DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2712 and Zfp971

DIOPT Version :9

Sequence 1:	NP_570028.1	Gene:	CG2712 / 31267	FlyBaseID:	FBgn0024975	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_001170870.1	Gene:	Zfp971 / 626848	MGIID:	1261426	Length:	470	Species:	Mus musculus

Alignment Length:	347	Identity:	109/347 - (31%)
Similarity:	150/347 - (43%)	Gaps:	59/347 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   187 QRRSRLERSEPALQCPICGKQLARKRTFQYHMRLHGQPK----------------IRQEDNDHCI 235
            ||..|....|...:|..|||......|.|.|.|.|...|                :|.....|..
Mouse   119 QRLKRTHTGEKPYECNHCGKAFVESCTLQIHKRKHTGEKPYECNQCGKAFAQSCHLRIHKRTHTG 183

  Fly   236 E---ECLQVEPVL----------QAKAGEDVYEIVE--KSAQTSA---TQKTLPSGSRPWKPLNP 282
            |   ||.|.....          :...||..||..:  |:...|:   ..|...:|.:|:
Mouse   184 EKPYECKQCGKAFAVSSHLGIHKRTHTGEKPYECKQCGKAFAVSSHLGIHKRTHTGEKPY----- 243

  Fly   283 SLQCKICGKQLSTNNSFKYHMQLHGTATPYVCTICGESFKTRNARDGHVTLHDRNN----PNRCP 343
              :||.|.|........:.|.:.|....||.|..||::|    |..|.:.:|.|.:    |..|.
Mouse   244 --ECKQCDKAFVRRGKLQIHKRTHTGEKPYECKQCGKAF----AHSGTLQIHKRTHTGEKPYECY 302

  Fly   344 TCFKVYRQASSLRTHLLIHSGIKPFECSICGKRLTQKSGYKKHMLTHTGEKPHGCDICGRRFRYS 408
            .|.|.:..:..||.|...|||.|.:||:.|||.....|..:||..||||:||:.|..||:.|..|
Mouse   303 QCGKAFATSCHLRRHNRTHSGEKQYECNQCGKAFASSSDLQKHKRTHTGDKPYECKQCGKAFASS 367

  Fly   409 SNLIAHKRCHSQEKPHPCPVCQKRSFGSTSELNRHMLVHSSERPFGCEQCGKSFKRRISLAIHRQ 473
            |:|..|||.|:.|||:.|..|.| :|..:|.|.||...|:.|:|:.|:||||:|.|...|.||::
Mouse   368 SDLQKHKRTHTGEKPYECKQCGK-AFAESSTLQRHKRTHTGEKPYECKQCGKAFARSCHLQIHKR 431

  Fly   474 SH---------KAGRQRRRAEH 486
            :|         :.|:...|:.|
Mouse   432 THTGEKPYECKQCGKAFARSSH 453

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2712	NP_570028.1	zf-AD	13..92	CDD:214871
		C2H2 Zn finger	286..306	CDD:275368	5/19 (26%)
		C2H2 Zn finger	314..334	CDD:275368	6/19 (32%)
		C2H2 Zn finger	342..362	CDD:275368	6/19 (32%)
		zf-H2C2_2	354..379	CDD:290200	12/24 (50%)
		C2H2 Zn finger	370..390	CDD:275368	7/19 (37%)
		COG5048	378..>463	CDD:227381	39/84 (46%)
		zf-H2C2_2	384..407	CDD:290200	12/22 (55%)
		C2H2 Zn finger	398..418	CDD:275368	10/19 (53%)
		C2H2 Zn finger	426..447	CDD:275368	8/20 (40%)
		zf-H2C2_2	439..464	CDD:290200	12/24 (50%)
		C2H2 Zn finger	455..475	CDD:275368	10/19 (53%)
Zfp971	NP_001170870.1	KRAB	4..>45	CDD:214630
		KRAB	4..43	CDD:279668
		COG5048	75..458	CDD:227381	109/347 (31%)
		C2H2 Zn finger	79..97	CDD:275368
		C2H2 Zn finger	105..125	CDD:275368	3/5 (60%)
		C2H2 Zn finger	133..153	CDD:275368	8/19 (42%)
		zf-H2C2_2	146..170	CDD:290200	5/23 (22%)
		C2H2 Zn finger	161..181	CDD:275368	1/19 (5%)
		zf-H2C2_2	173..197	CDD:290200	6/23 (26%)
		C2H2 Zn finger	189..209	CDD:275368	2/19 (11%)
		zf-H2C2_2	201..225	CDD:290200	5/23 (22%)
		C2H2 Zn finger	217..237	CDD:275368	3/19 (16%)
		zf-H2C2_2	229..254	CDD:290200	7/31 (23%)
		C2H2 Zn finger	245..265	CDD:275368	5/19 (26%)
		zf-H2C2_2	258..282	CDD:290200	8/27 (30%)
		C2H2 Zn finger	273..293	CDD:275368	8/23 (35%)
		zf-H2C2_2	286..310	CDD:290200	6/23 (26%)
		C2H2 Zn finger	301..321	CDD:275368	6/19 (32%)
		zf-H2C2_2	313..338	CDD:290200	12/24 (50%)
		C2H2 Zn finger	329..349	CDD:275368	7/19 (37%)
		zf-H2C2_2	341..366	CDD:290200	12/24 (50%)
		C2H2 Zn finger	357..377	CDD:275368	10/19 (53%)
		zf-H2C2_2	369..393	CDD:290200	11/24 (46%)
		C2H2 Zn finger	385..405	CDD:275368	8/20 (40%)
		zf-H2C2_2	398..422	CDD:290200	12/23 (52%)
		C2H2 Zn finger	413..433	CDD:275368	10/19 (53%)
		zf-H2C2_2	425..450	CDD:290200	5/24 (21%)
		C2H2 Zn finger	441..461	CDD:275368	3/13 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24381
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100