DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG2712 and Zfp157

DIOPT Version :9

Sequence 1:NP_570028.1 Gene:CG2712 / 31267 FlyBaseID:FBgn0024975 Length:501 Species:Drosophila melanogaster
Sequence 2:XP_038945496.1 Gene:Zfp157 / 360775 RGDID:1359435 Length:569 Species:Rattus norvegicus


Alignment Length:509 Identity:131/509 - (25%)
Similarity:194/509 - (38%) Gaps:117/509 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    22 PRCLPLFKPLDDPISGKPAT----LASILSYCSGLEILEAELFLPHHI--------CPDCVAKLR 74
            |..|.::.| |:.....|.:    :.||....|..|::|||:.:...:        |..|:..:.
  Rat    76 PGVLEVYTP-DESCLENPESHMWPVGSISRNLSNKEMIEAEMKVQLELYRGTKPCECKPCMKMVS 139

  Fly    75 LSLEFKRSVHRMDRILRQSHADFCRSKKISAVNTRARLSTEIPEDFVLVLDDQEVTEYPAETIRD 139
            |.|:           ..:.||.:.|.|.                                     
  Rat   140 LPLQ-----------RNEQHAYYARVKP------------------------------------- 156

  Fly   140 EEQLLVVESDEAESRL--EAPIVQEERLDIALEQHEDDLCEIVDDPDPEQR-RSRLERSEPALQC 201
                  .|..|.:...  ::.:.|.:|....|:.::...|........|.. ..|:...|...:|
  Rat   157 ------YEWKECQKAFCYKSALTQHQRPRTRLKIYQCTECRKAFPSKSELTVHHRIHTGEKPHEC 215

  Fly   202 PICGKQLARKRTFQYHMRLHGQPKIRQEDNDHCIEECLQVEPVLQAKAGEDVYEIVEKSAQTSAT 266
            ..|||...||.|...|.:.|     |.|....|.|.|         ||      ...||..|.  
  Rat   216 DECGKAFYRKSTLTVHQKTH-----RGEKPYECKECC---------KA------FYYKSTLTE-- 258

  Fly   267 QKTLPSGSRPWKPLNPSLQCKICGKQLSTNNSFKYHMQLHGTATPYVCTICGESFKTRNARDGHV 331
            .:.:.:|.:|:       .||.|||.....::...|.:.|....||.|..|.:.|.:::....|.
  Rat   259 HQRIHTGEKPY-------VCKECGKAFFYKSNLTRHHRTHTGEKPYECEECRKGFSSKSELTSHH 316

  Fly   332 TLHDRNNPNRCPTCFKVYRQASSLRTHLLIHSGIKPFECSICGKRLTQKSGYKKHMLTHTGEKPH 396
            ..|....|.:|..|.|.:...|:||.|..||:|.||:||..|.|....||...:|..|||||||:
  Rat   317 RTHTGEKPYQCEECGKAFYCKSTLRVHQKIHTGEKPYECKECQKSFYYKSTLTEHQRTHTGEKPY 381

  Fly   397 GCDICGRRFRYSSNLIAHKRCHSQEKPHPCPVCQKRSFGSTSELNRHMLVHSSERPFGCEQCGKS 461
            .|..||:.|.|.|.|..|.|.|:.|||:.|..|:| :|.|.|||..|...|:.|:|:.||:|||.
  Rat   382 ECKDCGKAFFYKSQLTRHHRIHTGEKPYECEECRK-AFSSKSELTAHHRTHTGEKPYECEECGKC 445

  Fly   462 FKRRISLAIHRQSH-----------------KAGRQRRRAEHEVGVQLEEQDEN 498
            |.|:..|.:|.:.|                 |:|..|....|..|...:.::::
  Rat   446 FCRKSHLTLHHRIHTGEKPYECKDCRKAFFCKSGLARHLGTHTHGTNTKNREKH 499

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG2712NP_570028.1 zf-AD 13..92 CDD:214871 16/81 (20%)
C2H2 Zn finger 286..306 CDD:275368 6/19 (32%)
C2H2 Zn finger 314..334 CDD:275368 4/19 (21%)
C2H2 Zn finger 342..362 CDD:275368 7/19 (37%)
zf-H2C2_2 354..379 CDD:290200 12/24 (50%)
C2H2 Zn finger 370..390 CDD:275368 6/19 (32%)
COG5048 378..>463 CDD:227381 40/84 (48%)
zf-H2C2_2 384..407 CDD:290200 12/22 (55%)
C2H2 Zn finger 398..418 CDD:275368 9/19 (47%)
C2H2 Zn finger 426..447 CDD:275368 9/20 (45%)
zf-H2C2_2 439..464 CDD:290200 12/24 (50%)
C2H2 Zn finger 455..475 CDD:275368 9/19 (47%)
Zfp157XP_038945496.1 KRAB 5..65 CDD:214630
C2H2 Zn finger 160..179 CDD:275368 3/18 (17%)
COG5048 183..529 CDD:227381 106/347 (31%)
C2H2 Zn finger 187..207 CDD:275368 3/19 (16%)
C2H2 Zn finger 215..235 CDD:275368 8/19 (42%)
C2H2 Zn finger 243..263 CDD:275368 8/36 (22%)
C2H2 Zn finger 271..291 CDD:275368 6/19 (32%)
C2H2 Zn finger 299..319 CDD:275368 4/19 (21%)
C2H2 Zn finger 327..347 CDD:275368 7/19 (37%)
C2H2 Zn finger 355..375 CDD:275368 6/19 (32%)
C2H2 Zn finger 383..403 CDD:275368 9/19 (47%)
C2H2 Zn finger 411..431 CDD:275368 9/20 (45%)
C2H2 Zn finger 439..459 CDD:275368 9/19 (47%)
C2H2 Zn finger 467..487 CDD:275368 3/19 (16%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24381
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

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