DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG2712 and AI987944

DIOPT Version :9

Sequence 1:NP_570028.1 Gene:CG2712 / 31267 FlyBaseID:FBgn0024975 Length:501 Species:Drosophila melanogaster
Sequence 2:NP_898990.1 Gene:AI987944 / 233168 MGIID:2142079 Length:406 Species:Mus musculus


Alignment Length:297 Identity:89/297 - (29%)
Similarity:142/297 - (47%) Gaps:23/297 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly   187 QRRSRLERSEPALQCPICGKQLARKRTFQYHMRLHGQPKIRQEDNDHCIEECLQVEPVLQAKAGE 251
            ||..|:..|:...:|..|||..|.:...:.|.|:|.:.|  .::.:.|.:..||:..  :..:.:
Mouse   118 QRHERIHTSKKPYECNQCGKAFAHRSYLRKHKRIHIEEK--PDEWNQCGQGNLQIHK--RTHSAQ 178

  Fly   252 DVYEIVE--------KSAQTSATQKTLPSGSRPWKPLNPSLQCKICGKQLSTNNSFKYHMQLHGT 308
            ..||..:        .|.|......|   |.:|:|       |..|.|..:.....:.|.:.|..
Mouse   179 KPYECNQCGKAFRRHNSLQVHNRTHT---GEKPYK-------CDQCDKAFTQQGHLRIHNRTHTG 233

  Fly   309 ATPYVCTICGESFKTRNARDGHVTLHDRNNPNRCPTCFKVYRQASSLRTHLLIHSGIKPFECSIC 373
            ..||.|..||::|...:....|...|....|..|..|.|.:|:.::|:.|...|:|.||::|..|
Mouse   234 EKPYECNQCGKAFAVHSTLQIHKRTHTAETPYECNQCGKAFRRHNTLQIHKRTHTGEKPYKCDQC 298

  Fly   374 GKRLTQKSGYKKHMLTHTGEKPHGCDICGRRFRYSSNLIAHKRCHSQEKPHPCPVCQKRSFGSTS 438
            .|..:|:...:.|..|||||||:.|..||:.|...|:|:.|:|.|:.|||:.|..|.| :|....
Mouse   299 DKAFSQQGHLRIHKRTHTGEKPYKCSQCGKAFARHSHLLIHERIHTGEKPYRCNQCNK-AFSQYG 362

  Fly   439 ELNRHMLVHSSERPFGCEQCGKSFKRRISLAIHRQSH 475
            .|..|...|::|:|:.|.:|||:|.:...|..|:::|
Mouse   363 GLQIHKSTHTAEKPYECNECGKTFSQHSYLRTHKRTH 399

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG2712NP_570028.1 zf-AD 13..92 CDD:214871
C2H2 Zn finger 286..306 CDD:275368 4/19 (21%)
C2H2 Zn finger 314..334 CDD:275368 5/19 (26%)
C2H2 Zn finger 342..362 CDD:275368 6/19 (32%)
zf-H2C2_2 354..379 CDD:290200 9/24 (38%)
C2H2 Zn finger 370..390 CDD:275368 5/19 (26%)
COG5048 378..>463 CDD:227381 34/84 (40%)
zf-H2C2_2 384..407 CDD:290200 12/22 (55%)
C2H2 Zn finger 398..418 CDD:275368 8/19 (42%)
C2H2 Zn finger 426..447 CDD:275368 6/20 (30%)
zf-H2C2_2 439..464 CDD:290200 10/24 (42%)
C2H2 Zn finger 455..475 CDD:275368 7/19 (37%)
AI987944NP_898990.1 KRAB 4..>45 CDD:214630
KRAB 4..43 CDD:279668
COG5048 51..405 CDD:227381 89/297 (30%)
C2H2 Zn finger 77..96 CDD:275368
C2H2 Zn finger 108..124 CDD:275368 3/5 (60%)
zf-H2C2_2 116..141 CDD:290200 8/22 (36%)
C2H2 Zn finger 132..152 CDD:275368 7/19 (37%)
zf-H2C2_2 167..192 CDD:290200 4/26 (15%)
C2H2 Zn finger 183..203 CDD:275368 2/19 (11%)
zf-H2C2_2 195..220 CDD:290200 9/34 (26%)
C2H2 Zn finger 211..231 CDD:275368 4/19 (21%)
zf-H2C2_2 223..247 CDD:290200 7/23 (30%)
C2H2 Zn finger 239..259 CDD:275368 5/19 (26%)
C2H2 Zn finger 267..287 CDD:275368 6/19 (32%)
zf-H2C2_2 280..304 CDD:290200 9/23 (39%)
C2H2 Zn finger 295..315 CDD:275368 5/19 (26%)
zf-H2C2_2 307..332 CDD:290200 12/24 (50%)
C2H2 Zn finger 323..343 CDD:275368 8/19 (42%)
zf-H2C2_2 335..360 CDD:290200 11/25 (44%)
C2H2 Zn finger 351..371 CDD:275368 6/20 (30%)
C2H2 Zn finger 379..399 CDD:275368 7/19 (37%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24381
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

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