DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ttm50 and ublcp1

DIOPT Version :9

Sequence 1:	NP_001303557.1	Gene:	ttm50 / 31266	FlyBaseID:	FBgn0250874	Length:	428	Species:	Drosophila melanogaster
Sequence 2:	XP_021324596.1	Gene:	ublcp1 / 792145	ZFINID:	ZDB-GENE-040718-3	Length:	371	Species:	Danio rerio

Alignment Length:	253	Identity:	66/253 - (26%)
Similarity:	102/253 - (40%)	Gaps:	55/253 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   170 PEVDP--NGQPIEDEFTHKPLVQQYLQRMWKSIHYYQRMIQEPSRAKLLPDPLKPPYVQPRYTLV 232
            ||.|.  |...||:|.|.....::.|.::.:.:..|:  ::|          |.||....| .||
Zfish   143 PENDDVVNDFDIEEEVTEVENREENLAKIARRVKDYK--VEE----------LNPPRPGKR-LLV 194

  Fly   233 LEMKDVLVHPDWTYQTGWRFKKRPGVDHFLAECAKDFEIVVFTA------EQGMTVFPILDALDP 291
            |::...|.......:||... .||.:..||....:||:||:::|      :..|....:.|  :|
Zfish   195 LDIDYTLFDHKSCAETGHEL-MRPFLHEFLTSAYEDFDIVIWSATSMKWIDAKMKELGVTD--NP 256

  Fly   292 NGYIMYRLVRDATHFVDGH-------HVKNL--------DNLNRDLKKVIVVDWDANATKMHPDN 341
            |..|.:.|  |:...:..|       .||.|        :..||  |..|:.|.......|:|.|
Zfish   257 NYKITFML--DSAAMITVHTPKRGVVEVKPLGVIWGKYSEFYNR--KNTIMFDDIGRNFLMNPQN 317

  Fly   342 TFGL-----ARWHGN-DDDGQLLDLIAFLKIIAQNNVDDVREV--LHYYRQFDDPINQ 391
              ||     .:.|.| :.|.:|..|..:||.||:  :||...:  .|:.|......||
Zfish   318 --GLKIRPFMKAHLNREKDKELYKLSQYLKEIAK--LDDFSGLNHKHWERYLSKKQNQ 371

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ttm50	NP_001303557.1	CPDc	227..355	CDD:214729	39/154 (25%)
ublcp1	XP_021324596.1	UBQ	59..130	CDD:320785
ublcp1	XP_021324596.1	HAD_IIID1	170..364	CDD:131299	54/217 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5190
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900