DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2712 and Zfp709

DIOPT Version :9

Sequence 1:	NP_570028.1	Gene:	CG2712 / 31267	FlyBaseID:	FBgn0024975	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	XP_006252902.1	Gene:	Zfp709 / 266773	RGDID:	628698	Length:	765	Species:	Rattus norvegicus

Alignment Length:	346	Identity:	108/346 - (31%)
Similarity:	154/346 - (44%)	Gaps:	60/346 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   187 QRRSRLERSEPALQCPICGKQLARKRTFQYHMRLHGQPK----------------IRQEDNDHCI 235
            |...|....|....|.:|.|......:.:||.|:|...|                :|..:..|..
  Rat   418 QTHKRCHTGEKPYVCKLCEKAFTTLSSLRYHERIHSGEKPHVCLQCGKGFNSSSTLRIHERTHTG 482

  Fly   236 E---ECLQVEPVL----------QAKAGEDVYEIVEKSAQTSATQKT-------LPSGSRPWKP- 279
            |   :|.|...|.          :..:||..|  |.|....:.|:.|       :..|.:|:|.
  Rat   483 EKPYKCKQCGKVFSVDSSLRCHERIHSGEKPY--VCKQCGKAFTRHTSLRCHERIHCGEKPYKCK 545

  Fly   280 ------LNPS--------------LQCKICGKQLSTNNSFKYHMQLHGTATPYVCTICGESFKTR 324
                  ::.|              ..||:|||..:.::|.:.|.::|....||||..||:.|.:.
  Rat   546 QCGKGFISSSNFRKHEWTHSGEKHCVCKLCGKAFTGHSSLRRHERIHSGEKPYVCKHCGKGFSSL 610

  Fly   325 NARDGHVTLHDRNNPNRCPTCFKVYRQASSLRTHLLIHSGIKPFECSICGKRLTQKSGYKKHMLT 389
            :....|..:|....|:.|.:|.|.:...|:||.|..||||.||..|..|||.....|.::.|...
  Rat   611 SGCQRHEQIHTGEKPHVCKSCGKAFTNPSALRNHERIHSGEKPCICEQCGKGFISFSKFRIHERI 675

  Fly   390 HTGEKPHGCDICGRRFRYSSNLIAHKRCHSQEKPHPCPVCQKRSFGSTSELNRHMLVHSSERPFG 454
            ||||||:.|..||:.|...|:|..|:|.||.|||..|..|.| ||.:.|:..||..:|:.|:||.
  Rat   676 HTGEKPYKCKQCGKAFTGHSSLRRHERIHSGEKPFVCKQCGK-SFYTLSDCQRHEQIHTGEKPFI 739

  Fly   455 CEQCGKSFKRRISLAIHRQSH 475
            |:||||:|.|..||.||.::|
  Rat   740 CKQCGKAFTRSSSLKIHEKTH 760

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2712	NP_570028.1	zf-AD	13..92	CDD:214871
		C2H2 Zn finger	286..306	CDD:275368	7/19 (37%)
		C2H2 Zn finger	314..334	CDD:275368	5/19 (26%)
		C2H2 Zn finger	342..362	CDD:275368	7/19 (37%)
		zf-H2C2_2	354..379	CDD:290200	13/24 (54%)
		C2H2 Zn finger	370..390	CDD:275368	6/19 (32%)
		COG5048	378..>463	CDD:227381	38/84 (45%)
		zf-H2C2_2	384..407	CDD:290200	11/22 (50%)
		C2H2 Zn finger	398..418	CDD:275368	8/19 (42%)
		C2H2 Zn finger	426..447	CDD:275368	8/20 (40%)
		zf-H2C2_2	439..464	CDD:290200	12/24 (50%)
		C2H2 Zn finger	455..475	CDD:275368	11/19 (58%)
Zfp709	XP_006252902.1	KRAB	40..>80	CDD:214630
		KRAB	40..79	CDD:279668
		COG5048	<196..356	CDD:227381
		C2H2 Zn finger	240..256	CDD:275368
		C2H2 Zn finger	264..284	CDD:275368
		zf-H2C2_2	276..301	CDD:290200
		COG5048	288..730	CDD:227381	92/314 (29%)
		C2H2 Zn finger	292..312	CDD:275368
		zf-H2C2_2	304..328	CDD:290200
		C2H2 Zn finger	320..340	CDD:275368
		zf-H2C2_2	332..357	CDD:290200
		C2H2 Zn finger	348..368	CDD:275368
		zf-H2C2_2	360..385	CDD:290200
		C2H2 Zn finger	376..396	CDD:275368
		zf-H2C2_2	388..413	CDD:290200
		C2H2 Zn finger	404..424	CDD:275368	2/5 (40%)
		C2H2 Zn finger	432..452	CDD:275368	6/19 (32%)
		C2H2 Zn finger	460..480	CDD:275368	1/19 (5%)
		zf-H2C2_2	473..496	CDD:290200	6/22 (27%)
		C2H2 Zn finger	488..508	CDD:275368	3/19 (16%)
		zf-H2C2_2	500..525	CDD:290200	5/26 (19%)
		C2H2 Zn finger	516..536	CDD:275368	3/19 (16%)
		zf-H2C2_2	528..551	CDD:290200	3/22 (14%)
		C2H2 Zn finger	544..564	CDD:275368	1/19 (5%)
		C2H2 Zn finger	572..592	CDD:275368	7/19 (37%)
		zf-H2C2_2	584..609	CDD:290200	10/24 (42%)
		C2H2 Zn finger	600..620	CDD:275368	5/19 (26%)
		zf-H2C2_2	614..637	CDD:290200	6/22 (27%)
		C2H2 Zn finger	628..648	CDD:275368	7/19 (37%)
		C2H2 Zn finger	656..676	CDD:275368	6/19 (32%)
		zf-H2C2_2	669..692	CDD:290200	10/22 (45%)
		C2H2 Zn finger	684..704	CDD:275368	8/19 (42%)
		zf-H2C2_2	696..721	CDD:290200	13/25 (52%)
		C2H2 Zn finger	712..732	CDD:275368	8/20 (40%)
		zf-H2C2_2	724..749	CDD:290200	12/24 (50%)
		C2H2 Zn finger	740..760	CDD:275368	11/19 (58%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24381
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100