DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG2712 and Zfp69

DIOPT Version :9

Sequence 1:NP_570028.1 Gene:CG2712 / 31267 FlyBaseID:FBgn0024975 Length:501 Species:Drosophila melanogaster
Sequence 2:NP_001005788.2 Gene:Zfp69 / 381549 MGIID:107794 Length:587 Species:Mus musculus


Alignment Length:488 Identity:115/488 - (23%)
Similarity:178/488 - (36%) Gaps:163/488 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly    68 DCVAKLRLSLEFKRSVHRMDRILRQSHADFCRSKKISAVNTRARLSTEIPEDFVLVLDDQEVTEY 132
            |.:..::..||.|.|....|..::..|.           .||.||.    ||.::....::.:.|
Mouse   200 DPILDVKNKLETKESTAEDDISVKLDHG-----------ITRGRLI----EDDIVCSPLKKASSY 249

  Fly   133 PAETIRDEEQLLVVESDEAE-------------------SRLEAPIVQEERLDIALEQ----HED 174
             ::|:         ||..|.                   ::||.|    |..::.|||    |: 
Mouse   250 -SDTL---------ESHRATCGKGTRRAIWTHKKKRQEGNKLENP----ESSNVILEQKHRKHK- 299

  Fly   175 DLCEIVDDPDPEQRRSRLE-------------RSEPALQCPICGKQLARKRTFQYHMRLHGQPKI 226
                      |.::|::.:             |..|   |.:|.|...:......|||.|     
Mouse   300 ----------PARKRNKYKLDSIDHPVSCMRARRYP---CNVCEKMFKQPIHLVEHMRTH----- 346

  Fly   227 RQEDNDHCIEECLQVEPVLQAKAGEDVYEIVEKSAQTSATQKTLPSGSRPWKPLNPSLQCKICGK 291
                                                         :|.:|::       ||.||:
Mouse   347 ---------------------------------------------TGEKPFR-------CKECGR 359

  Fly   292 QLSTNNSFKYHMQLHGTATPYVCTICGESFKTRNARDGHVTLHDRNNPNRCPTCFKVYRQASSLR 356
            ..|.:.|...|.::|....|:.|..||::|:.|::.:.|...|....|..|..|.|.:.|..||.
Mouse   360 AFSQSASLNTHQRIHTGEKPFACEECGKAFRHRSSLNQHHRTHTGEKPFTCDKCQKAFSQNISLV 424

  Fly   357 THLLIHSGIKPFECSICGKRLTQKSGYKKHMLTHTGEKPHGCDICGRRFRYSSNLIAHKRCHSQE 421
            .||..|||.|||.||.|||...|.....:|:..||||||:.|..|.:.|.:.:.|..|:|.|:.|
Mouse   425 QHLRTHSGEKPFSCSECGKPFRQIRHLSEHVRIHTGEKPYKCTSCCKTFSHRAYLTHHQRIHTGE 489

  Fly   422 KPHPCPVCQK---------------------------RSFGSTSELNRHMLVHSSERPFGCEQCG 459
            :|:.|..|.|                           :::...|...:|...|:.|:|:.|.:||
Mouse   490 RPYKCKECGKAFRQRIHLSNHRTVHTGVKAYECNRCGKAYRHDSSFKKHQRHHTGEKPYECTECG 554

  Fly   460 KSFKRRISLAIHRQSHKAGRQRRRAEHEVGVQL 492
            |||....||:.|::.|:....|....||...||
Mouse   555 KSFSYNSSLSRHQKIHRRNTFRDDPGHENKRQL 587

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG2712NP_570028.1 zf-AD 13..92 CDD:214871 6/23 (26%)
C2H2 Zn finger 286..306 CDD:275368 7/19 (37%)
C2H2 Zn finger 314..334 CDD:275368 6/19 (32%)
C2H2 Zn finger 342..362 CDD:275368 8/19 (42%)
zf-H2C2_2 354..379 CDD:290200 15/24 (63%)
C2H2 Zn finger 370..390 CDD:275368 7/19 (37%)
COG5048 378..>463 CDD:227381 30/111 (27%)
zf-H2C2_2 384..407 CDD:290200 10/22 (45%)
C2H2 Zn finger 398..418 CDD:275368 6/19 (32%)
C2H2 Zn finger 426..447 CDD:275368 5/47 (11%)
zf-H2C2_2 439..464 CDD:290200 10/24 (42%)
C2H2 Zn finger 455..475 CDD:275368 9/19 (47%)
Zfp69NP_001005788.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 42..128
CTD 52..>128 CDD:215026
KRAB 131..192 CDD:214630
COG5048 <279..510 CDD:227381 77/305 (25%)
C2H2 Zn finger 326..346 CDD:275368 6/19 (32%)
C2H2 Zn finger 354..374 CDD:275368 7/19 (37%)
C2H2 Zn finger 382..402 CDD:275368 6/19 (32%)
C2H2 Zn finger 410..430 CDD:275368 8/19 (42%)
C2H2 Zn finger 438..458 CDD:275368 7/19 (37%)
C2H2 Zn finger 466..486 CDD:275368 6/19 (32%)
C2H2 Zn finger 494..542 CDD:275368 5/47 (11%)
zf-H2C2_2 534..559 CDD:316026 10/24 (42%)
C2H2 Zn finger 550..570 CDD:275368 9/19 (47%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 564..587 5/22 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167836688
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.930

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