Protein Alignment Syx4 and Stx19

DIOPT Version :10

• Sequence 1: NP_525057.2
• Gene: Syx4 / 31269
• FlyBaseID: FBgn0024980
• Length: 333
• Species: Drosophila melanogaster
• Sequence 2: NP_080864.1
• Gene: Stx19 / 68159
• MGIID: 1915409
• Length: 292
• Species: Mus musculus
• Alignment Length: 316
• Identity: 61/316 - (19%)
• Similarity: 127/316 - (40%)
• Gaps: 53/316 - (16%)

  Fly     3 KDRLPELLQRSLSTNSSNSSSNGSLLLNVYSGTTEFIIGNTGGNNNSYSVVSQNSHSCSNNNSST 67
            ||||.||.|:   |.....|.:|.:.:....|...           ..:|:.:.
Mouse     2 KDRLQELKQK---TKEIELSRDGQVFVEEEQGVLV-----------QQAVIYER----------- 41

  Fly    68 EP-KDRSSSKMTQYGSNVDDILNPYTEIRQQLAQIAANLETMNRMAQTVNLRTFNENEMDELHNK 131
            || .:|...::.:...|::..::......||...:.|            ::|.|:..:.|....|
Mouse    42 EPVAERHLHEIQKLQENINSFVDDVQRFGQQQKSLVA------------SMRRFSLLKRDSTIAK 94

  Fly   132 NLRLGNQLMTR-----FNDFKANLPAENDYSLEARMKRTLFYGLHQTFINLWHKNELFLQN---- 187
            .:::..:.:.|     ..:.|.:.......|:..|:.::.:..:.:.|     :..:||.|
Mouse    95 EIKIQAEHINRALGDVVKEVKKSEVENGPSSVVTRILKSQYAAMFRRF-----QQTMFLYNDTIA 154

  Fly   188 -YETKVKKNLRLHTKIINSEASEQEIELLIENKTTKLFVDNFLQETEKERQTLREMMDRFNELRR 251
             .:.|.|..:....::...|.||:|:..::.:...::|.::.|.||...:..|.|:..|..||..
Mouse   155 LKQEKCKTFIVRQLEVAGKEVSEEEVNDMLHHGKWEVFNESLLTETSITKAQLSEIEQRHKELVN 219

  Fly   252 LEKSIEEVHALFMRIQTLVMEQSEVIQRVEFHAQQATLHVDKGADELDQAEQHQKK 307
            ||..::::..||::|..||.||.|.|..:|........:|:...::...|.:::|:
Mouse   220 LENQVKDLRDLFIQISLLVEEQGESINSIEVMVNSTKDYVNNTKEKFGLAVKYKKR 275

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syx4	NP_525057.2	COG5074	<187..313	CDD:227406	31/126 (25%)
		SNARE_syntaxin1-like	238..298	CDD:277201	18/59 (31%)
Stx19	NP_080864.1	Syntaxin	47..242	CDD:459942	40/211 (19%)
		SNARE	210..276	CDD:473982	18/66 (27%)