DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG2712 and Zfp248

DIOPT Version :9

Sequence 1:NP_570028.1 Gene:CG2712 / 31267 FlyBaseID:FBgn0024975 Length:501 Species:Drosophila melanogaster
Sequence 2:XP_038964719.1 Gene:Zfp248 / 500304 RGDID:1561270 Length:576 Species:Rattus norvegicus


Alignment Length:358 Identity:110/358 - (30%)
Similarity:163/358 - (45%) Gaps:43/358 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly   135 ETIRDEEQL--LVVESDEAESRLEAPIVQEERLDIALEQHEDDLCE---IVDDPDPEQR----RS 190
            ||:|...:.  ..|:|      |:..:.|:..|.  .|.||..:|.   .||.....||    .|
  Rat   236 ETLRKHTECGRTFVDS------LKLSVSQKTHLH--AEPHECSICRKSFYVDLQFGHQRAISGNS 292

  Fly   191 RLERSE-PALQCP-----ICGKQLARKRTFQYHM--RLHGQPKIRQEDNDHCIEECLQVEPVLQA 247
            ..|||| ..|.|.     :..:...||.:.:|.:  |..|:|.:.:       .:.:|:      
  Rat   293 PYERSEYEKLFCDHSAFIVHQEAYTRKISQEYKVSNRTWGKPALFK-------HQIIQI------ 344

  Fly   248 KAGEDVYEIVEKSAQTSATQKTLPSGSRPWKPLNPSLQCKICGKQLSTNNSFKYHMQLHGTATPY 312
              |...||..|.  :.:.::|:.|:.||.......:.:|..|||.....::...|.:.|....||
  Rat   345 --GGKPYEYHEN--RKNFSKKSHPTQSRRAHVGEKTFECGECGKMFWEKSNLTQHQRTHTGEKPY 405

  Fly   313 VCTICGESFKTRNARDGHVTLHDRNNPNRCPTCFKVYRQASSLRTHLLIHSGIKPFECSICGKRL 377
            .||.||::|..:.....|...|....|..|..|.|.:...|:|..|...|:|.||:||:.|.|..
  Rat   406 ACTECGKAFCQKPHLTNHQRTHTGEKPYECKQCGKTFCVKSNLTEHQRTHTGEKPYECNACRKSF 470

  Fly   378 TQKSGYKKHMLTHTGEKPHGCDICGRRFRYSSNLIAHKRCHSQEKPHPCPVCQKRSFGSTSELNR 442
            ..:|....|..|||||||..|:.||:.|...||||.|:|.|:.|||:.|..|:| :|...|.|.:
  Rat   471 CHRSALTVHQRTHTGEKPFICNECGKSFCVKSNLIVHQRTHTGEKPYKCNECEK-TFCEKSALTK 534

  Fly   443 HMLVHSSERPFGCEQCGKSFKRRISLAIHRQSH 475
            |...|:.|:|:.|..|||:|.:|..|..|::.|
  Rat   535 HQRTHTGEKPYECNVCGKTFSQRSVLTKHQRIH 567

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG2712NP_570028.1 zf-AD 13..92 CDD:214871
C2H2 Zn finger 286..306 CDD:275368 5/19 (26%)
C2H2 Zn finger 314..334 CDD:275368 6/19 (32%)
C2H2 Zn finger 342..362 CDD:275368 6/19 (32%)
zf-H2C2_2 354..379 CDD:290200 10/24 (42%)
C2H2 Zn finger 370..390 CDD:275368 5/19 (26%)
COG5048 378..>463 CDD:227381 37/84 (44%)
zf-H2C2_2 384..407 CDD:290200 12/22 (55%)
C2H2 Zn finger 398..418 CDD:275368 10/19 (53%)
C2H2 Zn finger 426..447 CDD:275368 7/20 (35%)
zf-H2C2_2 439..464 CDD:290200 10/24 (42%)
C2H2 Zn finger 455..475 CDD:275368 8/19 (42%)
Zfp248XP_038964719.1 KRAB 8..68 CDD:214630
C2H2 Zn finger 242..261 CDD:275370 4/24 (17%)
C2H2 Zn finger 379..399 CDD:275368 5/19 (26%)
COG5048 403..>469 CDD:227381 23/65 (35%)
C2H2 Zn finger 407..427 CDD:275368 6/19 (32%)
C2H2 Zn finger 435..455 CDD:275368 6/19 (32%)
C2H2 Zn finger 463..483 CDD:275368 5/19 (26%)
zf-H2C2_2 475..498 CDD:404364 11/22 (50%)
zf-C2H2 489..511 CDD:395048 10/21 (48%)
C2H2 Zn finger 491..511 CDD:275368 10/19 (53%)
COG5048 515..>568 CDD:227381 21/54 (39%)
C2H2 Zn finger 519..539 CDD:275368 7/20 (35%)
zf-H2C2_2 531..556 CDD:404364 10/24 (42%)
C2H2 Zn finger 547..567 CDD:275368 8/19 (42%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24381
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

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