Protein Alignment Syx4 and STX4

DIOPT Version :9

• Sequence 1: NP_525057.2
• Gene: Syx4 / 31269
• FlyBaseID: FBgn0024980
• Length: 333
• Species: Drosophila melanogaster
• Sequence 2: NP_004595.2
• Gene: STX4 / 6810
• HGNCID: 11439
• Length: 297
• Species: Homo sapiens
• Alignment Length: 292
• Identity: 77/292 - (26%)
• Similarity: 154/292 - (52%)
• Gaps: 20/292 - (6%)

  Fly    57 SHSCSNNNSSTEPKDRSSSKM------TQYGSNVDDILNPYTEIRQQLAQIAANLETMNRMAQTV 115
            :|.....:.|::.:|:....:      .:.||..::..:....|||.:.::...::.:.:...|:
Human     5 THELRQGDDSSDEEDKERVALVVHPGTARLGSPDEEFFHKVRTIRQTIVKLGNKVQELEKQQVTI 69

  Fly   116 NLRTFNE----NEMDELHNKNLRLGNQLMTRFNDFKANLPA-----ENDYSLEARMKRTLFYGLH 171
            ......|    .|:..|.::..:||.::..:   .||..|.     ||..|:..||::|....|.
Human    70 LATPLPEESMKQELQNLRDEIKQLGREIRLQ---LKAIEPQKEEADENYNSVNTRMRKTQHGVLS 131

  Fly   172 QTFINLWHKNELFLQNYETKVKKNLRLHTKIINS-EASEQEIELLIENKTTKLFVDNFLQETEKE 235
            |.|:.|.:|.......|..|..:.:|...||.|: ..|::|:|.::::..:::||.|.|::|:..
Human   132 QQFVELINKCNSMQSEYREKNVERIRRQLKITNAGMVSDEELEQMLDSGQSEVFVSNILKDTQVT 196

  Fly   236 RQTLREMMDRFNELRRLEKSIEEVHALFMRIQTLVMEQSEVIQRVEFHAQQATLHVDKGADELDQ 300
            ||.|.|:..|.:|:::||:||.|:|.:|..:.|.|..|.|:|.|:|.:...:..:|::|.:.:..
Human   197 RQALNEISARHSEIQQLERSIRELHDIFTFLATEVEMQGEMINRIEKNILSSADYVERGQEHVKT 261

  Fly   301 AEQHQKKARKKKIML-IVILAAVLLVLLLVGI 331
            |.::||||||||::: |.:...|:|:.:::|:
Human   262 ALENQKKARKKKVLIAICVSITVVLLAVIIGV 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syx4	NP_525057.2	Syntaxin	93..273	CDD:279182	52/189 (28%)
		SNARE_syntaxin1-like	238..298	CDD:277201	20/59 (34%)
STX4	NP_004595.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21		3/15 (20%)
		SynN	39..189	CDD:238105	34/152 (22%)
		Interaction with CENPF. /evidence=ECO:0000250	154..297		47/140 (34%)
		SNARE_syntaxin4	199..261	CDD:277236	20/61 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5074
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53912
OrthoDB	1	1.010	-	-		D1033833at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19957
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.930