DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2712 and Zbtb41

DIOPT Version :9

Sequence 1:	NP_570028.1	Gene:	CG2712 / 31267	FlyBaseID:	FBgn0024975	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_001178599.1	Gene:	Zbtb41 / 289052	RGDID:	1560834	Length:	908	Species:	Rattus norvegicus

Alignment Length:	468	Identity:	126/468 - (26%)
Similarity:	198/468 - (42%)	Gaps:	69/468 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 FLPHHICPDCVAKLRLSLEFKRSVHRMDRILRQSHADFCRSKK-------ISAVNTRARLSTEIP 117
            |...|.|            :|:|   ::..|.::|......||       .|....|::.:.:.|
  Rat   212 FCSRHFC------------YKKS---LENHLAKTHRSLLLGKKHGLKMLERSFSTRRSKRNRKCP 261

  Fly   118 EDFVLVLDDQEVTEYPAETIRDEEQLLVVESDEAESRLEAP----IVQEERLDIALEQHEDDLCE 178
            ..|....||::.:...::.: ::|......||..:|  |.|    .|::|.|:..:...|.|..:
  Rat   262 VKFDDTSDDEQESGDGSDNL-NQESFDKERSDRNDS--EDPGSDYNVEDEELEEEVSDEESDTEQ 323

  Fly   179 IVDDPDPEQRRSRLE----------------RSEPALQCPICGKQLARKRTFQYHMRLHGQPKIR 227
            ...|.|.|:.....:                .::..||||.|.|...|...::.|.|:|...|..
  Rat   324 SDKDNDAEEEPEAADSAGSIHEGLAPVVIQNSNKKILQCPKCDKTFDRIGKYESHTRVHTGEKPF 388

  Fly   228 QEDNDHCIEECLQVEPVLQAKAGEDVYEIVEKS------AQTSATQKTLPSGSRPWKPLN----- 281
            :.|..|..........|.:.|...:| |..:|.      .:..|::|||....:.:.|.|
  Rat   389 ECDICHQRYSTKSNLTVHRKKHSSEV-EFHKKEHKCPYCNKLHASKKTLAKHVKRFHPENAQEFI 452

  Fly   282 -------PSLQCKICGKQLSTNNSFKYHMQLHGTATPYVCTICGESFKTRNARDGH-VTLHDRNN 338
                   .|.:|.||.|..:.....:.||.||....|:.||.|.|.||:|.||..| ...|  ..
  Rat   453 SIKKTKSESWKCDICKKSFTRRPHLEEHMILHSQDKPFKCTYCEEHFKSRFARLKHQEKFH--LG 515

  Fly   339 PNRCPTCFKVYRQASSLRTHL-LIHSGIKPFECSICGKRLTQKSGYKKHMLTHTGEKPHGCDICG 402
            |..|..|.:.:....:|:.|: ..|.|.:.:.|.||||.:.:::..|:|:..|:|||||.|.|||
  Rat   516 PFPCDICGRQFNDTGNLKRHIECTHGGKRKWTCFICGKSVRERTTLKEHLRIHSGEKPHLCSICG 580

  Fly   403 RRFRYSSNLIAHKRCHSQEKPHPCPVCQKRSFGSTSELNRHMLVHSSERPFGCEQCGKSFKRRIS 467
            :.||:.|:...|.|.|..:|.:.|..|.| :|.....|.:|..:||.|:...||:|||.|.||..
  Rat   581 QSFRHGSSYRLHLRVHHDDKRYECDECGK-TFIRHDHLTKHKKIHSGEKAHQCEECGKCFGRRDH 644

  Fly   468 LAIHRQSHKAGRQ 480
            |.:|.:|...|.:
  Rat   645 LTVHYKSVHLGEK 657

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2712	NP_570028.1	zf-AD	13..92	CDD:214871	6/31 (19%)
		C2H2 Zn finger	286..306	CDD:275368	6/19 (32%)
		C2H2 Zn finger	314..334	CDD:275368	10/20 (50%)
		C2H2 Zn finger	342..362	CDD:275368	4/20 (20%)
		zf-H2C2_2	354..379	CDD:290200	9/25 (36%)
		C2H2 Zn finger	370..390	CDD:275368	7/19 (37%)
		COG5048	378..>463	CDD:227381	33/84 (39%)
		zf-H2C2_2	384..407	CDD:290200	13/22 (59%)
		C2H2 Zn finger	398..418	CDD:275368	9/19 (47%)
		C2H2 Zn finger	426..447	CDD:275368	6/20 (30%)
		zf-H2C2_2	439..464	CDD:290200	11/24 (46%)
		C2H2 Zn finger	455..475	CDD:275368	10/19 (53%)
Zbtb41	NP_001178599.1	BTB	78..174	CDD:279045
		BTB	90..174	CDD:197585
		C2H2 Zn finger	362..382	CDD:275368	7/19 (37%)
		C2H2 Zn finger	390..410	CDD:275368	3/19 (16%)
		C2H2 Zn finger	423..441	CDD:275368	4/17 (24%)
		C2H2 Zn finger	464..484	CDD:275368	6/19 (32%)
		C2H2 Zn finger	492..509	CDD:275368	9/16 (56%)
		C2H2 Zn finger	519..540	CDD:275368	4/20 (20%)
		C2H2 Zn finger	548..568	CDD:275368	7/19 (37%)
		zf-H2C2_2	561..585	CDD:290200	13/23 (57%)
		C2H2 Zn finger	576..596	CDD:275368	9/19 (47%)
		zf-C2H2	602..624	CDD:278523	6/22 (27%)
		C2H2 Zn finger	604..624	CDD:275368	6/20 (30%)
		zf-H2C2_2	616..641	CDD:290200	11/24 (46%)
		C2H2 Zn finger	632..650	CDD:275368	10/17 (59%)
		C2H2 Zn finger	669..686	CDD:275368
		zf-H2C2_2	681..704	CDD:290200
		C2H2 Zn finger	697..717	CDD:275368
		C2H2 Zn finger	725..742	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24381
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100