DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG2712 and ZNF80

DIOPT Version :9

Sequence 1:NP_570028.1 Gene:CG2712 / 31267 FlyBaseID:FBgn0024975 Length:501 Species:Drosophila melanogaster
Sequence 2:NP_009067.2 Gene:ZNF80 / 7634 HGNCID:13155 Length:273 Species:Homo sapiens


Alignment Length:241 Identity:81/241 - (33%)
Similarity:123/241 - (51%) Gaps:12/241 - (4%)


- Green bases have known domain annotations that are detailed below.


  Fly   246 QAKAGEDVYEIVEKSAQTSATQKTLPSGSRPWKPLNPSLQCKICGKQLSTNNSFKYHMQLHGTAT 310
            |...|::::|...:    ..::.||....:.:|       ||.||...:.|:....|.|:|....
Human    22 QVSTGDNLHECDSQ----GPSKDTLVREGKTYK-------CKECGSVFNKNSLLVRHQQIHTGVK 75

  Fly   311 PYVCTICGESFKTRNARDGHVTLHDRNNPNRCPTCFKVYRQASSLRTHLLIHSGIKPFECSICGK 375
            ||.|..||::|..:......:.:|....|.:|..|.||:.:.|.|..:..||:|.||:|||.|||
Human    76 PYECQECGKAFPEKVDFVRPMRIHTGEKPCKCVECGKVFNRRSHLLCYRQIHTGEKPYECSECGK 140

  Fly   376 RLTQKSGYKKHMLTHTGEKPHGCDICGRRFRYSSNLIAHKRCHSQEKPHPCPVCQKRSFGSTSEL 440
            ..:..|.:.:|.:||||||..||..||:.|.|:|:|..|.:.|:.|||..|..|.| :|...|..
Human   141 TFSYHSVFIQHRVTHTGEKLFGCKECGKTFYYNSSLTRHMKIHTGEKPCKCSECGK-TFTYRSVF 204

  Fly   441 NRHMLVHSSERPFGCEQCGKSFKRRISLAIHRQSHKAGRQRRRAEH 486
            .||.:.|::.:|:.|::|||.|....||..|.:||...:.....||
Human   205 FRHSMTHTAGKPYECKECGKGFYYSYSLTRHTRSHTGEKPYECLEH 250

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG2712NP_570028.1 zf-AD 13..92 CDD:214871
C2H2 Zn finger 286..306 CDD:275368 7/19 (37%)
C2H2 Zn finger 314..334 CDD:275368 4/19 (21%)
C2H2 Zn finger 342..362 CDD:275368 6/19 (32%)
zf-H2C2_2 354..379 CDD:290200 12/24 (50%)
C2H2 Zn finger 370..390 CDD:275368 7/19 (37%)
COG5048 378..>463 CDD:227381 34/84 (40%)
zf-H2C2_2 384..407 CDD:290200 12/22 (55%)
C2H2 Zn finger 398..418 CDD:275368 8/19 (42%)
C2H2 Zn finger 426..447 CDD:275368 7/20 (35%)
zf-H2C2_2 439..464 CDD:290200 9/24 (38%)
C2H2 Zn finger 455..475 CDD:275368 8/19 (42%)
ZNF80NP_009067.2 COG5048 <51..227 CDD:227381 67/176 (38%)
C2H2 Zn finger 51..71 CDD:275368 7/19 (37%)
zf-H2C2_2 64..86 CDD:290200 8/21 (38%)
C2H2 Zn finger 79..99 CDD:275368 4/19 (21%)
C2H2 Zn finger 107..127 CDD:275368 6/19 (32%)
C2H2 Zn finger 135..155 CDD:275368 7/19 (37%)
C2H2 Zn finger 163..183 CDD:275368 8/19 (42%)
zf-H2C2_2 175..200 CDD:290200 10/25 (40%)
C2H2 Zn finger 191..211 CDD:275368 7/20 (35%)
C2H2 Zn finger 219..239 CDD:275368 8/19 (42%)
C2H2 Zn finger 247..267 CDD:275368 2/4 (50%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165146739
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.930

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