DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2712 and AU041133

DIOPT Version :9

Sequence 1:	NP_570028.1	Gene:	CG2712 / 31267	FlyBaseID:	FBgn0024975	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_001156536.1	Gene:	AU041133 / 216177	MGIID:	2143755	Length:	498	Species:	Mus musculus

Alignment Length:	297	Identity:	96/297 - (32%)
Similarity:	140/297 - (47%)	Gaps:	18/297 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   187 QRRSRLERSEPALQCPICGKQLARKRTFQYHMRLHGQPKIRQEDNDHCIEECLQVEPVLQAK--- 248
            ::..:....|...:|..|||....:.:.|.|.|.|...|  ..|.:.|.:.......:|..|
Mouse   122 RKHEKKHTKEKLYECNHCGKSFPSRNSLQIHNRTHTGEK--PYDCNECGKAFTCSSNLLLHKRTH 184

  Fly   249 AGEDVYEIVE-----KSAQTSATQKTLPSGSRPWKPLNPSLQCKICGKQLSTNNSFKYHMQLHGT 308
            .||..|:..:     .|:......|...:|.:|:       .|..|||..:.:|:.:.|.:.|..
Mouse   185 TGEKPYDCSDCGKAFASSSNLQIHKRKHTGEKPY-------GCNQCGKAFAYSNALQKHERSHTR 242

  Fly   309 ATPYVCTICGESFKTRNARDGHVTLHDRNNPNRCPTCFKVYRQASSLRTHLLIHSGIKPFECSIC 373
            ...|.|..||::|....:...|...|....|..|..|.|.:..:|:|..|...|:|.|||:|:.|
Mouse   243 EKIYECNQCGKAFARHRSLQNHEEHHTLEKPYECSQCGKAFAYSSNLYIHERSHTGEKPFKCTQC 307

  Fly   374 GKRLTQKSGYKKHMLTHTGEKPHGCDICGRRFRYSSNLIAHKRCHSQEKPHPCPVCQKRSFGSTS 438
            ||.....|..:.|..|||||||:.|:.||:.|...|||:.|||.|:.|||:.|..|.| :|..:|
Mouse   308 GKAFPSHSSLQIHERTHTGEKPYDCNECGKAFACRSNLLLHKRTHTGEKPYHCIECGK-AFACSS 371

  Fly   439 ELNRHMLVHSSERPFGCEQCGKSFKRRISLAIHRQSH 475
            .|.:|...|:.|:|:.|.||||:|.||..|.||.:.|
Mouse   372 SLQKHEKTHTGEKPYECNQCGKAFARRSDLYIHERIH 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2712	NP_570028.1	zf-AD	13..92	CDD:214871
		C2H2 Zn finger	286..306	CDD:275368	6/19 (32%)
		C2H2 Zn finger	314..334	CDD:275368	5/19 (26%)
		C2H2 Zn finger	342..362	CDD:275368	6/19 (32%)
		zf-H2C2_2	354..379	CDD:290200	11/24 (46%)
		C2H2 Zn finger	370..390	CDD:275368	6/19 (32%)
		COG5048	378..>463	CDD:227381	38/84 (45%)
		zf-H2C2_2	384..407	CDD:290200	12/22 (55%)
		C2H2 Zn finger	398..418	CDD:275368	10/19 (53%)
		C2H2 Zn finger	426..447	CDD:275368	7/20 (35%)
		zf-H2C2_2	439..464	CDD:290200	11/24 (46%)
		C2H2 Zn finger	455..475	CDD:275368	11/19 (58%)
AU041133	NP_001156536.1	KRAB	4..>47	CDD:214630
		KRAB	4..43	CDD:279668
		COG5048	104..489	CDD:227381	96/297 (32%)
		C2H2 Zn finger	108..128	CDD:275368	0/5 (0%)
		C2H2 Zn finger	136..156	CDD:275368	7/19 (37%)
		zf-H2C2_2	148..173	CDD:290200	7/26 (27%)
		C2H2 Zn finger	164..184	CDD:275368	3/19 (16%)
		zf-H2C2_2	176..201	CDD:290200	5/24 (21%)
		C2H2 Zn finger	192..212	CDD:275368	2/19 (11%)
		zf-H2C2_2	204..229	CDD:290200	7/31 (23%)
		C2H2 Zn finger	220..240	CDD:275368	6/19 (32%)
		zf-H2C2_2	232..257	CDD:290200	7/24 (29%)
		C2H2 Zn finger	248..268	CDD:275368	5/19 (26%)
		C2H2 Zn finger	276..296	CDD:275368	6/19 (32%)
		zf-H2C2_2	288..311	CDD:290200	11/22 (50%)
		C2H2 Zn finger	304..324	CDD:275368	6/19 (32%)
		zf-H2C2_2	316..341	CDD:290200	12/24 (50%)
		C2H2 Zn finger	332..352	CDD:275368	10/19 (53%)
		zf-H2C2_2	344..369	CDD:290200	13/25 (52%)
		C2H2 Zn finger	360..380	CDD:275368	7/20 (35%)
		zf-H2C2_2	372..397	CDD:290200	11/24 (46%)
		C2H2 Zn finger	388..408	CDD:275368	11/19 (58%)
		zf-H2C2_2	400..425	CDD:290200	4/9 (44%)
		C2H2 Zn finger	416..436	CDD:275368
		zf-H2C2_2	428..453	CDD:290200
		C2H2 Zn finger	444..464	CDD:275368
		zf-H2C2_2	456..481	CDD:290200
		C2H2 Zn finger	472..492	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24381
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100