DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG2712 and ZNF763

DIOPT Version :9

Sequence 1:NP_570028.1 Gene:CG2712 / 31267 FlyBaseID:FBgn0024975 Length:501 Species:Drosophila melanogaster
Sequence 2:NP_001012771.1 Gene:ZNF763 / 284390 HGNCID:27614 Length:397 Species:Homo sapiens


Alignment Length:339 Identity:96/339 - (28%)
Similarity:134/339 - (39%) Gaps:70/339 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   170 EQHEDDLCEIVDDPDPEQRRSRLER--SEPALQCP--ICG------------------------- 205
            |..||..|.......|:.|.:..|:  |..|..|.  :||                         
Human    76 EIKEDSHCGETFTQVPDDRLNFQEKKASPEAKSCDNFVCGEVGIGNSSFNMNIRGDIGHKAYEYQ 140

  Fly   206 -------KQLARKRTFQYHMRLHGQPKIRQEDNDHCIEECLQVEPVLQAKAGEDVYEIVE----- 258
                   |....|:.|:||      |..|.::.:|               .||..|...|     
Human   141 DYAPKPYKCQQPKKAFRYH------PSFRTQERNH---------------TGEKPYACKECGKTF 184

  Fly   259 KSAQTSATQKTLPSGSRPWKPLNPSLQCKICGKQLSTNNSFKYHMQLHGTATPYVCTICGESFKT 323
            .|......:..:.||..|:|       ||.|||.:.....:..|.:.|....||.|..|.:||..
Human   185 ISHSGIRRRMVMHSGDGPYK-------CKFCGKAVHCLRLYLIHERTHTGEKPYECKQCVKSFSY 242

  Fly   324 RNARDGHVTLHDRNNPNRCPTCFKVYRQASSLRTHLLIHSGIKPFECSICGKRLTQKSGYKKHML 388
            ......|...|....|..|..|.|.:..:||.:.|...|:|.||:||..|||..:....::.|..
Human   243 SATHRIHERTHTGEKPYECQQCGKAFHSSSSFQAHKRTHTGGKPYECKQCGKSFSWCHSFQIHER 307

  Fly   389 THTGEKPHGCDICGRRFRYSSNLIAHKRCHSQEKPHPCPVCQKRSFGSTSELNRHMLVHSSERPF 453
            |||||||..|..|.:.||...:.:.|||.|:.|||:.|..|:| :|...|.|.||...||:::|:
Human   308 THTGEKPCECSKCNKAFRSYRSYLRHKRSHTGEKPYQCKECRK-AFTYPSSLRRHERTHSAKKPY 371

  Fly   454 GCEQCGKSFKRRIS 467
            .|:||||:...:.|
Human   372 ECKQCGKALSYKFS 385

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG2712NP_570028.1 zf-AD 13..92 CDD:214871
C2H2 Zn finger 286..306 CDD:275368 6/19 (32%)
C2H2 Zn finger 314..334 CDD:275368 5/19 (26%)
C2H2 Zn finger 342..362 CDD:275368 6/19 (32%)
zf-H2C2_2 354..379 CDD:290200 11/24 (46%)
C2H2 Zn finger 370..390 CDD:275368 5/19 (26%)
COG5048 378..>463 CDD:227381 35/84 (42%)
zf-H2C2_2 384..407 CDD:290200 11/22 (50%)
C2H2 Zn finger 398..418 CDD:275368 7/19 (37%)
C2H2 Zn finger 426..447 CDD:275368 8/20 (40%)
zf-H2C2_2 439..464 CDD:290200 11/24 (46%)
C2H2 Zn finger 455..475 CDD:275368 6/13 (46%)
ZNF763NP_001012771.1 KRAB 7..>49 CDD:214630
KRAB 7..46 CDD:279668
C2H2 Zn finger 149..169 CDD:275368 6/25 (24%)
COG5048 202..>390 CDD:227381 69/192 (36%)
C2H2 Zn finger 205..225 CDD:275368 6/19 (32%)
zf-H2C2_2 221..242 CDD:290200 8/20 (40%)
C2H2 Zn finger 233..253 CDD:275368 5/19 (26%)
zf-H2C2_2 247..270 CDD:290200 6/22 (27%)
C2H2 Zn finger 261..281 CDD:275368 6/19 (32%)
zf-H2C2_2 273..297 CDD:290200 11/23 (48%)
C2H2 Zn finger 289..309 CDD:275368 5/19 (26%)
zf-H2C2_2 301..326 CDD:290200 11/24 (46%)
C2H2 Zn finger 317..337 CDD:275368 7/19 (37%)
zf-H2C2_2 332..354 CDD:290200 11/22 (50%)
DUF45 <342..383 CDD:302795 17/41 (41%)
C2H2 Zn finger 345..365 CDD:275368 8/20 (40%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165146610
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.930

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