DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG2712 and ZNF705A

DIOPT Version :9

Sequence 1:NP_570028.1 Gene:CG2712 / 31267 FlyBaseID:FBgn0024975 Length:501 Species:Drosophila melanogaster
Sequence 2:XP_024304748.1 Gene:ZNF705A / 440077 HGNCID:32281 Length:315 Species:Homo sapiens


Alignment Length:260 Identity:75/260 - (28%)
Similarity:120/260 - (46%) Gaps:30/260 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly   205 GKQLARKRTFQYHMRLHGQPKIRQEDNDHCIEECLQVEPVLQAKAGEDVYEIVEKSAQTSATQKT 269
            ||:|.|:          |:..::.::.|.        |..|:.|....::.|..|.|.||.|.:.
Human    77 GKELWRE----------GREFLQDQNPDR--------ESALKKKHMISMHPITRKDASTSMTMEN 123

  Fly   270 LPSGSRPWKPLNPSLQCKICGKQLSTNNSFKYHMQLHGTATPYVCTICGESFKTRNARDGHVTLH 334
            .       ..|....:|...|:..:.:::....:..|....|||...||:|.:...:...|..:|
Human   124 S-------LILEDPFECNDSGEDCTHSSTITQRLLTHSGKKPYVSKQCGKSLRNLFSPKPHKQIH 181

  Fly   335 DRNNPNRCPTCFKVYRQASSLRTHLLIHSGIKPFECSICGKRLTQKSGYKKHMLTHTGEKPHGCD 399
            .:....:|..|.|.|.....||.|.:.|:|.:|:.|.:|||..||.|..::|..|||||:|:.|.
Human   182 TKGKSYQCNLCEKAYTNCFRLRRHKMTHTGERPYACHLCGKAFTQCSHLRRHEKTHTGERPYKCH 246

  Fly   400 ICGRRFRYSSNLIAHKRCHSQEKPHPCPVCQK--RSFGSTSELNRHMLVHSSERPFGCEQCGKSF 462
            .||:.|..|.||..|:|.|..:|   |..|.|  ::|..:|....:.::|:.|:|..|..|||:|
Human   247 QCGKAFIQSFNLRRHERTHLGKK---CYECDKSGKAFSQSSGFRGNKIIHTGEKPHACLLCGKAF 308

  Fly   463  462
            Human   309  308

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG2712NP_570028.1 zf-AD 13..92 CDD:214871
C2H2 Zn finger 286..306 CDD:275368 2/19 (11%)
C2H2 Zn finger 314..334 CDD:275368 4/19 (21%)
C2H2 Zn finger 342..362 CDD:275368 7/19 (37%)
zf-H2C2_2 354..379 CDD:290200 10/24 (42%)
C2H2 Zn finger 370..390 CDD:275368 8/19 (42%)
COG5048 378..>463 CDD:227381 34/87 (39%)
zf-H2C2_2 384..407 CDD:290200 11/22 (50%)
C2H2 Zn finger 398..418 CDD:275368 9/19 (47%)
C2H2 Zn finger 426..447 CDD:275368 5/22 (23%)
zf-H2C2_2 439..464 CDD:290200 8/24 (33%)
C2H2 Zn finger 455..475 CDD:275368 5/8 (63%)
ZNF705AXP_024304748.1 KRAB 22..81 CDD:214630 2/3 (67%)
C2H2 Zn finger 133..153 CDD:275368 2/19 (11%)
COG5048 <136..315 CDD:227381 58/176 (33%)
C2H2 Zn finger 162..181 CDD:275368 4/18 (22%)
C2H2 Zn finger 189..209 CDD:275368 7/19 (37%)
zf-H2C2_2 201..226 CDD:316026 10/24 (42%)
C2H2 Zn finger 217..237 CDD:275368 8/19 (42%)
zf-H2C2_2 229..254 CDD:316026 11/24 (46%)
C2H2 Zn finger 245..265 CDD:275368 9/19 (47%)
C2H2 Zn finger 273..293 CDD:275368 4/19 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165146595
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24381
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
22.030

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