DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG2712 and ZNF555

DIOPT Version :9

Sequence 1:NP_570028.1 Gene:CG2712 / 31267 FlyBaseID:FBgn0024975 Length:501 Species:Drosophila melanogaster
Sequence 2:XP_011526018.1 Gene:ZNF555 / 148254 HGNCID:28382 Length:630 Species:Homo sapiens


Alignment Length:323 Identity:101/323 - (31%)
Similarity:152/323 - (47%) Gaps:46/323 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly   191 RLERSEPALQCPICGKQLARKRTFQYHMRLHGQPKIRQEDNDHCIEECLQVEPVLQAKAGEDVYE 255
            |....|....|.:|||...|..:...|:|:|...|         ..||.|.     .||      
Human   194 RTHNGERPYVCKLCGKTFPRTSSLNRHVRIHTAEK---------TYECKQC-----GKA------ 238

  Fly   256 IVEKSAQTSATQKTLPSGSRPWKPLNPSLQCKICGKQLSTNNSFKYHMQLHGTATPYVCTICGES 320
            .::.|:.||..:.  .:|.:|:|       ||.|||..|.:::|:.|...|....||.|..|.|:
Human   239 FIDFSSLTSHLRS--HTGEKPYK-------CKECGKAFSYSSTFRRHTITHTGEKPYKCKECAEA 294

  Fly   321 FKTRNARDGHVTLHDRNNPNRCPTCFKVYRQASSLRTHLLIHSGIKPFECSICGKRLTQKSGYKK 385
            |...:....|:..|....|::|..|.:.:..:|:.|.|::.|:|.||:||..|||.......:::
Human   295 FSYSSTFRRHMISHTGEKPHKCKECGEAFSYSSAFRRHMITHTGEKPYECKQCGKTFIYLQSFRR 359

  Fly   386 HMLTHTGEKPHGCDICGRRFRYSSNLIAHKRCHSQEKPHPCPVCQKRSFGSTSELNRHMLVHSSE 450
            |...||||||:.|..||:.|.|..:...|:|.|..|||:.|..|.| :|...|....||.||:.|
Human   360 HERIHTGEKPYECKQCGKTFIYPQSFRRHERTHGGEKPYECNQCGK-AFSHPSSFRGHMRVHTGE 423

  Fly   451 RPFGCEQCGKSFKRRISLAIHRQSHKAG-----RQRRRA--------EHEVGVQLEEQDENVE 500
            :|:.|:||||:|...|||..|.::|...     :|..:|        ||   |::..:|::.|
Human   424 KPYECKQCGKTFNWPISLRKHMRTHTREKPYECKQCGKAFSLSACFREH---VRMHPEDKSYE 483

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG2712NP_570028.1 zf-AD 13..92 CDD:214871
C2H2 Zn finger 286..306 CDD:275368 8/19 (42%)
C2H2 Zn finger 314..334 CDD:275368 5/19 (26%)
C2H2 Zn finger 342..362 CDD:275368 5/19 (26%)
zf-H2C2_2 354..379 CDD:290200 11/24 (46%)
C2H2 Zn finger 370..390 CDD:275368 5/19 (26%)
COG5048 378..>463 CDD:227381 34/84 (40%)
zf-H2C2_2 384..407 CDD:290200 11/22 (50%)
C2H2 Zn finger 398..418 CDD:275368 7/19 (37%)
C2H2 Zn finger 426..447 CDD:275368 7/20 (35%)
zf-H2C2_2 439..464 CDD:290200 12/24 (50%)
C2H2 Zn finger 455..475 CDD:275368 10/19 (53%)
ZNF555XP_011526018.1 KRAB 6..>50 CDD:214630
KRAB 6..45 CDD:279668
C2H2 Zn finger 151..168 CDD:275368
C2H2 Zn finger 176..196 CDD:275368 1/1 (100%)
zf-H2C2_2 188..211 CDD:290200 6/16 (38%)
COG5048 200..597 CDD:227381 99/317 (31%)
C2H2 Zn finger 204..224 CDD:275368 7/19 (37%)
zf-H2C2_2 216..239 CDD:290200 9/42 (21%)
C2H2 Zn finger 232..252 CDD:275368 7/32 (22%)
zf-H2C2_2 244..269 CDD:290200 10/33 (30%)
C2H2 Zn finger 260..280 CDD:275368 8/19 (42%)
zf-H2C2_2 273..297 CDD:290200 9/23 (39%)
C2H2 Zn finger 288..308 CDD:275368 5/19 (26%)
zf-H2C2_2 301..325 CDD:290200 5/23 (22%)
C2H2 Zn finger 316..336 CDD:275368 5/19 (26%)
zf-H2C2_2 328..353 CDD:290200 11/24 (46%)
C2H2 Zn finger 344..364 CDD:275368 5/19 (26%)
zf-H2C2_2 356..381 CDD:290200 11/24 (46%)
C2H2 Zn finger 372..392 CDD:275368 7/19 (37%)
zf-H2C2_2 384..409 CDD:290200 10/25 (40%)
C2H2 Zn finger 400..420 CDD:275368 7/20 (35%)
zf-H2C2_2 412..436 CDD:290200 11/23 (48%)
C2H2 Zn finger 428..448 CDD:275368 10/19 (53%)
zf-H2C2_2 440..464 CDD:290200 6/23 (26%)
C2H2 Zn finger 456..476 CDD:275368 5/22 (23%)
C2H2 Zn finger 484..504 CDD:275368 101/323 (31%)
zf-H2C2_2 496..520 CDD:290200
C2H2 Zn finger 512..532 CDD:275368
zf-H2C2_2 525..548 CDD:290200
C2H2 Zn finger 540..560 CDD:275368
zf-H2C2_2 556..577 CDD:290200
C2H2 Zn finger 568..588 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165146658
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24381
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
22.030

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