAPREDIVFETDHI---LESLYRVIQDIQ----DENQLLLIDVRR 64

  Fly   128 LHNKNLR-----------------LGNQLMTRFNDFKANLPAENDYSLEARMKRTLFYGLHQTFI 175
            |..:|:|                 :...:.||.......|.:..:.|.:|..:    :|.|....
Mouse    65 LGRQNVRFLTSMRRLSSIKRDTNSIAKAIKTRGEGIHQKLRSMKELSEQAEAR----HGAHSAVA 125

  Fly   176 NLWH----------KNELFLQNY-ETKVKKNLRL----HTKIINSEASEQEIELLIENKTTKLFV 225
            .:.|          :..::..|. |.|.:.|.::    ..:|:..:.|.::||.:.|.....:|.
Mouse   126 RISHAQYSALARAFQQAMYEYNQAEMKQRDNCKIRIQRQLEIMGKDMSGEQIEDMFEQGKWDVFS 190

  Fly   226 DNFLQETEKERQTLREMMDRFNELRRLEKSIEEVHALFMRIQTLVMEQSEVIQRVEFHAQQATLH 290
            :|.|.:.:..|..|.|:..|..||.|||..|.:||.||:::..||.:|.:.:..:|.:.|:...:
Mouse   191 ENLLADLKGARAALNEIESRHRELLRLEGRIRDVHELFLQMAVLVEKQEDTLNVIELNVQKTLDY 255

  Fly   291 VDKGADELDQAEQHQKK 307
            ..:...::.:|.|::||
Mouse   256 TGEAKAQVRKAVQYKKK 272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syx4	NP_525057.2	COG5074	<187..313	CDD:227406	35/126 (28%)
		SNARE_syntaxin1-like	238..298	CDD:277201	18/59 (31%)
Stx11	NP_083351.1	Syntaxin	43..238	CDD:459942	43/202 (21%)
		SNARE	207..273	CDD:473982	20/66 (30%)