Protein Alignment Syx4 and STX2

DIOPT Version :9

• Sequence 1: NP_525057.2
• Gene: Syx4 / 31269
• FlyBaseID: FBgn0024980
• Length: 333
• Species: Drosophila melanogaster
• Sequence 2: XP_016874467.1
• Gene: STX2 / 2054
• HGNCID: 3403
• Length: 320
• Species: Homo sapiens
• Alignment Length: 315
• Identity: 70/315 - (22%)
• Similarity: 157/315 - (49%)
• Gaps: 25/315 - (7%)

  Fly    30 NVYSGTTEFIIGNTGGNNNSYSVVSQNSHSCSNNNSSTEPKDRSSSKMTQYGSNVDDILNPYTEI 94
            :.:||....:|.......:::.:: |::..|..|:      |..:..:.:....:||..:...||
Human    14 SAFSGQMHTVICALKPQYSAWCLI-QSTCQCRKND------DGDTVVVVEKDHFMDDFFHQVEEI 71

  Fly    95 RQQLAQIAANLETMNRMAQTVNLRTFN-----ENEMDELHNKNLRLGNQLMTRFNDFKANLPAE- 153
            |..:.:|...:|.:.: ..::.|...|     :.|:::|:.:..:..|::..:....:.:...:
Human    72 RNSIDKITQYVEEVKK-NHSIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDE 135

  Fly   154 --NDYSLEARMKRTLFYGLHQTFIN-LWHKNE---LFLQNYETKVKKNLRLHTKIINSEASEQEI 212
              |..|::.|::||....|.:.|:. :...||   ||.:..:.::::.|    :|.....::.|:
Human   136 SGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQL----EITGRTTTDDEL 196

  Fly   213 ELLIENKTTKLFVDNFLQETEKERQTLREMMDRFNELRRLEKSIEEVHALFMRIQTLVMEQSEVI 277
            |.::|:....:|..:.:.:::..||.|.|:..|..::.:||.||.|:|.:||.:...|..|.|:|
Human   197 EEMLESGKPSIFTSDIISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMI 261

  Fly   278 QRVEFHAQQATLHVDKGADELDQAEQHQKKARKKK-IMLIVILAAVLLVLLLVGI 331
            ..:|.:...||.:|:...:|..:|.::|.|||:|| |::.|.:..|.::.|::|:
Human   262 NNIERNVMNATDYVEHAKEETKKAIKYQSKARRKKWIIIAVSVVLVAIIALIIGL 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syx4	NP_525057.2	Syntaxin	93..273	CDD:279182	41/191 (21%)
		SNARE_syntaxin1-like	238..298	CDD:277201	19/59 (32%)
STX2	XP_016874467.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5074
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53912
OrthoDB	1	1.010	-	-		D1033833at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.830