DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ttm50 and TIM50

DIOPT Version :9

Sequence 1:	NP_001303557.1	Gene:	ttm50 / 31266	FlyBaseID:	FBgn0250874	Length:	428	Species:	Drosophila melanogaster
Sequence 2:	NP_175986.2	Gene:	TIM50 / 842040	AraportID:	AT1G55900	Length:	376	Species:	Arabidopsis thaliana

Alignment Length:	389	Identity:	114/389 - (29%)
Similarity:	183/389 - (47%)	Gaps:	76/389 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 LRLFTCTALPAAAPALFSILHTARGYSSTTKQEAGATGPNDAPEVAPNAPLLAKLFPQTSPEVDS 121
            ||.|:..|....:.:.:|      |.:||....:....||..|             |...|:|::
plant    22 LRCFSAEASSTNSTSRYS------GVTSTQSMFSDFPPPNQPP-------------PPPPPQVEA 67

  Fly   122 NAEQERKKREEEEEKENERAWKRMK-LGFAI---FGGSAVAAGFWAVYEFGKPEVDPNGQPIEDE 182
            .|.....|         ||  |.:| ||:|:   ..|:..|.|: |.:.:...||:...:...:.
plant    68 AAAAATGK---------ER--KGLKYLGYALLWALTGATAATGY-ASFAYTIDEVNEKTKAFRES 120

  Fly   183 FTHKPLVQ--------QYLQRMW--------KSIHYYQRM----------IQEPSRAKLLPDPLK 221
            .|..|:::        :|..:::        ::|..|..:          ..||...|||||  .
plant   121 ATKTPVIKSSGIDVIDKYQTKLYSAAMTGSARAIDKYLELREIVEEQVKGFTEPLSEKLLPD--L 183

  Fly   222 PPYVQPRYTLVLEMKDVLVHPDWTYQTGWRFKKRPGVDHFLAECAKDFEIVVFTAEQGMTVFPIL 286
            .|..|..:||||::.:.|::.||..:.|||..||||||.||....|.:||||::.:..|.|.|:.
plant   184 HPAEQHVFTLVLDLNETLLYTDWKRERGWRTFKRPGVDAFLEHLGKFYEIVVYSDQMEMYVLPVC 248

  Fly   287 DALDPNGYIMYRLVRDATHFVDGHHVKNLDNLNRDLKKVIVVDWDANATKMHPDNTFGLARWHGN 351
            :.|||||||.|:|.|.||.:.:|.|.::|..||||.||::.|..:|..:.:.|:|:..:..:...
plant   249 EKLDPNGYIRYKLARGATKYENGKHYRDLSKLNRDPKKILFVSANAFESTLQPENSVPIKPYKLE 313

  Fly   352 DDDGQLLDLIAFLKIIAQNNVDDVREVLHYYRQFDDPINQFRENQRKLAEQMLEAERIEQSKTK 415
            .||..|:|||.||:.:|:|:..|:|.||..:.:.|            :|::.:: ..||..|.|
plant   314 ADDTALVDLIPFLEYVARNSPADIRPVLASFERKD------------IAKEFID-RSIEYQKRK 364

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ttm50	NP_001303557.1	CPDc	227..355	CDD:214729	52/127 (41%)
TIM50	NP_175986.2	NIF	191..338	CDD:281081	62/146 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	132	1.000	Domainoid score	I1664
eggNOG	1	0.900	-	-		E1_COG5190
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	141	1.000	Inparanoid score	I1782
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1142452at2759
OrthoFinder	1	1.000	-	-		FOG0003614
OrthoInspector	1	1.000	-	-		otm3534
orthoMCL	1	0.900	-	-		OOG6_102279
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2489
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.730