DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2712 and Zfp329

DIOPT Version :9

Sequence 1:	NP_570028.1	Gene:	CG2712 / 31267	FlyBaseID:	FBgn0024975	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	XP_006540378.1	Gene:	Zfp329 / 67230	MGIID:	1921283	Length:	553	Species:	Mus musculus

Alignment Length:	289	Identity:	95/289 - (32%)
Similarity:	135/289 - (46%)	Gaps:	30/289 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   191 RLERSEPALQCPICGKQLARKRTFQYHMRLHGQPKIRQEDNDHCIEECLQVEPVLQAKAGEDVYE 255
            |...:|...:|..|||...|..:...|.|.|...|      .:...:|        .|:....|.
Mouse   207 RSHSAEKPYKCAECGKCFKRNSSLVLHHRTHTGEK------PYTCNDC--------GKSFSKNYN 257

  Fly   256 IVEKSAQTSATQKTLPSGSRPWKPLNPSLQCKICGKQLSTNNSFKYHMQLHGTATPYVCTICGES 320
            ::        ..:.:.:|.:|:|       |..|||..|..::...|.::|....||.|..||::
Mouse   258 LI--------VHRRIHTGEKPYK-------CSKCGKAFSDGSALTQHQRIHTGEKPYACLDCGKT 307

  Fly   321 FKTRNARDGHVTLHDRNNPNRCPTCFKVYRQASSLRTHLLIHSGIKPFECSICGKRLTQKSGYKK 385
            |...::...|...|....|.||..|.|.:...|.|..||.||:|.||:|||.|||.....|...:
Mouse   308 FNRNSSLILHQRTHTGEKPYRCNECGKPFTDISHLTVHLRIHTGEKPYECSRCGKAFRDGSYLTQ 372

  Fly   386 HMLTHTGEKPHGCDICGRRFRYSSNLIAHKRCHSQEKPHPCPVCQKRSFGSTSELNRHMLVHSSE 450
            |..|||||||..|..||:.|..:|:||.|::.||.|||:.|..|.| :|..::.|.||..||:.|
Mouse   373 HERTHTGEKPFECVECGKSFSRNSHLIVHQKIHSGEKPYECKECGK-TFIESAYLIRHQRVHTGE 436

  Fly   451 RPFGCEQCGKSFKRRISLAIHRQSHKAGR 479
            :|:||.||.|.|:....|..|::.|...|
Mouse   437 KPYGCNQCRKLFRNIAGLIRHQRIHTGER 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2712	NP_570028.1	zf-AD	13..92	CDD:214871
		C2H2 Zn finger	286..306	CDD:275368	6/19 (32%)
		C2H2 Zn finger	314..334	CDD:275368	5/19 (26%)
		C2H2 Zn finger	342..362	CDD:275368	7/19 (37%)
		zf-H2C2_2	354..379	CDD:290200	14/24 (58%)
		C2H2 Zn finger	370..390	CDD:275368	7/19 (37%)
		COG5048	378..>463	CDD:227381	38/84 (45%)
		zf-H2C2_2	384..407	CDD:290200	12/22 (55%)
		C2H2 Zn finger	398..418	CDD:275368	8/19 (42%)
		C2H2 Zn finger	426..447	CDD:275368	7/20 (35%)
		zf-H2C2_2	439..464	CDD:290200	13/24 (54%)
		C2H2 Zn finger	455..475	CDD:275368	7/19 (37%)
Zfp329	XP_006540378.1	COG5048	<85..336	CDD:227381	37/157 (24%)
		C2H2 Zn finger	217..237	CDD:275368	7/19 (37%)
		COG5048	<226..481	CDD:227381	89/270 (33%)
		C2H2 Zn finger	245..265	CDD:275368	3/35 (9%)
		C2H2 Zn finger	273..293	CDD:275368	6/19 (32%)
		C2H2 Zn finger	301..321	CDD:275368	5/19 (26%)
		C2H2 Zn finger	329..349	CDD:275368	7/19 (37%)
		C2H2 Zn finger	357..377	CDD:275368	7/19 (37%)
		C2H2 Zn finger	385..405	CDD:275368	8/19 (42%)
		C2H2 Zn finger	413..433	CDD:275368	7/20 (35%)
		C2H2 Zn finger	441..461	CDD:275368	7/19 (37%)
		C2H2 Zn finger	469..489	CDD:275368
		zf-H2C2_2	482..506	CDD:372612
		C2H2 Zn finger	497..517	CDD:275368
		C2H2 Zn finger	525..545	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836673
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24381
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030